JN1708型重组人SPINK1(丝氨酸蛋白酶抑制剂Kaza

特别声明：本产品及我公司所售其他产品均为科研类试剂产品，严禁用于药物、医疗及其他非科研用途。

北京百奥莱博主要从事生物试剂的生产和销*(代"售")，产品线涵盖JN1708型重组人SPINK1(丝*酸蛋白酶抑制剂Kazal 1型)现货供应在内的分子生物学试剂产品，还包括PCR及荧光定量PCR、核酸提取试剂盒类、样本核酸保护试剂、核酸提取、克隆与转化、蛋白纯化、蛋白检测、免疫组化、细胞凋亡与抗体等。

名称：JN1708型重组人SPINK1(丝*酸蛋白酶抑制剂Kazal 1型)现货供应
规格：10μg|50μg|500μg|1mg
品牌：百奥莱博
产地：国产|进口
编号：JN1708
本品由我们的哺乳动物细胞表达系统制备而成，目的基因编码的Asp24-Cys79在C端含有His标签。

SPINK1质量控制：＞95%(还原性SDS-PAGE)

SPINK1制剂：液体

SPINK1保存：收到货后请置于-20℃，可保存6个月，避免反复冻融。

关于SPINK1：
Serine Protease Inhibitor Kazal-Type 1 (SPINK1) is a trypsin inhibitor that prevent the trypsin-catalyzed premature activation of zymogens within the pancreas. Defects in SPINK1 are a cause of pancreatitis (PCTT). A disease characterized by the presence of calculi in pancreatic ducts. It causes severe abdominal pain attacks. Defects in SPINK1 are the cause of susceptibility to tropical calcific pancreatitis (TCP). Recombinant SPINK1 protein (rSPINK1) stimulated cell proliferation in benign RWPE as well as cancerous prostate cells. The research result indicated that the potential of SPINK1 as an extracellular therapeutic target in prostate cancer. In contrast, knockdown of SPINK1 in 22RV1 cells inhibited cell proliferation, cell invasion, and tumor growth in xenograft assays.

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JN1708型重组人SPINK1(丝*酸蛋白酶抑制剂Kazal 1型)现货供应关键词：重组人丝*酸蛋白酶抑制剂Kazal 1型,重组SPINK1,重组人SPINK1蛋白,JN1708


·重组人小泛素相关修饰物2(SUMO2)
编号：JN1958
英文名称：Recombinant Human Small Ubiquitin-Related Modifier 2
规格：10μg|50μg|500μg|1mg
本品由我们的大肠杆菌表达系统制备而成，目的基因编码的Met1-Gly93在N端含有His标签。

SUMO2质量控制：＞95%(还原性SDS-PAGE)

SUMO2制剂：冻干品

SUMO2保存：
冻干蛋白置于-20℃以下可长期保存，室温条件下可稳定保存3周。
复溶蛋白溶液可在4～7℃保存2～7天，可分装后置于-20℃保存三个月。

SUMO2复溶：
打开试剂管前请先离心。
复溶浓度推荐大于100 μg/ml。
冻干蛋白请溶于ddH2O。
复溶后，请根据用量分装冻存，避免反复冻融。

关于SUMO2：
Small Ubiquitin-Related Modifier 2 (SUMO2) is an Ubiquitin-like protein that belongs to the ubiquitin family with SUMO subfamily. It is a family of small, related proteins that can be enzymatically attached to a target protein by a post-translational modification process termed sumoylation. SUMO2 can be covalently attached to proteins as a monomer or as a lysine-linked polymer. Covalent attachment via an isopeptidebond to its substrates requires prior activation by the E1 complex SAE1-SAE2 and linkage to the E2 enzyme UBE2I, and can be promoted by an E3 ligase such as PIAS1-4, RANBP2 or CBX4. This post-translational modification on lysine residues of proteins plays a crucial role in a number of cellular processes such as nuclear transport, DNA replication and repair, mitosis and signal transduction. Polymeric SUMO2 chains are also susceptible to polyubiquitination which functions as a signal for proteasomal degradation of modified proteins.


JN1708型重组人SPINK1(丝*酸蛋白酶抑制剂Kazal 1型)现货供应关键词：重组人丝*酸蛋白酶抑制剂Kazal 1型,重组SPINK1,重组人SPINK1蛋白,JN1708


·*苄青霉素溶液(50mg/ml)
编号：JN0117
规格：1ml×10

·重组小鼠Nogo Receptor
编号：JN1470
英文名称：Recombinant Mouse Nogo-66 Receptor/Reticulon 4 Receptor
规格：10μg|50μg|500μg|1mg
本品由我们的哺乳动物细胞表达系统制备而成，目的基因编码的Cys27-Ser447在C端带有Fc标签。

Nogo Receptor质量控制：＞95%(还原性SDS-PAGE)

Nogo Receptor制剂：冻干品

Nogo Receptor保存：
冻干蛋白置于-20℃以下可长期保存，室温条件下可稳定保存3周。
复溶蛋白溶液可在4～7℃保存2～7天，可分装后置于-20℃保存三个月。

Nogo Receptor复溶：
打开试剂管前请先离心。
复溶浓度推荐大于100 μg/ml。
冻干蛋白请溶于ddH2O。
复溶后，请根据用量分装冻存，避免反复冻融。

关于Nogo Receptor：
Nogo Receptor (NgR) is a glycosylphosphoinositol (GPI)-anchored protein that belongs to the Nogo recptor family. Human NgR is predominantly expressed in neurons and their axons in the central nervous systems. As a receptor for myelin-derived proteins Nogo, myelin-associated glycoprotein (MAG) and myelin oligodendrocyte glycoprotein (OMG), NgR mediates axonal growth inhibition and may play a role in regulating axonal regeneration and plasticity in the adult central nervous system. NgR may be proposed as a potential drug target for treatment of various neurological conditions. Additionally, NgR may play a role in regulating the function of gap junctions.

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