手机验证
上海康朗生物科技有限公司
大量
kl-0734R antibody
多克隆
Rabbit
12个月
KGF antibody
纤维母细胞生长因子7抗体
Rabbit
Human, Mouse, Rat, Chicken, Dog, Pig, Sheep,
KLH conjugated synthetic peptide derived from humna KGF:101-194/194
IgG
冻干粉或液体
WB=1:500-2000 ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 IF=1:100-500
1mg/ml
-20 °C
50ul 100ul 200ul
中文名称 | 纤维母细胞生长因子7抗体 |
别 名 | FGF 7; FGF7; FGF-7; Fibroblast Growth Factor 7;HBGF 7; HBGF7; HBGF-7; Keratinocyte growth factor precursor; Heparin binding growth factor 7; Keratinocyte Growth Factor; FGF7_HUMAN; Heparin-binding growth factor 7. |
Specific References (4) | bs-0734R has been referenced in 4 publications. [IF=0.13] Durak, Hatice, et al. "Effect of Mitomycin C on bFGF, TGF-β1, KGF-1 Expressions after Myringotomy: An Animal Study." J Int Adv Otol 11.3 (2015): 188-91. IHC-P ; Rat. PubMed:26915147 [IF=3.23] Cai, Yujiao, et al. "Keratinocyte growth factor improves epithelial structure and function in a mouse model of intestinal ischemia/reperfusion." PloS one7.9 (2012). WB ; Mouse. PubMed:23028616 [IF=1.89] Cai, Yu-Jiao, et al. "Keratinocyte growth factor up-regulates Interleukin-7 expression following intestinal ischemia/reperfusion in vitro and in vivo." Int J Clin Exp Pathol 5.6 (2012): 569-580. WB ; Mouse. PubMed:22949940 [IF=1.07] Tang, Xiujun, et al. "The influences of adipose-derived stem cells (ASCs) on epithelial-mesenchymal cross-talk factors in the early stage of scar formation." Int J Clin Exp Med 10.1 (2017): 266-275. IHC-P ; Rabbit. PubMed:0 |
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规格价格 | 50ul/780元 购买 100ul/1380元 购买 200ul/2200元 购买 大包装/询价 |
说 明 书 | 50ul 100ul 200ul |
研究领域 | 肿瘤 免疫学 信号转导 生长因子和激素 |
抗体来源 | Rabbit |
克隆类型 | Polyclonal |
交叉反应 | Human, Mouse, Rat, Chicken, Dog, Pig, Sheep, |
产品应用 | WB=1:500-2000 ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
分 子 量 | 18kDa |
细胞定位 | 分泌型蛋白 |
性 状 | Lyophilized or Liquid |
浓 度 | 1mg/ml |
免 疫 原 | KLH conjugated synthetic peptide derived from humna KGF:101-194/194 |
亚 型 | IgG |
纯化方法 | affinity purified by Protein A |
储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
PubMed | PubMed |
产品介绍 | background: KGF is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. This protein is a potent epithelial cell specific growth factor, whose mitogenic activity is predominantly exhibited in keratinocytes but not in fibroblasts and endothelial cells. Studies of mouse and rat homologs of this gene implicated roles in morphogenesis of epithelium, reepithelialization of wounds, hair development and early lung organogenesis. Function: Plays an important role in the regulation of embryonic development, cell proliferation and cell differentiation. Required for normal branching morphogenesis. Growth factor active on keratinocytes. Possible major paracrine effector of normal epithelial cell proliferation. Subunit: Interacts with FGFBP1. Interacts with FGFR2. Affinity between fibroblast growth factors (FGFs) and their receptors is increased by heparan sulfate glycosaminoglycans that function as coreceptors. Subcellular Location: Secreted. Tissue Specificity: Epithelial cell. Similarity: Belongs to the heparin-binding growth factors family. SWISS: P21781 Gene ID: 2252 Database links: Entrez Gene: 2252 Human Entrez Gene: 14178 Mouse Entrez Gene: 29348 Rat Omim: 148180 Human SwissProt: P21781 Human SwissProt: P36363 Mouse SwissProt: Q02195 Rat Unigene: 567268 Human Unigene: 330557 Mouse Unigene: 98842 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. KGF/FGF7 (Fibroblast growth factor 7) 又称:HBGF-7 纤维母细胞生长因子7,是FGF家族的主要成员之一。 FGF家族参与细胞生长、组织修复、胚胎生长发育、组织器官的形成、肿瘤的生长和侵润等诸多生理病理功能。 成纤维细胞生长因子7的促增生作用主要来源于角化上皮细胞而不是间质细胞和内皮细胞,因此人们又称之为:角化上皮细胞生长因子(KGF)。 |
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