ICAM1/CD54 antibody

价格¥780 - 2200

品牌康朗生物
货号kl-0608R
产地中国/美国/德国
更新日期2025年07月14日

应用范围WB=1:500-2000 ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 Flow-Cyt=1μg/Test ICC=1:100-500 IF=1:100-500
宿主Rabbit
适应物种Human, Mouse, Rat,

上海康朗生物科技有限公司

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详细信息
技术资料

供应商：
上海康朗生物科技有限公司
库存：
大量
目录编号：
kl-0608R
克隆性：
多克隆
抗原来源：
Rabbit
保质期：
12个月
抗体英文名：
ICAM1/CD54 antibody
抗体名：
细胞间粘附分子-1抗体
宿主：
Rabbit
适应物种：
Human, Mouse, Rat,
免疫原：
KLH conjugated synthetic peptide derived from human CD54:201-300/537 <Extracellular>
亚型：
IgG
形态：
冻干粉或液体
应用范围：
WB=1:500-2000 ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 Flow-Cyt=1μg/Test ICC=1:100-500 IF=1:100-500
浓度：
1mg/ml
保存条件：
-20 °C
规格：
50ul 100ul 200ul

ICAM1/CD54 antibody

中文名称	细胞间粘附分子-1抗体
别名	BB2; CD54 antigen; CD54; ICAM1; ICAM 1; ICAM-1; Cell surface glycoprotein P3.58; Human rhinovirus receptor; Intercellular adhesion molecule 1; Major group rhinovirus receptor; MALA2; MyD10; P3.58; Surface antigen of activated B cells; ICAM1_HUMAN; MALA-2; MyD10; intercellular adhesion molecule 1 precursor; intercellular adhesion molecule 1 (CD54), human rhinovirus receptor; major group rhinovirus receptor.
	Specific References (11) \| bs-0608R has been referenced in 11 publications. [IF=2.02] Chu, Changbin, et al. "Celastrol protects kidney against ischemia–reperfusion-induced injury in rats." Journal of Surgical Research (2013). IHC-P ; Rat. PubMed:23981709 [IF=2.59] Park, Sumin, et al. "Protective effect of 7-O-succinyl macrolactin A against intestinal inflammation is mediated through PI3-kinase/Akt/mTOR and NF-κB signaling pathways." European Journal of Pharmacology (2014). WB ; Rat. PubMed:24769511 [IF=3.55] Xiong, H., et al. "Glycyrrhizin Ameliorates Imiquimod-Induced Psoriasis-like Skin Lesions in BALB/c Mice and Inhibits TNF-α-Induced ICAM-1 Expression via NF-κB/MAPK in HaCaT Cells." Cellular Physiology and Biochemistry 35.4 (2015): 1335-1346. IHC-P ; Mouse. PubMed:25720416 [IF=3.23] Chenna Narendra S, Chalise JP, Magnusson M, Uppugunduri S (2015) Local but Not Systemic Administration of Uridine Prevents Development of Antigen-Induced Arthritis. PLoS ONE 10(10): e0141863 IHC-P ; Mouse. PubMed:26512984 [IF=1.93] Tang, Li‐Qin, et al. "The renoprotective effects of berberine and its potential impact on the expression of β‐arrestins and ICAM‐1/VCAM‐1 in streptozocin induced‐diabetic nephropathy rats." Journal of Diabetes (2015). other ; PubMed:26531813 [IF=1.28] Ji, Mingli, et al. "Up-regulation of ICAM-1mRNA and IL-1βmRNA in lung tissues of a rat model of COPD." International Journal of Clinical and Experimental Medicine 8.11 (2016): 21956-21963. IHC-P ; Rat. PubMed:26885167 [IF=0.00] Sumarya, Made, et al. "BETEL LEAF EXTRACTS (PIPER BETLE L.) PREVENT ENDOTHELIAL DYSFUNCTION BY REDUCING THE LEVELS OF URIC ACID AND ICAM-1 EXPRESSION OF THE HYPERURICEMIA WISTAR RATS (RATTUS NORVEGICUS) AORTIC ENDOTHELIAL." Indonesia Journal of Biomedical Science IHC-P ; Rat. PubMed:0 [IF=1.27] Ji, Mingli, et al. "Protective effect of Xuebijing injection against acute lung injury induced by left ventricular ischemia/reperfusion in rabbits."Experimental and Therapeutic Medicine 12.1 (2016): 51-58. IHC-P ; Rabbit. PubMed:27347017 [IF=1.66] Zhang, Xiaomei, et al. "Effect of mild hypothermia on breast cancer cells adhesion and migration." Bioscience Trends 6.6 (2012): 313-324. other ; PubMed:23337791 [IF=0.52] Utomo, Pamudji, et al. "Decreasing SDF1-CXCR4 Expression after Adipose-Derived Mesenchymal Stem Cells (ASCS) Treatment Combined with Freeze-Dried Amniotic Membrane Wrapping in Rat Sciatic Nerve Injury." International Journal of ChemTech Research. IF(ICC) ; Rat. PubMed:0 [IF=3.21] Osada-Oka, Mayuko, et al. "Macrophage-derived exosomes induce inflammatory factors in endothelial cells under hypertensive conditions." Hypertension Research (2016). WB ; Rat. PubMed:27881852
