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- 保存条件：
Powder: -20°C, 3 years; 4°C, 2 years. In solvent: -80°C, 6 months; -20°C, 1 month.
- 库存：
货期：1-2天
- 供应商：
MedChemExpress LLC
- CAS号：
7080-50-4
- 规格：
10 mM * 1 mL/5 g
| 规格： | 10 mM * 1 mL | 产品价格： | ￥110.0 |
|---|---|---|---|
| 规格： | 5 g | 产品价格： | ￥100.0 |
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Tosylchloramide sodium trihydrate
CAS No. : 7080-50-4
MCE 国际站：Tosylchloramide sodium trihydrate
产品活性：Tosylchloramide sodium trihydrate (Chloramine T sodium trihydrate) 是广泛厨房，实验室和医院的消毒剂。也用作空气清新剂和除臭剂中的杀生物剂。
研究领域：Anti-infection
作用靶点：Bacterial
In Vitro: Gram-positive growth is reduced by 95% to 100% after tosylchloramide treatment, regardless of dose, with or without serum. E coli (gram-negative; with/without serum) is reduced 94% to 100% at antiseptic concentrations of 300 and 400 ppm. At 200 ppm, E coli growth is fully inhibited without serum present and by 50% with serum. At 100 and 200 ppm, cell viability remains greater than 90% under all experimental conditions. A 300-ppm, 3-minute exposure to tosylchloramide results in cell viability of up to 70%, with longer exposures producing lower viabilities. Serum does not affect cell viability in any condition.
In Vivo: A dose-dependently significant DNA damage in the rat tissues and inflammation is histopathologically noted around the terminal airways of the lung in both male and female rats. The 24-h exposure to 50 mg/L of chloramine-T is toxic for crayfish and leads to substantial loss of energy that became apparent during subsequently conducted physical stress. Tosylchloramide may potentiate the toxicity of many xenobiotics via metabolic activation and/or accumulation of reactive metabolites. The activities of CYP2E1, CYP1A1/2 CYP2B1/2, CYP3A4 and CYP4A1/2 enzymes significantly increase after treatment with 2.50, 5 and 10 mg/kg bw/day tosylchloramide, in a dose-dependent manner. This effect is not observed after tosylchloramide treatment at dose of 1.25 mg/kg bw/day.
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Sodium acetate Buffer (200mM, pH 5.5): Prepare a 200 mM solution of sodium acetate by disolving 12.0 gam of sodium acetate trihydrate in 440 ml of dw. Prepare a 200mM solution of acetic acid by dissolving 690ul of glacial acetic acid to 60 ml
常用化学试剂分子量 Molecular Weights of Commonly Used Chemicals
Potassium Chloride 74.55 dATP, disodium salt 535.1 Potassium Phosphate , anhydrous, monobasic 136.1 Bis 154.17 Potassium Phosphate, trihydrate, dibasic
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