This gene encodes a protein involved in endoplasmic reticulum (ER)-associated degradation. The encoded protein removes unfolded proteins, accumulated during ER stress, by retrograde transport to the cytosol from the ER. This protein also uses the ubiquitin-proteasome system for additional degradation of unfolded proteins. This gene and the mitochondrial ribosomal protein L49 gene use in their respective 3' UTRs some of the same genomic sequence. Sequence analysis identified two transcript variants that encode different isoforms. [provided by RefSeq
Gene Description:
synovial apoptosis inhibitor 1, synoviolin
Gene Alias:
HRD1,KIAA1810,MGC40372
Gene Name:
SYVN1
Note:
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage Instruction:
Store at 4°C. For long term storage store at -20°C. Aliquot to avoid repeated freezing and thawing.
Storage Buffer:
In PBS (0.09% sodium azide)
Recommend Usage:
Western Blot (1:1000) Immunohistochemistry (1:50-100) The optimal working dilution should be determined by the end user.
Purification:
Protein G purification
Form:
Liquid
Reactivity:
Human, Mouse
Host:
Rabbit
Immunogen:
A synthetic peptide (conjugated with KLH) corresponding to C-terminus of human SYVN1.
Product Description:
Rabbit polyclonal antibody raised against synthetic peptide of SYVN1.