名称:JN0736型重组人PACSIN1(神经元蛋白激酶C酪蛋白激酶底物1)品牌 编号:JN0736 规格:10μg|50μg|500μg|1mg 英文名:Recombinant Human Protein Kinase C and Casein Kinase Substrate in Neurons Protein 1 品牌:百奥莱博 产地:北京 本品由我们的哺乳动物细胞表达系统制备而成,目的基因编码的Met1-Ile444在C端含有His标签。
PACSIN1质量控制:>95%(还原性SDS-PAGE)
PACSIN1制剂:液体
PACSIN1保存:收到货后请置于-20℃,可保存6个月,避免反复冻融。
关于PACSIN1: Protein Kinase C and Casein Kinase Substrate in Neurons Protein 1 (PACSIN1) belongs to the PACSIN family. PACSIN1 contains one FCH domain and one SH3 domain. PACSIN1 is highly expressed in the brain and at lower leves in the heart, pancreas, and liver. PACSIN1 may play a role in vesicle formation and transport. PACSIN1 has been shown to interact with DNM1, PACSIN3, Huntingtin, and PACSIN2. In addition, PACSIN1 is phosphorylated by casein kinase 2 (CK2) and protein kinase C (PKC).
关于IL-2RG/CD132: IL2RG contains one fibronectin type-III domain. IL2RG is an important signaling component of many interleukin receptors, including those of interleukin -2, -4, -7 and -21, and is thus referred to as the common gamma chain. IL2RG interacts with SHB upon interleukin stimulation and HTLV-1 accessory protein p12I. Defects in IL2RG are the cause of X-linked combined immunodeficiency (XCID) and severe combined immunodeficiency X-linked T-cell-negative /B-cell-positive / NK-cell-negative (XSCID).
·重组人HTRA2 编号:JN1317 英文名称:Recombinant Human High Temperature Requirement Protein-2 规格:10μg|50μg|500μg|1mg 本品由我们的哺乳动物细胞表达系统制备而成,目的基因编码的Ala134-Glu458在C端含有His标签。
HTRA2质量控制:>95%(还原性SDS-PAGE)
HTRA2制剂:液体
HTRA2保存:收到货后请置于-20℃,可保存6个月,避免反复冻融。
关于HTRA2: High temperature requirement protein A2(HTRA2) is a single-pass membrane protein .It contains 1 PDZ (DHR) domain and belongs to the peptidase S1C family. HtrA2 can be released from the mitochondria during apoptosis and uses its four most N-terminal amino acids to mimic a caspase and be recruited by IAP caspase inhibitors such as XIAP and CIAP1/2.It promotes or induces cell death either by direct binding to and inhibition of BIRC proteins (also called inhibitor of apoptosis proteins, IAPs), leading to an increase in caspase activity, or by a BIRC inhibition-independent, caspase-independent and serine protease activity-dependent mechanism. The protein cleaves THAP5 and promotes its degradation during apoptosis.