重组人ULBP-1优惠

特别声明：本产品及我公司所售其他产品均为科研类试剂产品，严禁用于药物、医疗及其他非科研用途。

重组人ULBP-1优惠的品牌：百奥莱博，是优质的重组蛋白产品，用于科研实验，本产品质量好，且极具价格优势，深为用户称道，了解更多重组人ULBP-1等重组蛋白产品请联*(代"系")我司咨询订购。

名称：重组人ULBP-1优惠
编号：JN1437
规格：10μg|50μg|500μg|1mg
英文名：Recombinant Human UL16 Binding Protein-1/NKG2D ligand 1
品牌：百奥莱博
产地：北京
本品由我们的哺乳动物细胞表达系统制备而成，目的基因编码的Gly26-Pro215在C端含有His标签。

ULBP-1质量控制：＞95%(还原性SDS-PAGE)

ULBP-1制剂：冻干品

ULBP-1保存：
冻干蛋白置于-20℃以下可长期保存，室温条件下可稳定保存3周。
复溶蛋白溶液可在4～7℃保存2～7天，可分装后置于-20℃保存三个月。

ULBP-1复溶：
打开试剂管前请先离心。
复溶浓度推荐大于100μg/ml。
冻干蛋白请溶于ddH2O。
复溶后，请根据用量分装冻存，避免反复冻融。

关于ULBP-1：
ULBP1, also known as RAET1I and NKG2DL1, is a member of the ULBP/RAET1 gene family. ULBP1 plays an important role in immune responses, especially in cancer and infectious diseases, and is well-known to bind to NKG2D together with at least ULBP 2 and 3. These proteins are distantly related to major histocomp*(代"a")tibility class I (MHC I) molecules, possessing the alpha 1 and alpha 2 Ig-like domains, but lacking the alpha 3 domain. Unlike MHC Class I, they have no capacity to bind peptide or interact with beta2-microglobulin. It can activate multiple signaling pathways in primary NK cells, gamma delta T cells, and CD8+ alpha beta T cells, resulting in the production of cytokines and chemokines.ULBP1 is expressed in wide range of tissues including heart, brain, lung, liver, bone marrow and some tumor cells, T-cells, B-cells, As an unconventional member of the MHC class I family, ULBP1 is able to interact with soluble CMV glycoprotein UL16 in CMV infected cells. The interaction with UL16 blocked the interaction with the NKG2D receptor, and thus might escape the immune surveillance. Furthermore, UL16 also causes ULBP1 to be retained in the ER and cis-Golgi apparatus so that it does not reach the cell surface. The ULBP1 regulation may have implications for development of new therapeutic strategies against cancer cells.

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重组人ULBP-1优惠关键词：Recombinant Human UL16 Binding Protein-1,重组ULBP-1,百奥莱博,重组人ULBP-1蛋白,JN1437

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重组人ULBP-1优惠关键词：Recombinant Human UL16 Binding Protein-1,重组ULBP-1,百奥莱博,重组人ULBP-1蛋白,JN1437

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北京百莱博科技有限公司是重组蛋白产品的专业生产供应销*(代"售")商，恭候您的咨询选购重组人ULBP-1优惠。