北京现货重组人迁移率族蛋白B1(HMGB1)销售

特别声明：本产品及我公司所售其他产品均为科研类试剂产品，严禁用于药物、医疗及其他非科研用途。

北京百奥莱博主要从事生物试剂的生产和销*(代"售")，产品线涵盖北京现货重组人迁移率族蛋白B1(HMGB1)销*(代"售")在内的分子生物学试剂产品，还包括PCR及荧光定量PCR、核酸提取试剂盒类、样本核酸保护试剂、核酸提取、克隆与转化、蛋白纯化、蛋白检测、免疫组化、细胞凋亡与抗体等。

名称：北京现货重组人迁移率族蛋白B1(HMGB1)销*(代"售")
英文名：Recombinant Human High Mobility Group Protein B1
规格：10μg|50μg|500μg|1mg
产地：国产|进口
品牌：百奥莱博
编号：JN0533
本品由我们的哺乳动物细胞表达系统制备而成，目的基因编码的Gly2-Glu215在C端含有His标签。

HMGB1质量控制：＞95%(还原性SDS-PAGE)

HMGB1制剂：液体

HMGB1保存：收到货后请置于-20℃，可保存6个月，避免反复冻融。

关于HMGB1：
High mobility group protein B1 is a member of the HMGB family consisting of three members, HMGB1, HMGB2 and HMGB3.ItContains 2 HMG box DNA-binding domains entitled box A and box B and It is a highly negative-charged C terminus. As a nuclear protein, HMGB1 stabilizes nucleosomes and allows bending of DNA that facilitates gene transcription which is essential for individual survival. Meanwhile, it is revealed that HMGB1 can also act as a cytokine extracellularlly and regulates monocyte, T cell, dendritic cell activities in inflammatory responses.


更多有关北京现货重组人迁移率族蛋白B1(HMGB1)销*(代"售")的价格及使用说明等，请联*(代"系")我们的业务经理王欣女士咨询，我公司还销*(代"售")以下产品：

·重组人TNFα(TNFSF2)
编号：JN0438
英文名称：Recombinant Human Tumor Necrosis Factor alpha
规格：10μg|50μg|500μg|1mg
本品由我们的大肠杆菌表达系统制备而成。

TNFa/TNFSF2 (high active)质量控制：＞95%(还原性SDS-PAGE)


TNFa/TNFSF2 (high active)制剂：冻干品

TNFa/TNFSF2 (high active)保存：
冻干蛋白置于-20℃以下可长期保存，室温条件下可稳定保存3周。
复溶蛋白溶液可在4～7℃保存2～7天，可分装后置于-20℃保存三个月。

TNFa/TNFSF2 (high active)复溶：
打开试剂管前请先离心。
复溶浓度推荐大于100 μg/ml。
冻干蛋白请溶于ddH2O。
复溶后，请根据用量分装冻存，避免反复冻融。

关于TNFa/TNFSF2 (high active)：
Tumor Necrosis Factor-α (TNF-α) is secreted by macrophages, monocytes, neutrophils, T-cells, and NK-cells following stimulation by bacterial LPS. Cells expressing CD4 secrete TNF-α while cells that express CD8 secrete little or no TNF-α. Synthesis of TNF-α can be induced by many different stimuli including interferons, IL2, and GM-CSF. The clinical use of the potent anti-tumor activity of TNF-α has been limited by the proinflammatory side effects such as fever, dose-limiting hypotension, hepatotoxicity, intravascular thrombosis, and hemorrhage. Designing clinically applicable TNF-α mutants with low systemic toxicity has been of intense pharmacological interest. Human TNF-α that binds to murine TNF-R55 but not murine TNF-R7, exhibits retained anti-tumor activity and reduced systemic toxicity in mice comp*(代"a")red with murine TNF-α, which binds to both murine TNF receptors. Based on these results, many TNF-α mutants that selectively bind to TNF-R55 have been designed. These mutants displayed cytotoxic activities on tumor cell lines in vitro and have exhibited lower systemic toxicity in vivo. Recombinant Human TNF-α High Active Mutant differs from the wild-type by amino acid subsitution of amino acids 1-7 with Arg8, Lys9, Arg10 and Phe157. This mutant form has been shown to have increased activity with less inflammatory side effects in vivo.



北京现货重组人迁移率族蛋白B1(HMGB1)销*(代"售")关键词：重组迁移率族蛋白B1,重组人HMGB1,JN0533,重组人迁移率族蛋白B1蛋白


·重组人IL-1R-L2
编号：JN0411
英文名称：Recombinant Human Interleukin-1 receptor-like 2
规格：10μg|50μg|500μg|1mg
本品由我们的哺乳动物表达系统制备，目的基因编码的Asp20-Tyr337在N端含有Fc标签。

IL-1RL2质量控制：＞95%(还原性SDS-PAGE)。

IL-1RL2制剂：冻干品

IL-1RL2保存：
冻干蛋白可在-20℃长期保存，室温也可稳定保存3周。
复溶蛋白溶液可在4～7℃保存2～7天。
复溶后建议分装冻存在-20℃，可保存3个月，应避免反复冻融。

IL-1RL2复溶：
1、试剂开盖前请先离心。
2、复溶浓度应大于100 μg/ml.
3、冻干蛋白溶于ddH2O中
4、复溶后根据使用量分装保存，避免反复冻融。

关于IL-1RL2：
Interleukin-1 receptor-like 2 is a protein that in humans is encoded by the IL1RL2 gene, belongs to the interleukin-1 receptor family.IL1RL2 is the receptor for interleukin-36 (IL36A, IL36B and IL36G). After binding to interleukin-36 associates with the coreceptor IL1RAP to form the interleukin-36 receptor complex which mediates interleukin-36-dependent activation of NF-kappa-B, MAPK and other pathways.


北京现货重组人迁移率族蛋白B1(HMGB1)销*(代"售")关键词：重组迁移率族蛋白B1,重组人HMGB1,JN0533,重组人迁移率族蛋白B1蛋白

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我公司生产供应销*(代"售")的重组蛋白产品正全系列现货促销，满分期待您的垂询选购北京现货重组人迁移率族蛋白B1(HMGB1)销*(代"售")。