deleted in azoospermia-like autosomal,germline specific RNA binding protein,spermatogenesis gene on the Y-like autosomal
Gene Summary:
The DAZ (Deleted in AZoospermia) gene family encodes potential RNA binding proteins that are expressed in prenatal and postnatal germ cells of males and females. The protein encoded by this gene is localized to the nucleus and cytoplasm of fetal germ cells and to the cytoplasm of developing oocytes. In the testis, this protein is localized to the nucleus of spermatogonia but relocates to the cytoplasm during meiosis where it persists in spermatids and spermatozoa. Transposition and amplification of this autosomal gene during primate evolution gave rise to the DAZ gene cluster on the Y chromosome. Mutations in this gene have been linked to severe spermatogenic failure and infertility in males. [provided by RefSeq
Gene Description:
deleted in azoospermia-like
Gene Alias:
DAZH,DAZL1,DAZLA,MGC26406,SPGYLA
Gene Name:
DAZL
Note:
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage Instruction:
Store at -20°C. Aliquot to avoid repeated freezing and thawing.
Storage Buffer:
In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide)
Recommend Usage:
ELISA (1:64000) Western blot (0.1-0.3 ug/mL) Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1-3 ug/mL) The optimal working dilution should be determined by the end user.
Quality Control Testing:
Antibody Reactive Against Synthetic Peptide.
Concentration:
0.5 mg/mL
Purification:
Antigen affinity purification
Form:
Liquid
Reactivity:
Human, Mouse
Theoretical MW (kDa):
33.2
Host:
Goat
Sequence:
C-GNGPQKKSVDR
Immunogen:
A synthetic peptide corresponding to human DAZL.
Product Description:
Goat polyclonal antibody raised against synthetic peptide of DAZL.