北京JN1709型重组人激肽释放酶(Kallikrein 1

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名称：北京JN1709型重组人激肽释放酶(Kallikrein 10)(KLK10)说明书
编号：JN1709
规格：10μg|50μg|500μg|1mg
英文名：Recombinant Human Kallikrein 10
品牌：百奥莱博
产地：北京
本品由我们的哺乳动物细胞表达系统制备而成，目的基因编码的Ala31-Asn276在C端含有His标签。

Kallikrein 10质量控制：＞95%(还原性SDS-PAGE)

Kallikrein 10制剂：液体

Kallikrein 10保存：收到货后请置于-20℃，可保存6个月，避免反复冻融。

关于Kallikrein 10：
Kallikreins are a subgroup of Serine Proteases having diverse physiological functions. Growing evidence suggests that many Kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen Kallikrein subfamily members located in a cluster on chromosome 19. Its encoded protein is secreted and may play a role in suppression of tumorigenesis in breast and prostate cancers. Alternate splicing of this gene results in multiple transcript variants encoding the same protein.

更多有关北京JN1709型重组人激肽释放酶(Kallikrein 10)(KLK10)说明书的价格及使用说明等，请联*(代"系")我们的业务经理王欣女士咨询，我公司还销*(代"售")以下产品：

·重组小鼠2B4(SLAMF4)(CD244)
编号：JN1633
英文名称：Recombinant Mouse Natural killer cell receptor 2B4
规格：10μg|50μg|500μg|1mg
本品由我们的哺乳动物细胞表达系统制备而成，目的基因编码的Gln20-Asn221在C端含有His标签。

2B4/SLAMF4/CD244质量控制：＞95%(还原性SDS-PAGE)

2B4/SLAMF4/CD244制剂：冻干品

2B4/SLAMF4/CD244保存：
冻干蛋白置于-20℃以下可长期保存，室温条件下可稳定保存3周。
复溶蛋白溶液可在4～7℃保存2～7天，可分装后置于-20℃保存三个月。

2B4/SLAMF4/CD244复溶：
打开试剂管前请先离心。
复溶浓度推荐大于100μg/ml。
冻干蛋白请溶于ddH2O。
复溶后，请根据用量分装冻存，避免反复冻融。

关于2B4/SLAMF4/CD244：
Natural killer cell receptor 2B4 (2B4/CD244)is a 66 kDa type I transmembrane glycoprotein in the SLAM subgroup of the CD2 protein family. SLAM family proteins have an extracellular domain (ECD) with two or four Ig-like domains and at least two cytoplasmic immunoreceptor tyrosine-based switch motifs (ITSMs). 2B4 interacts with CD48, while other SLAM family proteins interact in a homophilic manner. The mouse 2B4 cDNA encodes a 397 amino acid (aa) precursor that includes a 19 aa signal sequence, a 207 aa ECD with one Ig-like V-type and one C2-type Ig-like domain, a 21 aa transmembrane segment, and a 150 aa cytoplasmic domain with four ITSMs. Within the ECD, mouse 2B4 shares 46% and 68% aa sequence identity with human and rat 2B4, respectively. 2B4/CD48 signaling cooperates with other receptor systems to either promote or inhibit NK and CD8+ T cell activation. The inhibitory activities are distinct from those of MHC I restricted inhibitory NK cell receptors. Ligation of 2B4 with antibodies or CD48 constructs can directly trigger inhibitory signaling or disrupt an inhibitory interaction, leading to cellular activation. 2B4 can also induce signaling through CD48.


北京JN1709型重组人激肽释放酶(Kallikrein 10)(KLK10)说明书关键词：重组人Kallikrein 10,重组人KLK10,重组人激肽释放酶,重组人激肽释放酶蛋白,JN1709


·重组人IL-1R-L1
编号：JN0400
英文名称：Recombinant Human Interleukin-1 receptor-like 1
规格：10μg|50μg|500μg|1mg
本品由我们的哺乳动物表达系统制备，目的基因编码的Lys19-Phe328在C端含有His标签。

IL-1RL1质量控制：＞95%(还原性SDS-PAGE)。

IL-1RL1制剂：冻干品

IL-1RL1保存：
冻干蛋白可在-20℃长期保存，室温也可稳定保存3周。
复溶蛋白溶液可在4～7℃保存2～7天。
复溶后建议分装冻存在-20℃，可保存3个月，应避免反复冻融。

IL-1RL1复溶：
1、试剂开盖前请先离心。
2、复溶浓度应大于100μg/ml.
3、冻干蛋白溶于ddH2O中
4、复溶后根据使用量分装保存，避免反复冻融。

关于IL-1RL1：
Interleukin 1 receptor-like 1(IL1RL1) is a member of the interleukin-1 receptor family, Contains 3 Ig-like C2-type domains and 1 TIR domain. It is highly expressed in kidney, lung, placenta, stomach, skeletal muscle, colon and small intestine. IL1RL1 is a receptor for interleukin-33, its stimulation recruits MYD88, IRAK1, IRAK4, and TRAF6, followed by phosphorylation of MAPK3/ERK1 and/or MAPK1/ERK2, MAPK14, and MAPK8. IL1RL1 may possibly be involved in helper T-cell function. Soluble IL1RL1 also acts as a negative regulator of Th2 cytokine production, it directly implicated in the progression of cardiac disease.


北京JN1709型重组人激肽释放酶(Kallikrein 10)(KLK10)说明书关键词：重组人Kallikrein 10,重组人KLK10,重组人激肽释放酶,重组人激肽释放酶蛋白,JN1709

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