GFR-alpha 2,PI-linked cell-surface accessory protein,RET ligand 2,TGF-beta related neurotrophic factor receptor 2,TRN receptor, GPI-anchored,glial cell line derived neurotrophic factor receptor, beta,glial cell line-derived neurotrophic factor family rece
Gene Summary:
Glial cell line-derived neurotrophic factor (GDNF) and neurturin (NTN) are two structurally related, potent neurotrophic factors that play key roles in the control of neuron survival and differentiation. The protein encoded by this gene is a member of the GDNF receptor family. It is a glycosylphosphatidylinositol(GPI)-linked cell surface receptor for both GDNF and NTN, and mediates activation of the RET tyrosine kinase receptor. This encoded protein acts preferentially as a receptor for NTN compared to its other family member, GDNF family receptor alpha 1. This gene is a candidate gene for RET-associated diseases. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
Gene Description:
GDNF family receptor alpha 2
Gene Alias:
GDNFRB,NRTNR-ALPHA,NTNRA,RETL2,TRNR2
Gene Name:
GFRA2
Note:
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage Instruction:
Store at -20°C. Aliquot to avoid repeated freezing and thawing.
Storage Buffer:
In PBS (0.02% sodium azide)
Recommend Usage:
Western Blot (1:1000-1:2000) The optimal working dilution should be determined by the end user.
Quality Control Testing:
Antibody Reactive Against Synthetic Peptide.
Form:
Liquid
Reactivity:
Human, Mouse, Rat
Host:
Rabbit
Immunogen:
A synthetic peptide corresponding to amino acids 377-391 of human GFRA2.
Product Description:
Rabbit polyclonal antibody raised against synthetic peptide of GFRA2.