Acylglycerol O acyltransferase; Adiponutrin; ADPN; C22orf20; Calcium independent phospholipase A2 epsilon; DJ796I17.1; iPLA(2)epsilon; IPLA2-epsilon; Patatin like phospholipase domain containing 3; patatin like phospholipase domain containing protein 3; phospholipase A2, calcium independent, epsilon.
规格价格
100ul/1380元 购买 200ul/2200元 购买 大包装/询价
说 明 书
100ul 200ul
研究领域
肿瘤 心血管 细胞生物 信号转导
抗体来源
Rabbit
克隆类型
Polyclonal
交叉反应
Human,
产品应用
WB=1:500-2000 ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
分 子 量
53kDa
细胞定位
细胞膜
性 状
Lyophilized or Liquid
浓 度
1mg/ml
免 疫 原
KLH conjugated synthetic peptide derived from human PNPLA3:101-200/481
亚 型
IgG
纯化方法
affinity purified by Protein A
储 存 液
0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件
Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
PubMed
PubMed
产品介绍
background: The protein encoded by this gene is a triacylglycerol lipase that mediates triacylglycerol hydrolysis in adipocytes. The encoded protein, which appears to be membrane bound, may be involved in the balance of energy usage/storage in adipocytes. [provided by RefSeq, Jul 2008]
Function: Multifunctional enzyme which has both triacylglycerol lipase and acylglycerol O-acyltransferase activities.
Subcellular Location: Membrane; Single pass type II membrane protein.
DISEASE: Disease susceptibility is associated with variations affecting the gene represented in this entry. Disease description:A condition characterized by accumulation of triglycerides in the liver. It is associated with adverse metabolic consequences, including insulin resistance and dyslipidemia. In a subset of individuals, hepatic steatosis promotes an inflammatory response in the liver, referred to as steatohepatitis, which can progress to cirrhosis and liver cancer. NAFLD is the most common form of liver disease in Western countries.
Similarity: Contains 1 patatin domain.
SWISS: Q9NST1
Gene ID: 80339
Database links:
Entrez Gene: 609368 Dog
Entrez Gene: 101131854 Gorilla
Entrez Gene: 101824852 Hamster
Entrez Gene: 80339 Human
Entrez Gene: 100406659 Marmoset (common)
Entrez Gene: 116939 Mouse
Entrez Gene: 100344884 Rabbit
Entrez Gene: 362972 Rat
Omim: 609567 Human
SwissProt: Q9NST1 Human
SwissProt: Q91WW7 Mouse
Unigene: 654800 Human
Unigene: 390817 Mouse
Unigene: 97779 Rat
Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
产品图片
Sample: HepG2(Human) Cell Lysate at 30 ug Primary: Anti-PNPLA3 (bs-12745R) at 1/300 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 53 kD Observed band size: 53/58 kD