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TGF beta 2转化生长因子β2(TGFβ2)抗体

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  • ¥1380 - 2200
  • LMAI Bio
  • LM-20412R
  • 进口/国产
  • 2026年02月03日
  • WB=1:500-2000 ELISA=1:500-1000 IHC-F=1:400-800 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复)
  • Rabbit
  • Human, Mouse, Rat,
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    • 详细信息
    • 文献和实验
    • 技术资料
    • 供应商

      上海联迈生物工程有限公司

    • 库存

      大量

    • 目录编号

      LM-20412R

    • 克隆性

      多克隆

    • 抗原来源

      Rabbit

    • 保质期

      1年

    • 抗体英文名

      TGF beta 2

    • 抗体名

      转化生长因子β2(TGFβ2)抗体

    • 宿主

      Rabbit

    • 适应物种

      Human, Mouse, Rat,

    • 免疫原

      KLH conjugated synthetic peptide derived from human TGF beta 2:351-414/414

    • 亚型

      IgG

    • 形态

      Lyophilized or Liquid

    • 应用范围

      WB=1:500-2000 ELISA=1:500-1000 IHC-F=1:400-800 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复)

    • 浓度

      1mg/ml

    • 保存条件

      Store at -20 °C

    • 规格

      100ul  200ul

    TGF beta 2转化生长因子β2(TGFβ2)抗体
    英文名称 TGF beta 2
    中文名称 转化生长因子β2(TGFβ2)抗体
    别    名 TGF B2; BSC 1 cell growth inhibitor; BSC-1 cell growth inhibitor; BSC1 cell growth inhibitor; Cetermin; G TSF; G-TSF; Glioblastoma derived T cell suppressor ; Glioblastoma derived T cell suppressor factor; Glioblastoma-derived T-cell suppressor factor; GTSF; MGC116892; Polyergin; TGF beta2; TGF-beta-2; TGF-beta2; TGFB 2; TGFB2; TGFB2_HUMAN; Transforming growth factor beta 2; Transforming growth factor beta-2.  
    规格价格 100ul/1380元 购买    200ul/2200元 购买    大包装/询价
    说 明 书 100ul  200ul
    研究领域 肿瘤  细胞生物  信号转导  干细胞  生长因子和激素  转录调节因子  
    抗体来源 Rabbit
    克隆类型 Polyclonal
    交叉反应 Human, Mouse, Rat, 
    产品应用 WB=1:500-2000 ELISA=1:500-1000 IHC-F=1:400-800 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) 
    not yet tested in other applications.
    optimal dilutions/concentrations should be determined by the end user.
    分 子 量 50kDa
    细胞定位 分泌型蛋白 
    性    状 Lyophilized or Liquid
    浓    度 1mg/ml
    免 疫 原 KLH conjugated synthetic peptide derived from human TGF beta 2:351-414/414 
    亚    型 IgG
    纯化方法 affinity purified by Protein A
    储 存 液 Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4
    保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
    PubMed PubMed
    产品介绍 background:
    Transforming growth factor beta s (TGF beta s) were originally discovered due to their ability to promote anchorage-independent growth of rat NRK fibroblasts in the presence of TGF Alpha. It is now realized that TGF beta s mediate many cell-cell interactions that occur during embryonic development. Three TGF beta s have been identified in mammals. TGF beta 1, TGF beta 2 and TGF beta 3 are each synthesized as precursor proteins that are very similar in that each is cleaved to yield a 112 amino acid polypeptide that remains associated with the latent portion of the molecules. Biologically active TGF beta requires dimerization of the monomers (usually homodimers) and release of the latent peptide portion. Overall, the mature region of the TGF beta 3 protein has approximately 80% identity to the mature region of both TGF beta 1 and TGF beta 2. However, the NH2 terminals or precursor regions of their molecules share only 27% sequence identity.

    Function:
    TGF-beta 2 has suppressive effects on interleukin-2 dependent T-cell growth.

    Subunit:
    Homodimer; disulfide-linked. Heterodimers with TGFB1 and with TGFB3 have been found in bone. Interacts with the serine proteases, HTRA1 and HTRA3. Interacts with ASPN.

    Subcellular Location:
    Secreted.

    DISEASE:
    Note=A chromosomal aberration involving TGFB2 is found in a family with Peters anomaly. Translocation t(1;7)(q41;p21) with HDAC9.

    Similarity:
    Belongs to the TGF-beta family.

    SWISS:
    P61812

    Gene ID:
    7042

    Database links:
    Entrez Gene: 7042 Human
    Entrez Gene: 21808 Mouse
    Omim: 190220 Human
    SwissProt: P21214 Cow
    SwissProt: P61812 Human
    SwissProt: P27090 Mouse
    Unigene: 133379 Human
    Unigene: 18213 Mouse


    Important Note:
    This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. 

     
    产品图片
    产品细节图片1
    Sample: MDA-MB-231 (human)cell Lysate at 40 ug
    Primary: Anti- TGF beta2 (bs-20412R)at 1/300 dilution
    Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
    Predicted band size: 50 kD
    Observed band size: 48 kD
    产品细节图片2
    Sample:
    Placenta (Mouse)Lysate at 40 ug
    Bladder (Mouse)Lysate at 40 ug
    Primary: Anti-TGF beta 2(bs-20412R)at 1/300 dilution
    Secondary: IRDye800CW Goat Anti-RabbitIgG at 1/20000 dilution
    Predicted band size: 50kD
    Observed band size: 50kD

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    图标文献和实验
    相关实验
    • 转化生长因子β2TGF-β2)酶联免疫分析

      转化生长因子 β 2(TGF- β 2) 酶联免疫 分析 试剂 盒使用说明书 本试剂仅供研究使用          目的:本试剂盒用于测定人血清,血浆及相关液体样本中 转化生长因子β2TGF-β2) 的含量。 实验原理 :    本试剂盒应用双抗体夹心法测定 标本 中 人 转化生长因子 β 2( TGF- β 2) 水平。用纯化的 人 转化生长因子 β 2( TGF- β 2) 抗体包被微孔板,制成固相抗体,往包被单抗的微孔中依次加入

    • 转化生长因子-β(TGF-β)

      一、转化生长因子-β(TGF-β) 转化生长因子-β(transforming growth factor-β,TGF-β)是属于一组新近发现的调节细胞生长和分化的TGF-β超家族。这一家族除TGF-β外,还有活化素(activins)、抑制素(inhibins)、缪勒氏管抑制质(Mullerian inhibitor substance,MIS)和骨形成蛋白(bone morpho-genetic proteins,BMPs

    • 转化生长因子a(TGF- a)酶联免疫分析

      转化生长因子 a (TGF- a ) 酶联免疫 分析 试剂 盒使用说明书 本试剂仅供研究使用 目的:本试剂盒用于测定人血清,血浆,细胞上清及相关液体样本中 转化生长因子 a (TGF- a ) 的含量。 实验原理 : 本试剂盒应用双抗体夹心法测定 标本 中 人 转化生长因子 a (TGF- a ) 水平。用纯化的 人 转化生长因子 a (TGF- a ) 抗体包被微孔板,制成固相抗体,往包被单抗的微孔中依次加入 转化生长因子

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