- ¥780 - 2200
- LMAI Bio
- LM-0508R
- 进口/国产
- 2025年07月13日
- WB=1:500-2000 ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 IF=1:100-500 （石蜡切片需做抗原修复）
- Rabbit
- Human, Mouse, Rat, Chicken, Pig, Rabbit, Anser,
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- 详细信息
- 文献和实验
- 技术资料
- 供应商：
上海联迈生物工程有限公司
- 库存：
大量
- 目录编号：
LM-0508R
- 克隆性：
多克隆
- 抗原来源：
Rabbit
- 保质期：
1年
- 抗体英文名：
PRL
- 抗体名：
泌乳素抗体
- 宿主：
Rabbit
- 适应物种：
Human, Mouse, Rat, Chicken, Pig, Rabbit, Anser,
- 免疫原：
KLH conjugated synthetic peptide derived from human PRL:165-227/227
- 亚型：
IgG
- 形态：
Lyophilized or Liquid
- 应用范围：
WB=1:500-2000 ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 IF=1:100-500 （石蜡切片需做抗原修复）
- 浓度：
1mg/ml
- 保存条件：
Store at -20 °C
- 规格：
50ul 100ul 200ul
| 英文名称 | PRL |
| 中文名称 | 泌乳素抗体 |
| 别 名 | Luteotropic Hormone; Mammotropin; OTTHUMP00000017727; PRL; Prolactin; Prolactin precursor; PRL_HUMAN. |
 |
Specific References (2) | bs-0508R has been referenced in 2 publications.
[IF=0.00] Xu, Qian, et al. "CYCLIN G1 INHIBITS THE PROLIFERATION OF MOUSE ENDOMETRIAL STROMAL CELL IN DECIDUALIZATION." IF(ICC) ; Mouse.
PubMed:0
[IF=3.32] Hu, Bin, et al. "IFN?\?? Inhibits Osteopontin Expression in Human Decidual Stromal Cells and can be Attenuated by 1??, 25?\Dihydroxyvitamin D3."rican Journal of Reproductive Immunology 68.4 (2012): 353-361..rch Human.
PubMed:22784028
|
| 规格价格 | 50ul/780元 购买 100ul/1380元 购买 200ul/2200元 购买 大包装/询价 |
| 说 明 书 | 50ul 100ul 200ul |
| 研究领域 | 细胞生物 信号转导 生长因子和激素 激酶和磷酸酶 内分泌病 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Human, Mouse, Rat, Chicken, Pig, Rabbit, Anser, |
| 产品应用 | WB=1:500-2000 ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 24kDa |
| 细胞定位 | 分泌型蛋白 |
| 性 状 | Lyophilized or Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human PRL:165-227/227 |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| PubMed | PubMed |
| 产品介绍 | background: This gene encodes the anterior pituitary hormone prolactin. This secreted hormone is a growth regulator for many tissues, including cells of the immune system. It may also play a role in cell survival by suppressing apoptosis, and it is essential for lactation. Alternative splicing results in multiple transcript variants that encode the same protein. [provided by RefSeq, Aug 2011]. Function: Prolactin acts primarily on the mammary gland by promoting lactation. Subcellular Location: Secreted. Similarity: Belongs to the somatotropin/prolactin family. SWISS: P01236 Gene ID: 5617 Database links: Entrez Gene: 5617 Human Entrez Gene: 19109 Mouse Entrez Gene: 24683 Rat Omim: 176760 Human SwissProt: P01236 Human SwissProt: P06879 Mouse SwissProt: P01237 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 产品图片 |
Sample:
A549 cell(human) Lysate at 40 ug Primary: Anti-PRL (bs-0508R) at 1/300 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 24kD Observed band size: 30 kD 
Tissue/cell: human placenta tissue; 4% Paraformaldehyde-fixed and paraffin-embedded;
Antigen retrieval: citrate buffer ( 0.01M, pH 6.0 ), Boiling bathing for 15min; Block endogenous peroxidase by 3% Hydrogen peroxide for 30min; Blocking buffer (normal goat serum,C-0005) at 37℃ for 20 min; Incubation: Anti-PRL Polyclonal Antibody, Unconjugated(bs-0508R) 1:200, overnight at 4°C, followed by conjugation to the secondary antibody(SP-0023) and DAB(C-0010) staining 
Tissue/cell: rat brain tissue; 4% Paraformaldehyde-fixed and paraffin-embedded;
Antigen retrieval: citrate buffer ( 0.01M, pH 6.0 ), Boiling bathing for 15min; Block endogenous peroxidase by 3% Hydrogen peroxide for 30min; Blocking buffer (normal goat serum,C-0005) at 37℃ for 20 min; Incubation: Anti-PRL Polyclonal Antibody, Unconjugated(bs-0508R) 1:200, overnight at 4°C, followed by conjugation to the secondary antibody(SP-0023) and DAB(C-0010) staining |
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文献和实验外周血中泌乳素(prolactin, PRL)水平高于880～1 000 mIU/L或30g/L（即30ng/ml） 时称为高泌乳素血症(hyperprolactinemia )。多数合并继发闭经或偶见原发闭经与泌乳及高泌乳素血症者称为闭经泌乳综合征，是临床常见的一类特异的闭经患者。 目录 • PRL的合成、分泌与调节 • 高泌乳素血症病因 • 高泌乳素血症对下丘脑-垂体-卵巢轴
ng/mL (μg/L)，而正常男性的水平一般是1–20 ng/mL (μg/L) 。 正常的PRL 分泌随时间变化，白天血清PRL 水平比晚上高2–3 倍。 PRL 的生物半衰期大约为20–50 分钟。 月经周期的血清PRL 水平不定，通常在周期中的水平会稍高。出现生理刺激时，比如睡眠、锻炼、乳头刺激 、性交、低血糖、怀孕和手术刺激等，正常个体的泌乳素水平会升高。 泌乳素由脑下垂体腺的前细胞分泌，是乳房
女生吃「丰胸神药」后竟分泌乳汁！检验科医生：这是乳腺增生，还会导致闭经不孕！
内容物进入血中 , 干扰测定。脂血中的脂质可通过对抗体的物理覆盖阻止抗原抗体结合， 因此会导致Ｐ水平明显降低。黄疸标本常含有内源性过氧化物酶 , 对以辣根过氧化酶为标记物的 ELISA 法 , 可能产生非特异性显色而影响检测结果。五、性激素免疫检测方法的特殊注意1. 免疫检测方法中自身抗体与性激素靶抗原形成巨大的复合物。如 PRL 与其 IgG 型抗体结合形成的巨泌乳素免疫复合物使 PRL 假性增高。2. 异嗜性抗体干扰。异嗜性抗体具有多反应性和低亲和力的特点，与检测抗体结合会干扰 FSH、PRL
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