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- 核受体筛选模型
- 2026年04月07日
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- 详细信息
- 文献和实验
- 技术资料
- 服务名称：
药物活性筛选服务
- 提供商：
武汉合研生物医药科技有限公司
武汉合研生物医药科技有限公司坐落于光谷生物城，是一家专注于提供新药发现阶段的技术服务，以中小微新药研发企业为服务主体的创新型公司。合研生物拥有一支训练有素的药物研发技术团队，提供的服务覆盖虚拟筛选、酶学靶点筛选、抗肿瘤药物活性评价、细胞功能学检测、药理病理学服务等各项技术。我们的技术团队在分子生物学、细胞生物学、结构生物学等领域具有丰富的经验，通过酶水平、细胞水平测定等技术平台帮助客户进行化合物筛选及化合物特性、作用机制等研究。合研生物以高效、高性价比的专业服务帮助客户更快地达到目标，帮助客户推进药物发现的进程。
我们的优势
合研生物拥有丰富的核受体筛选经验，可提供96孔板型的筛选模式，加速您的药物研发进程。
| Target | Assay | Format |
| ER alpha | Cell based | 96 |
| ER beta | Cell based | 96 |
| glucocorticoid receptor (GR) | Cell based | 96 |
| LXR (liver X receptor) beta | Cell based | 96 |
| Androgen Receptor | Cell based | 96 |
| Constitutive Androstane Receptor (CAR) | Cell based | 96 |
| ERR (estrogen related receptor) alpha | Cell based | 96 |
| ERR (estrogen related receptor) beta | Cell based | 96 |
| Estrogen Related Receptor (ERR) gamma | Cell based | 96 |
| FXR (farnesoid X receptor) | Cell based | 96 |
| LXR (liver X receptor) alpha | Cell based | 96 |
| PPAR alpha | Cell based | 96 |
| PPAR delta | Cell based | 96 |
| PPAR gamma | Cell based | 96 |
| Progesterone Receptor | Cell based | 96 |
| PXR (SXR) | Cell based | 96 |
| RAR (retinoic acid receptor) beta | Cell based | 96 |
| Retinoic Acid Receptor (RAR) alpha | Cell based | 96 |
| Retinoic Acid Receptor (RAR) gamma | Cell based | 96 |
| Retinoid X Receptor (RXR) beta | Cell based | 96 |
| TR (thyroid receptor) alpha | Cell based | 96 |
| TR (thyroid receptor) beta | Cell based | 96 |
| TR-FRET LXR (liver X receptor) beta | Cell based | 96 |
| Vitamin D Receptor (VDR) | Cell based | 96 |
| mineralocorticoid receptor(MR) | Cell based | 96 |
| Retinoid X Receptor (RXR) alpha | Cell based | 96 |
| Retinoid X Receptor (RXR) gamma | Cell based | 96 |
| constitutive androstane receptor isoform 1 | Cell based | 96 |
| constitutive androstane receptor isoform 3 | Cell based | 96 |
| RAR-related orphan receptor gamma (RORγ) | Cell based | 96 |
| Aryl Hydrocarbon Receptor | Cell based | 96 |
| Pregnane X Receptor | Cell based | 96 |
| Nuclear factor (erythroid-derived 2)-like 2 (Nrf2) | Cell based | 96 |
| Liver Receptor Homolog-1 | Cell based | 96 |
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文献和实验【求助】PPARγ基因的序列参与者：清风一号有谁能提供PPARγ基因的序列吗?我将十分感激，谢谢！！！！参与者：yangea楼主的描述不清楚，PPARγ基因的序列，哪个种属？楼主可以按照下述方法自己查找所需要的：1、打开ncbi的主页2、在search项下拉菜单中选择gene，同时在右边for查找项后输入您需要查找的项目，如PPARγ AND Homo sapiens或PPARγ AND Mus musculus（并列上种属，缩小查找范围）3、找所列出信息与所查最为相关的项，点击进入4、会看到
Determination of PPAR Expression by Western Blot
named PPARα, PPARβ (also called PPARδ), and PPARγ have been identified. Up and down-regulations of one or more of these receptors are encountered during development, physiological adaptations, and in several diseases. Therefore, the ability to accurately
PPAR SUMOylation: Some Useful Experimental Tips
detection of the PPAR proteins. For that purpose, cells are transfected with both 6xHistidine-tagged SUMO and PPAR expression vectors. Since the polyHistidine tag binds to nickel cationic ion-linked agarose matrix (Ni-NTA matrix
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