2-(E-2-decenoylamino)ethyl 2-(

cyclohexylethyl) sulfide,137089-36-2

价格询价

品牌MedChemExpress(MCE)
产地美国
货号HY-100287
更新日期2025年12月04日

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2-(E-2-decenoylamino)ethyl 2-(cyclohexylethyl) sulfide

CAS No. : 137089-36-2

MCE 国际站：2-(E-2-decenoylamino)ethyl 2-(cyclohexylethyl) sulfide

产品活性：2-(E-2-decenoylamino)ethyl 2-(cyclohexylethyl) sulfide 是一种由压力诱发的溃疡和低毒性抑制剂，可以在压力引起的溃疡大鼠中，维持磷脂酶 A2 (phospholipase A2) 和前列腺素 E2 (prostaglandin E2) 的含量水平。

研究领域：GPCR/G Protein | Metabolic Enzyme/Protease

作用靶点：Prostaglandin Receptor | Phospholipase

In Vivo: 2-(E-2-decenoylamino)ethyl 2-(cyclohexylethyl) sulfide (compd.III-1α, 100 mg/kg, p.o.) maintains the relative content of Fr.I hexose, lipid peroxide and phospholipase A2 (PLA2) in normal level in ulcerated rats induced by water immersed restrained stress via dosing twice a day for 3 day (b.i.d. for 3 d). 2-(E-2-decenoylamino)ethyl 2-(cyclohexylethyl) sulfide (100 mg/kg, p.o.) reduces the hexosamine content equally with the control group 4 h after the stress loading, and then markedly increases 7 h after stress loading. 2-(E-2-decenoylamino)ethyl 2-(cyclohexylethyl) sulfide (25 mg/kg, p.o.) blocks the reduction of prostaglandin E2 (PGE2) and PGI2 in early phase and accelerates the increase of PGE2 and PGI2 in the late phase of the stress. 2-(E-2-decenoylamino)ethyl 2-(cyclohexylethyl) sulfide (25 mg/kg, p.o.) also significantly accelerates the cell proliferation in fundic glands in gastric mucosa of mice.