Acidic (leucine rich) nuclear phosphoprotein 32 family, member C; ANP32 C; Phosphoprotein 32 related protein 1; Tumorigenic protein pp32r1.
规格价格
100ul/1380元 购买 200ul/2200元 购买 大包装/询价
说 明 书
100ul 200ul
研究领域
肿瘤 免疫学
抗体来源
Rabbit
克隆类型
Polyclonal
交叉反应
Human, Mouse, Rat, Dog, Cow, Horse, Rabbit,
产品应用
WB=1:500-2000 ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
分 子 量
26kDa
细胞定位
细胞核
性 状
Lyophilized or Liquid
浓 度
1mg/ml
免 疫 原
KLH conjugated synthetic peptide derived from human ANP32C:81-180/234
亚 型
IgG
纯化方法
affinity purified by Protein A
储 存 液
0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件
Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
PubMed
PubMed
产品介绍
background: The protein encoded by ANP32C is one of at least two proteins that are similar in amino acid sequence to PP32 and are part of the same acidic nuclear phosphoprotein gene family. However, unlike PP32, the encoded protein is tumorigenic. The tumor suppressor function of PP32 has been localized to a 25 amino acid region that is divergent between PP32 and the protein encoded by this gene. This gene does not contain introns.
Tissue Specificity: Expressed in activated stem cells, such as mobilized CD34+ cells and cord blood CD34+ cells, but not in resting bone marrow CD34+ cells. Expressed in a variety of neoplastic cell lines, mainly in prostatic adenocarcinoma cell lines. Not expressed in normal prostatic tissue.
Similarity: Belongs to the ANP32 family. Contains 4 LRR (leucine-rich) repeats.
SWISS: O43423
Gene ID: 23520
Database links:
Entrez Gene: 23520 Human
Entrez Gene: 448829 Mouse
Entrez Gene: 680377 Rat
Omim: 606877 Human
SwissProt: O43423 Human
SwissProt: Q64G17 Mouse
Unigene: 661161 Human
Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.