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IL-12 antibody

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  • ¥1380 - 2200
  • 康朗生物
  • kl-23008R
  • 中国/美国/德国
  • 2026年01月06日
  • WB=1:500-2000 ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 Flow-Cyt=3ug/Test ICC=1:100-500 IF=1:100-500
  • Rabbit
  • Mouse, Rat,
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    • 详细信息
    • 文献和实验
    • 技术资料
    • 供应商

      上海康朗生物科技有限公司

    • 库存

      大量

    • 目录编号

      kl-23008R

    • 克隆性

      多克隆

    • 抗原来源

      Rabbit

    • 保质期

      12个月

    • 抗体英文名

      IL-12 antibody

    • 抗体名

      白介素12抗体

    • 宿主

      Rabbit

    • 适应物种

      Mouse, Rat,

    • 免疫原

      KLH conjugated synthetic peptide derived from mouse IL-12:21-100/215

    • 亚型

      IgG

    • 形态

      冻干粉或液体

    • 应用范围

      WB=1:500-2000 ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 Flow-Cyt=3ug/Test ICC=1:100-500 IF=1:100-500

    • 浓度

      1mg/ml

    • 保存条件

      -20 °C

    • 规格

      100ul 200ul

    IL-12 antibody
    中文名称 白介素12抗体
    别    名 IL12; IL-12; CLMF p35; CLMF1; CTL maturation factor (TcMF); Cytotoxic lymphocyte maturation factor 1; Cytotoxic lymphocyte maturation factor 35 kDa subunit; IL 12 subunit p35; IL12A; Interleukin 12 alpha chain; Interleukin 12 p35; Interleukin 12A; Natural killer cell stimulatory factor 1; CLMF; CLMF p35; Cytotoxic lymphocyte maturation factor 35 kDa subunit; IL-12 subunit p35; IL-12A; IL12 subunit p35; IL12A; IL12A_HUMAN; Interleukin 12 p35; Interleukin 12A; Interleukin-12 subunit alpha; NFSK; NK cell stimulatory factor chain 1; NKSF1. NK cell stimulatory factor chain 1; NKSF1; p35; IL12A_MOUSE.  
    规格价格 100ul/1380元 购买    200ul/2200元 购买    大包装/询价
    说 明 书 100ul  200ul
    研究领域 肿瘤  细胞生物  免疫学  生长因子和激素  
    抗体来源 Rabbit
    克隆类型 Polyclonal
    交叉反应 Mouse, Rat, 
    产品应用 WB=1:500-2000 ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 Flow-Cyt=3ug/Test ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) 
    not yet tested in other applications.
    optimal dilutions/concentrations should be determined by the end user.
    分 子 量 22kDa
    细胞定位 分泌型蛋白 
    性    状 Lyophilized or Liquid
    浓    度 1mg/ml
    免 疫 原 KLH conjugated synthetic peptide derived from mouse IL-12:21-100/215 
    亚    型 IgG
    纯化方法 affinity purified by Protein A
    储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
    保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
    PubMed PubMed
    产品介绍 background:
    IL-12 protein is a cytokine produced primarily by monocytes and to a lesser extent by lymphocytes. This cytokine has pleiotropic effects in immunoregulation and inflammation. It down-regulates the expression of Th1 cytokines, MHC class II Ags, and costimulatory molecules on macrophages. It also enhances B cell survival, proliferation, and antibody production. This cytokine can block NF-kappa B activity, and is involved in the regulation of the JAK-STAT signaling pathway. Knockout studies in mice suggested the function of this cytokine as an essential immunoregulator in the intestinal tract.

    Function:
    Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine-activated Killer cells, and stimulate the production of IFN-gamma by resting PBMC.

    Subunit:
    Heterodimer with IL12B; disulfide-linked. The heterodimer is known as interleukin IL-12.

    Subcellular Location:
    Secreted.

    Similarity:
    Belongs to the IL-6 superfamily.

    SWISS:
    P43431

    Gene ID:
    16159

    Database links:

    Entrez Gene: 16159 Mouse

    Entrez Gene: 84405 Rat

    SwissProt: P43431 Mouse

    SwissProt: Q9R103 Rat

    Unigene: 103783 Mouse

    Unigene: 207199 Rat



    Important Note:
    This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. 
     
    产品图片 产品细节图片1
    Blank control (blue line): Mouse spleen (fixed with 70% ice-cold methanol overnight at 4℃). 
    Primary Antibody (green line): Rabbit Anti- IL-12 antibody (bs-23008R),ilution: 1μg /10^6 cells; 
    Isotype Control Antibody (orange line): Rabbit IgG .
    Secondary Antibody (white blue line): Goat anti-rabbit IgG-FITC,Dilution: 1μg /test. 

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    图标文献和实验
    相关实验
    • Generation of Antibody Molecules Through Antibody Engineering

      been overcome to a large extent using genetic-engineering techniques to produce chimeric mouse/human and completely human antibodies. Such an approach is particularly suitable because of the domain structure of the antibody molecule ( 2 ), where functional

    • 人白介素-12 p40(IL-12 p40)ELISA试剂盒 说明书

        上海西唐生物科技有限公司   021-55229872,  65333639   www.westang.com 人白介素-12 p40 (IL-12 p40)ELISA 试剂盒  ( 用于血清、血浆、细胞培养上清液和其它生物体液内 )   原理 本实验采用双抗体夹心  ABC-ELISA 法。用抗人   IL-12 p40   单抗包被于酶标板上,标准品和样品中的   IL-12 p40与单抗

    • IL-12相关问题

      mapan777:不知道哪位能告诉我IL-12IL-12p40、IL-12p35、IL-12p70之间的关系是什么啊?丁香园网友qdwanfeng2007认为:我也正想研究il-12,希望能和你共同探讨一下,P40和P35是P70的两个亚基吧?丁香园网友mapan777认为:是的,它们联合起来起作用,我想做PCR,但是快被这个引物折磨死了,不知楼上是要做什么?丁香园网友qdwanfeng2007认为:我想研究研究白介素12的抗肿瘤作用和机理,没大研究过PCR,可能帮不了你。是不是引物

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