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APOH antibody

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  • ¥780 - 2200
  • 康朗生物
  • kl-1570R
  • 中国/美国/德国
  • 2025年07月15日
  • WB=1:500-2000 ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 IF=1:100-500
  • Rabbit
  • Human, Mouse, Rat, Dog, Cow, Horse, Rabbit,
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    • 详细信息
    • 文献和实验
    • 技术资料
    • 供应商

      上海康朗生物科技有限公司

    • 库存

      大量

    • 目录编号

      kl-1570R

    • 克隆性

      多克隆

    • 抗原来源

      Rabbit

    • 保质期

      12个月

    • 抗体英文名

      APOH antibody

    • 抗体名

      载脂蛋白H抗体

    • 宿主

      Rabbit

    • 适应物种

      Human, Mouse, Rat, Dog, Cow, Horse, Rabbit,

    • 免疫原

      KLH conjugated synthetic peptide derived from human ApoH:281-345/345

    • 亚型

      IgG

    • 形态

      冻干粉或液体

    • 应用范围

      WB=1:500-2000 ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 IF=1:100-500

    • 浓度

      1mg/ml

    • 保存条件

      -20 °C

    • 规格

      50ul 100ul 200ul

    APOH antibody
    中文名称 载脂蛋白H抗体
    别    名 Apolipoprotein H; Activated protein C binding protein; APC inhibitor; APOH; B2G1; beta 2 glycoprotein I; beta 2 glycoprotein I precursor; BG; OTTMUSP00000003033; APOH_HUMAN.  
    规格价格 50ul/780元 购买    100ul/1380元 购买    200ul/2200元 购买    大包装/询价
    说 明 书 50ul  100ul  200ul
    研究领域 心血管  免疫学  合成与降解  糖蛋白  脂蛋白  
    抗体来源 Rabbit
    克隆类型 Polyclonal
    交叉反应 Human, Mouse, Rat, Dog, Cow, Horse, Rabbit, 
    产品应用 WB=1:500-2000 ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 IF=1:100-500 (石蜡切片需做抗原修复) 
    not yet tested in other applications.
    optimal dilutions/concentrations should be determined by the end user.
    分 子 量 36kDa
    性    状 Lyophilized or Liquid
    浓    度 1mg/ml
    免 疫 原 KLH conjugated synthetic peptide derived from human ApoH:281-345/345 
    亚    型 IgG
    纯化方法 affinity purified by Protein A
    储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
    保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
    PubMed PubMed
    产品介绍 background:
    Apolipoprotein H is expressed by placental trophoblast cells at high levels. Although the normal physiological role is not known, the protein appears to act as a co-factor for the binding of autoantibodies to phospholipids to trophoblasts, which is a process involved in the pathogenesis of recurrent miscarriage. 

    Function:
    Binds to various kinds of negatively charged substances such as heparin, phospholipids, and dextran sulfate. May prevent activation of the intrinsic blood coagulation cascade by binding to phospholipids on the surface of damaged cells.

    Subcellular Location:
    Secreted.

    Tissue Specificity:
    Expressed by the liver and secreted in plasma.

    Post-translational modifications:
    N- and O-glycosylated. PubMed:6587378 also reports glycosylation on 'Asn-188' for their allele.

    Similarity:
    Contains 4 Sushi (CCP/SCR) domains.

    SWISS:
    P02749

    Gene ID:
    350

    Database links:

    Entrez Gene: 350 Human

    Entrez Gene: 287774 Rat

    Omim: 138700 Human

    SwissProt: P02749 Human

    SwissProt: P26644 Rat

    Unigene: 445358 Human

    Unigene: 1824 Rat



    Important Note:
    This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. 

    载脂蛋白H(apolipoprotein D,apoH)又称为β2糖蛋白Ⅰ(β2-glycoprotein,β2-GI),是最初是在人血浆的高密度脂蛋白中被分离出来的。apoH在结构上与其他类型的载脂蛋白存在很大的差异,被归入脂肪促成素家族。
    产品图片 产品细节图片1
    Sample: 
    HepG2 Cell (Human) Lysate at 30 ug
    Primary: Anti-APOH (bs- 1570R) at 1/300 dilution
    Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
    Predicted band size: 36 kD
    Observed band size: 35/50 kD

    产品细节图片2
    Sample: 
    A549 Cell (Human) Lysate at 30 ug
    Primary: Anti-APOH (bs- 1570R) at 1/300 dilution
    Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
    Predicted band size: 36 kD
    Observed band size: 35/50 kD
     

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    图标文献和实验
    相关实验
    • Generation of Antibody Molecules Through Antibody Engineering

      been overcome to a large extent using genetic-engineering techniques to produce chimeric mouse/human and completely human antibodies. Such an approach is particularly suitable because of the domain structure of the antibody molecule ( 2 ), where functional

    • The Antibody Molecule

      The importance of antibody molecules was first recognized in the 1890s, when it was shown that immunity to tetanus and diphtheria was caused by antibodies against the bacterial exotoxins (1 ). Around the same time, it was shown that antisera

    • Antibody Storage

        General comments: Antibodies, like most proteins, do not like to be freeze-thawed. Avoid repetitive freezing of your solution. The best way to store your antibody is to keep a high protein concentration (>1 mg/ml), add some protease

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