RING finger protein 189 antibody

RING finger protein 189 antibo

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  • ¥1380 - 2200
  • 康朗生物
  • kl-6872R
  • 中国/美国/德国
  • 2025年11月11日
  • WB=1:500-2000 ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 IF=1:100-500
  • Rabbit
  • Human, Mouse, Rat, Dog, Pig, Cow, Rabbit, Sheep,
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    • 详细信息
    • 技术资料
    • 供应商

      上海康朗生物科技有限公司

    • 库存

      大量

    • 目录编号

      kl-6872R

    • 克隆性

      多克隆

    • 抗原来源

      Rabbit

    • 保质期

      12个月

    • 抗体英文名

      RING finger protein 189 antibody

    • 抗体名

      环指蛋白189抗体

    • 宿主

      Rabbit

    • 适应物种

      Human, Mouse, Rat, Dog, Pig, Cow, Rabbit, Sheep,

    • 免疫原

      KLH conjugated synthetic peptide derived from human RING finger protein 189:251-363/363

    • 亚型

      IgG

    • 形态

      冻干粉或液体

    • 应用范围

      WB=1:500-2000 ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 IF=1:100-500

    • 浓度

      1mg/ml

    • 保存条件

      -20 °C

    • 规格

      100ul 200ul

    RING finger protein 189 antibody
    中文名称 环指蛋白189抗体
    别    名 CARP-2; CARP2; Caspase regulator CARP2; Caspases 8 and 10 associated RING finger protein 2; Caspases-8 and -10-associated RING finger protein 2; E3 ubiquitin protein ligase rififylin; E3 ubiquitin-protein ligase rififylin; Fring; FYVE RING finger protein Sakura; FYVE-RING finger protein Sakura; Rffl; RFFL_HUMAN; Rififylin; RING finger and FYVE like domain containing protein; RING finger and FYVE-like domain-containing protein 1; RING finger protein 189; RING finger protein 34 like; RING finger protein 34-like; RNF189; RNF34L.  
    规格价格 100ul/1380元 购买    200ul/2200元 购买    大包装/询价
    说 明 书 100ul  200ul
    研究领域 细胞生物  信号转导  细胞凋亡  转录调节因子  
    抗体来源 Rabbit
    克隆类型 Polyclonal
    交叉反应 Human, Mouse, Rat, Dog, Pig, Cow, Rabbit, Sheep, 
    产品应用 WB=1:500-2000 ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 IF=1:100-500 (石蜡切片需做抗原修复) 
    not yet tested in other applications.
    optimal dilutions/concentrations should be determined by the end user.
    分 子 量 40kDa
    细胞定位 细胞浆 细胞膜 
    性    状 Lyophilized or Liquid
    浓    度 1mg/ml
    免 疫 原 KLH conjugated synthetic peptide derived from human RING finger protein 189:251-363/363 
    亚    型 IgG
    纯化方法 affinity purified by Protein A
    储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
    保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
    PubMed PubMed
    产品介绍 background:
    Has E3 ubiquitin protein ligase activity. Regulates the levels of CASP8 and CASP10 by targeting them for proteasomal degradation. Has anti-apoptotic activity. May bind phosphatidylinositol phosphates.

    Subunit:
    Binds CASP8 and CASP10.

    Subcellular Location:
    Cytoplasm. Membrane; Peripheral membrane protein.

    Tissue Specificity:
    Ubiquitous. Detected in spleen, thymus, prostate, testis, ovary, small intestine, colon and peripheral blood leukocytes.

    Post-translational modifications:
    Rapidly degraded after stimulation with TNFSF10, probably by caspases.
    Auto-ubiquitinated (in vitro).
    Palmitoylated.

    Similarity:
    Contains 1 FYVE-type zinc finger. 
    Contains 1 RING-type zinc finger. 
    Contains 2 SAP domains.

    SWISS:
    Q8WZ73

    Gene ID:
    117584

    Database links:

    Entrez Gene: 530263 Cow

    Entrez Gene: 117584 Human

    Entrez Gene: 67338 Mouse

    Entrez Gene: 282844 Rat

    Omim: 609735 Human

    SwissProt: Q8WZ73 Human

    SwissProt: Q6ZQM0 Mouse

    SwissProt: Q8CIN9 Rat

    Unigene: 13680 Human

    Unigene: 341608 Mouse

    Unigene: 159718 Rat



    Important Note:
    This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. 
     
    产品图片 RING finger protein 189 antibo
    Sample: 
    Liver (Mouse) Lysate at 40 ug
    Primary: Anti-RING finger protein 189 (bs-6872R) at 1/300 dilution
    Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
    Predicted band size: 40 kD
    Observed band size: 40 kD

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