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- 详细信息
- 文献和实验
- 技术资料
- 库存:
217
- 英文名:
Recombinant Rabbit T-lymphocyte Activation Antigen CD86
- 保质期:
长期
- 供应商:
北京百奥莱博科技有限公司
- 保存条件:
冻干蛋白置于-20℃以下可长期保存,室温
特别声明:本产品及我公司所售其他产品均为科研类试剂产品,严禁用于药物、医疗及其他非科研用途。
北京百奥莱博专注于生命科学和生物技术领域,致力于为客户提供包括重组兔B7-2(CD86)厂家在内的一系列分子生物学试剂产品,并提供一系列相关的技术服务。
名称:重组兔B7-2(CD86)厂家
编号:JN1574
规格:10μg|50μg|500μg|1mg
英文名:Recombinant Rabbit T-lymphocyte Activation Antigen CD86
品牌:百奥莱博
产地:北京
本品由我们的哺乳动物细胞表达系统制备而成,目的基因编码的Ala23-Arg246在C端含有His标签。
B7-2/CD86质量控制:>95%(还原性SDS-PAGE)
B7-2/CD86制剂:冻干品
B7-2/CD86保存:
冻干蛋白置于-20℃以下可长期保存,室温条件下可稳定保存3周。
复溶蛋白溶液可在4~7℃保存2~7天,可分装后置于-20℃保存三个月。
B7-2/CD86复溶:
打开试剂管前请先离心。
复溶浓度推荐大于100μg/ml。
冻干蛋白请溶于ddH2O。
复溶后,请根据用量分装冻存,避免反复冻融。
关于B7-2/CD86:
T-lymphocyte activation antigen CD86 (B7-2) is a glycosylated protein in the B7 family. B7 family members are transmembrane cell surface molecules that play important roles in immune activation and the maintenance of immune tolerance. It is highly expressed on activated antigen presenting cells. CD86 involved in the costimulatory signal essential for T-lymphocyte proliferation and interleukin-2 production, by binding CD28 or CTLA-4. It may play a critical role in the early events of T-cell activation and costimulation of naive T-cells, such as deciding between immunity and anergy that is made by T-cells within 24 hours after activation. It is expressed by activated B-lymphocytes and monocytes and promoted by MARCH8 and results in endo*(代"c")ytosis and lysosomal degradation.
重组兔B7-2(CD86)厂家极具性价比,此外,我公司正火爆促销以下产品:
·重组人MECR(线粒体反式烯脂酰-CoA还原酶)
编号:JN0763
英文名称:Recombinant Human Trans-2-Enoyl-CoA Reductase Mitochondrial
规格:10μg|50μg|500μg|1mg
本品由我们的哺乳动物细胞表达系统制备而成,目的基因编码的Pro54-Met373在C端含有His标签。
MECR质量控制:>95%(还原性SDS-PAGE)
MECR制剂:冻干品
MECR保存:
冻干蛋白置于-20℃以下可长期保存,室温条件下可稳定保存3周。
复溶蛋白溶液可在4~7℃保存2~7天,可分装后置于-20℃保存三个月。
MECR复溶:
打开试剂管前请先离心。
复溶浓度推荐大于100μg/ml。
冻干蛋白请溶于ddH2O。
复溶后,请根据用量分装冻存,避免反复冻融。
关于MECR:
Trans-2-Enoyl-CoA Reductase Mitochondrial (MECR) belongs to the zinc-containing alcohol dehydrogenase family. MECR localizes to the mitochondrion. It is highly expressed in skeletal and heart muscle and expressed at lower levels in the placenta, liver, kidney and pancreas, with weakly or no expression in the lung. MECR exists as a homodimer, which catalyzes the reduction of trans-2-enoyl-CoA to acyl-CoA with chain length from C6 to C16 in an NADPH-dependent manner with preference to medium chain length substrate. MECR may take part in the mitochondrial synthesis of fatty acids.
