PRKRIR蛋白激酶PKR抑制蛋白PRKRIR抗体

PRKRIR蛋白激酶PKR抑制蛋白PRKRIR抗体

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  • ¥1380 - 2200
  • LMAI Bio
  • LM-19963R
  • 进口/国产
  • 2025年07月13日
  • WB=1:500-2000 ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复)
  • Rabbit
  • Human, Mouse, Rat, Dog, Pig, Horse, Rabbit,
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    • 详细信息
    • 技术资料
    • 供应商

      上海联迈生物工程有限公司

    • 库存

      大量

    • 目录编号

      LM-19963R

    • 克隆性

      多克隆

    • 抗原来源

      Rabbit

    • 保质期

      1年

    • 抗体英文名

      PRKRIR

    • 抗体名

      蛋白激酶PKR抑制蛋白PRKRIR抗体

    • 宿主

      Rabbit

    • 适应物种

      Human, Mouse, Rat, Dog, Pig, Horse, Rabbit,

    • 免疫原

      KLH conjugated synthetic peptide derived from human PRKRIR:301-400/761

    • 亚型

      IgG

    • 形态

      Lyophilized or Liquid

    • 应用范围

      WB=1:500-2000 ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复)

    • 浓度

      1mg/ml

    • 保存条件

      Store at -20 °C

    • 规格

      100ul  200ul

    PRKRIR蛋白激酶PKR抑制蛋白PRKRIR抗体
    英文名称 PRKRIR
    中文名称 蛋白激酶PKR抑制蛋白PRKRIR抗体
    别    名 52 kDa repressor of the inhibitor of the protein kinase; 58 kDa interferon induced protein kinase interacting protein; DAP4; Death associated protein 4; Inhibitor of protein kinase PKR; Interferon inducible double stranded RNA dependent inhibitor; MGC102750; P52rIPK; P58 repressor; p58IPK interacting protein; THAP domain containing protein 0; THAP0. P52K_HUMAN   
    规格价格 100ul/1380元 购买    200ul/2200元 购买    大包装/询价
    说 明 书 100ul  200ul
    研究领域 细胞生物  激酶和磷酸酶  
    抗体来源 Rabbit
    克隆类型 Polyclonal
    交叉反应 Human, Mouse, Rat, Dog, Pig, Horse, Rabbit, 
    产品应用 WB=1:500-2000 ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) 
    not yet tested in other applications.
    optimal dilutions/concentrations should be determined by the end user.
    分 子 量 88kDa
    细胞定位 细胞核 
    性    状 Lyophilized or Liquid
    浓    度 1mg/ml
    免 疫 原 KLH conjugated synthetic peptide derived from human PRKRIR:301-400/761 
    亚    型 IgG
    纯化方法 affinity purified by Protein A
    储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
    保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
    PubMed PubMed
    产品介绍 background:
    PRKRIR is upstream regulator of interferon induced serine/threonine protein kinase R (PKR). It may block the PKR inhibitory function of P58IPK, resulting in the restoration of kinase activity and suppression of cell growth. 

    Function:
    Upstream regulator of interferon-induced serine/threonine protein kinase R (PKR). May block the PKR-inhibitory function of P58IPK, resulting in restoration of kinase activity and suppression of cell growth.

    Subunit:
    Interacts with P58IPK, probably sequestring it.

    Subcellular Location:
    Nucleus

    Similarity:
    Contains 1 THAP-type zinc finger.

    SWISS:
    O43422

    Gene ID:
    5612

    Database links:

    Entrez Gene: 5612 Human

    Entrez Gene: 72981 Mouse

    Entrez Gene: 308845 Rat

    Omim: 607374 Human

    SwissProt: O43422 Human

    SwissProt: Q9CUX1 Mouse

    SwissProt: Q9R0T3 Rat

    Unigene: 503315 Human



    Important Note:
    This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. 
     
    产品图片 PRKRIR蛋白激酶PKR抑制蛋白PRKRIR抗体
    Sample: 
    Muscle (Mouse) Lysate at 40 ug
    Primary: Anti-PRKRIR (bs-19963R) at 1/300 dilution
    Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
    Predicted band size: 88 kD
    Observed band size: 88 kD

    PRKRIR蛋白激酶PKR抑制蛋白PRKRIR抗体
    Paraformaldehyde-fixed, paraffin embedded (mouse brain tissue); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (PRKRIR) Polyclonal Antibody, Unconjugated (bs-19963R) at 1:400 overnight at 4°C, followed by operating according to SP Kit(Rabbit) (sp-0023) instructionsand DAB staining.
    PRKRIR蛋白激酶PKR抑制蛋白PRKRIR抗体
    Paraformaldehyde-fixed, paraffin embedded (human colon carcinoma); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (PRKRIR) Polyclonal Antibody, Unconjugated (bs-19963R) at 1:400 overnight at 4°C, followed by operating according to SP Kit(Rabbit) (sp-0023) instructionsand DAB staining.

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