规格价格	50ul/780元购买 100ul/1380元购买 200ul/2200元购买大包装/询价
说明书	50ul 100ul 200ul
研究领域	肿瘤细胞生物免疫学信号转导干细胞细胞膜受体细胞粘附分子细胞表面分子糖蛋白细胞类型标志物 t-淋巴细胞 b-淋巴细胞
抗体来源	Rabbit
克隆类型	Polyclonal
交叉反应	Human, Mouse, Rat,
产品应用	WB=1:500-2000 ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 Flow-Cyt=1μg/Test ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
分子量	56kDa
细胞定位	细胞膜
性状	Lyophilized or Liquid
浓度	1mg/ml
免疫原	KLH conjugated synthetic peptide derived from human CD54:201-300/537 <Extracellular>
亚型	IgG
纯化方法	affinity purified by Protein A
储存液	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件	Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
PubMed	PubMed
产品介绍	background: This gene encodes a cell surface glycoprotein which is typically expressed on endothelial cells and cells of the immune system. It binds to integrins of type CD11a / CD18, or CD11b / CD18 and is also exploited by Rhinovirus as a receptor. [provided by RefSeq, Jul 2008]. Function: ICAM proteins are ligands for the leukocyte adhesion protein LFA-1 (integrin alpha-L/beta-2). During leukocyte trans-endothelial migration, ICAM1 engagement promotes the assembly of endothelial apical cups through ARHGEF26/SGEF and RHOG activation. In case of rhinovirus infection acts as a cellular receptor for the virus. Subunit: Homodimer (Probable). Interacts with human herpesvirus 8 MIR2 protein (Probable). Interacts with MUC1 and promotes cell aggregation in epithelial cells. Interacts with ARHGEF26/SGEF. Binds to coxsackievirus A21 capsid proteins and acts as a receptor for this virus. Subcellular Location: Membrane; Single-pass type I membrane protein. Post-translational modifications: Monoubiquitinated, which is promoted by MARCH9 and leads to endocytosis. Similarity: Belongs to the immunoglobulin superfamily. ICAM family. ontains 5 Ig-like C2-type (immunoglobulin-like) domains. SWISS: P13597 Gene ID: 3383 Database links: Entrez Gene: 3383 Human Entrez Gene: 15894 Mouse Entrez Gene: 25464 Rat Omim: 147840 Human Unigene: 643447 Human SwissProt: P05362 Human SwissProt: P13597 Mouse SwissProt: Q00238 Rat Unigene: 435508 Mouse Unigene: 12 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. CD54（ICAM-1）是分子量为60-110KD的膜型糖蛋白，表达于单核和内皮细胞。许多细胞如B或T淋巴细胞、胸腺细胞、纤维母细胞和上皮细胞都可诱导表达CD54，在调节免疫和炎症反应中CD54有重要作用。
产品图片	Sample: Hela(Human) Cell Lysate at 30 ug Hela KO ICAM1 (Human) Cell Lysate at 30 ug Primary: Anti-ICAM1/CD54 (bs-0608R) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 56 kD Observed band size: 56 kD Sample: Lymph node (Mouse) Lysate at 40 ug Primary: Anti-ICAM1 (bs-0608R) at 1/300 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 56 kD Observed band size: 56 kD Sample: A549(Human) Cell Lysate at 30 ug Primary: Anti-ICAM1 (bs-0608R) at 1/300 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 56 kD Observed band size: 56/69 kD Sample: Lung (Mouse) Lysate at 40 ug Primary: Anti-ICAM1 (bs-0608R) at 1/300 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 56 kD Observed band size: 56/69 kD Sample: Raji(Human) Cell Lysate at 30 ug Primary: Anti-CD54 (bs-0608R) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 56 kD Observed band size: 56 kD Sample: Spleen (Mouse) Lysate at 40 ug Primary: Anti-ICAM1 (bs-0608R) at 1/300 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 56 kD Observed band size: 56/69 kD