重组兔B7-2(CD86)厂家关键词:重组B7-2,重组兔CD86,重组兔B7-2,重组兔B7-2蛋白,JN1574
·重组人半胱*酸蛋白酶ATG4C(自噬相关蛋白酶ATG4C)
编号:JN1753
英文名称:Recombinant Human Autophagy Related 4 Homolog C
规格:10μg|50μg|500μg|1mg
本品由我们的大肠杆菌表达系统制备而成,目的基因编码的Met1-Leu458在C端含有His标签。
ATG4C质量控制:>95%(还原性SDS-PAGE)
ATG4C制剂:液体
ATG4C保存:收到货后请置于-20℃,可保存6个月,避免反复冻融。
关于ATG4C:
Cysteine Protease ATG4C (ATG4C) belongs to the peptidase C54 family. It is required for autophagy, which cleaves the C-terminal part of either MAP1LC3, GABARAPL2 or GABARAP, allowing the liberation of form I. A subpopulation of form I is subsequently converted to a smaller form which is considered to be the phosphatidylethanolamine (PE)-conjugated form, and has the capacity for the binding to autophagosomes. ATG4C is a cytoplasmic protein and high expressed in skeletal muscle, liver, testis and heart. ATG4C can be inhibited by N-ethylmaleimide.
重组兔B7-2(CD86)厂家关键词:重组B7-2,重组兔CD86,重组兔B7-2,重组兔B7-2蛋白,JN1574
·重组人β-Galactosidase(β半乳糖苷酶)
编号:JN1697
英文名称:Recombinant Human beta-Galactosidase
规格:10μg|50μg|500μg|1mg
本品由我们的哺乳动物细胞表达系统制备而成,目的基因编码的Leu24-Val677在C端含有His标签。
β-Galactosidase质量控制:>95%(还原性SDS-PAGE)
β-Galactosidase制剂:液体
β-Galactosidase保存:收到货后请置于-20℃,可保存6个月,避免反复冻融。
关于β-Galactosidase:
β Galactosidase is a lysosomal β Galactosidase that hydrolyzes the terminal β Galactose from Ganglioside and Keratan sulfate. In lysosome, the mature β Galactosidase protein associates with Cathepsin A and Neuraminidase 1 to form the lysosomal multienzyme complex . An alternative splicing at the RNA level of β Galactosidase results a catalytically inactive β Galactosidase that plays an important role in vascular development. Defects of β-galactosidase (GLB1) are the cause of diseases like GM1-gangliosidosis which is a lysosomal storage disease and Morquio Syndrome B that cause patients to have abnormal elastic fibers. More than 100 mutations have been identified for β Galactosidase, which result in different residual activities of the mutant enzymes and a spectrum of symptoms in the two related diseases.
北京百莱博科技有限公司专业生产供应销*(代"售")生物试剂、化学试剂、抗原抗体、血清血浆、Elisa试剂盒,更多试剂产品需求,欢迎来电咨询选购重组兔B7-2(CD86)厂家。
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文献和实验瘤上清(ATCC号TIB120)、B7-2/CD86的杂交瘤上清(Pharmingen)、DEC-205的抗体(ATCC号HB290) 10. 解剖用品 11. 无菌纱布垫 12. 100mm培养皿(如Falcon) 13. 3ml注射器25G,5/8in(1.58cm)针头 14. 9in(23cm)巴氏吸管(填充棉花并高压灭菌) 15. Nytex滤器(3-40/26;Tetko)
加大了。但是随之而来的问题是,这种载体的储存问题。普通的载体我们可以储存在大肠杆菌中,不断复制,不断繁殖,一次购买以后可以省下很多钱。但是载体上有致死基因就只能每次都向厂家购买了。好,现在你把重组质粒构建成功,转入含有DE3片段的大肠杆菌中,利用IPTG进行诱导,发现无法表达,或者表达后想利用其它载体也进行表达以进行比较。那么你可以将外源片段转移到其它载体上,Flexi®系统拥有以下几个载体: Flexi® 载体名称应用表达启动子抗性融合多肽大肠杆菌哺乳动物细胞体外转录 / 翻译N 末端pF
共刺激作用。八十年代末至九十年代初期共刺激分子B7在肿瘤免疫研究中较为深入和广泛。 共刺激分子B7为44-54kD的糖蛋白,属于免疫球蛋白超家族成员。最初发现于活化的B细胞上,它也表达于树突状细胞、活化的巨噬细胞上。除B细胞来源的肿瘤外,其他肿瘤很少表达B7。共刺激分子的缺乏也是肿瘤的弱免疫原性的重要因素。B7又分为B7-1(又名为CD80)和B7-2(又名为CD86),两者仅有25%氨基酸同源。APC活化时,B7-2表达早于 B7-1。B7有两种受体存在于T细胞表面,CD28低亲和力受体
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