ADAM17 antibody

价格¥780 - 2200

品牌康朗生物
货号kl-4236R
产地中国/美国/德国
更新日期2025年11月10日

应用范围WB=1:500-2000 ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 Flow-Cyt=1μg/Test IF=1:100-500
宿主Rabbit
适应物种Human, Mouse, Rat, Dog, Pig, Cow, Rabbit,

上海康朗生物科技有限公司

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详细信息
技术资料

供应商：
上海康朗生物科技有限公司
库存：
大量
目录编号：
kl-4236R
克隆性：
多克隆
抗原来源：
Rabbit
保质期：
12个月
抗体英文名：
ADAM17 antibody
抗体名：
肿瘤坏死因子α转换酶抗体
宿主：
Rabbit
适应物种：
Human, Mouse, Rat, Dog, Pig, Cow, Rabbit,
免疫原：
KLH conjugated synthetic peptide derived from human ADAM17:201-300/824 <Extracellular>
亚型：
IgG
形态：
冻干粉或液体
应用范围：
WB=1:500-2000 ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 Flow-Cyt=1μg/Test IF=1:100-500
浓度：
1mg/ml
保存条件：
-20 °C
规格：
50ul 100ul 200ul

ADAM17 antibody

中文名称	肿瘤坏死因子α转换酶抗体
别名	A disintegrin and metalloproteinase domain 17; ADAM 17; ADAM metallopeptidase domain 17; ADAM17 protein; CD 156b; CD156b; CD156b antigen; CSVP; MGC71942; Snake venom like protease; TACE; TNF alpha convertase; TNF alpha converting enzyme; Tumor Necrosis Factor Alpha Converting Enzyme; A disintegrin and metalloproteinase domain 17 (tumor necrosis factor, alpha, converting enzyme); ADA17_HUMAN.
	Specific References (1) \| bs-4236R has been referenced in 1 publications. [IF=2.08] Li, Qing, et al. "Identification of ADAM10 and ADAM17 with potential roles in the spermatogenesis of the Chinese mitten crab, Eriocheir sinensis." Gene(2015). WB ; PubMed:25703701
规格价格	50ul/780元购买 100ul/1380元购买 200ul/2200元购买大包装/询价
说明书	50ul 100ul 200ul
研究领域	肿瘤免疫学神经生物学信号转导转录调节因子
抗体来源	Rabbit
克隆类型	Polyclonal
交叉反应	Human, Mouse, Rat, Dog, Pig, Cow, Rabbit,
产品应用	WB=1:500-2000 ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 Flow-Cyt=1μg/Test IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
分子量	68/91kDa
细胞定位	细胞膜
性状	Lyophilized or Liquid
浓度	1mg/ml
免疫原	KLH conjugated synthetic peptide derived from human ADAM17:201-300/824 <Extracellular>
亚型	IgG
纯化方法	affinity purified by Protein A
储存液	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件	Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
PubMed	PubMed
产品介绍	background: This gene encodes a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biologic processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. The protein encoded by this gene functions as a tumor necrosis factor-alpha converting enzyme; binds mitotic arrest deficient 2 protein; and also plays a prominent role in the activation of the Notch signaling pathway. [provided by RefSeq]. Subunit: Interacts with MAD2L1, MAPK14 and MUC1. Subcellular Location: Membrane. Tissue Specificity: Ubiquitously expressed. Expressed at highest levels in adult heart, placenta, skeletal muscle, pancreas, spleen, thymus, prostate, testes, ovary and small intestine, and in fetal brain, lung, liver and kidney. Similarity: Contains 1 disintegrin domain. Contains 1 peptidase M12B domain. SWISS: P78536 Gene ID: 6868 Database links: Entrez Gene: 6868 Human Entrez Gene: 11491 Mouse Entrez Gene: 57027 Rat Omim: 603639 Human SwissProt: P78536 Human SwissProt: Q9Z0F8 Mouse SwissProt: Q9Z1K9 Rat Unigene: 404914 Human Unigene: 27681 Mouse Unigene: 144585 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
产品图片	Sample: HepG2(Human) Cell Lysate at 30 ug Primary: Anti-ADAM17 (bs-4236R) at 1/500 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 68/93 kD Observed band size: 63/120 kD Sample: Testis (Mouse) Lysate at 40 ug Primary: Anti-ADAM17 (bs-4236R) at 1/500 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 68/93 kD Observed band size: 93/120 kD Blank control: Molt4. Primary Antibody (green line): Rabbit Anti-ADAM17 antibody (bs-4236R-PE) Dilution: 3μg /10^6 cells; Isotype Control Antibody (orange line): Rabbit IgG . Dilution: 1μg /test. Protocol The cells wereincubated in 5%BSA to block non-specific protein-protein interactions for 30 min at at room temperature .Cells stained with Primary Antibody for 30 min at room temperature. Acquisition of 20,000 events was performed. Blank control: Molt4. Primary Antibody (green line): Rabbit Anti-ADAM17 antibody (bs-4236R-FITC) Dilution: 3μg /10^6 cells; Isotype Control Antibody (orange line): Rabbit IgG . Dilution: 1μg /test. Protocol The cells wereincubated in 5%BSA to block non-specific protein-protein interactions for 30 min at at room temperature .Cells stained with Primary Antibody for 30 min at room temperature. Acquisition of 20,000 events was performed. Blank control: U937 (fixed with 2% paraformaldehyde (10 min)). Primary Antibody:Rabbit Anti-ADAM17 antibody(bs-4236R), Dilution: 1μg in 100 μL 1X PBS containing 0.5% BSA; Isotype Control Antibody: Rabbit IgG(orange) ,used under the same conditions ); Secondary Antibody: Goat anti-rabbit IgG-PE(white blue), Dilution: 1:200 in 1 X PBS containing 0.5% BSA.