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- 详细信息
- 文献和实验
- 技术资料
- 库存:
365
- 英文名:
Recombinant Human C-C Motif Chemokine 5
- 保质期:
2~7天
- 供应商:
北京百奥莱博科技有限公司
- 保存条件:
冻干蛋白可在-20℃
特别声明:本产品及我公司所售其他产品均为科研类试剂产品,严禁用于药物、医疗及其他非科研用途。
北京百奥莱博专业生产销*(代"售")北京重组人趋化因子CCL5(RANTES)哪里卖,我公司供应的分子生物学试剂品类齐全,且具有优势价格,欢迎新老客户垂询订购。
名称:北京重组人趋化因子CCL5(RANTES)哪里卖
产地:国产|进口
品牌:百奥莱博
英文名:Recombinant Human C-C Motif Chemokine 5
规格:10μg|50μg|500μg|1mg
本品由我们的大肠杆菌表达系统制备,目的基因编码的Ser24-Ser91表达纯化而来。
CCL5/RANTES质量控制:>95%(还原性SDS-PAGE)。
CCL5/RANTES制剂:冻干品
CCL5/RANTES保存:
冻干蛋白可在-20℃长期保存,室温也可稳定保存3周。
复溶蛋白溶液可在4~7℃保存2~7天。
复溶后建议分装冻存在-20℃,可保存3个月,应避免反复冻融。
CCL5/RANTES复溶:
1、试剂开盖前请先离心。
2、复溶浓度应大于100 μg/ml.
3、冻干蛋白溶于ddH2O中
4、复溶后根据使用量分装保存,避免反复冻融。
关于CCL5/RANTES:
Human Chemokine (C-C Motif) Ligand 5 (CCL5) plays an active role in recruiting leukocytes into inflammatory sites. CCL5 is secreted by many cell types at inflammatory sites and it exerts a wide range of activities through the receptors CCR1, CCR3, CCR4, and CCR5. N-Terminal truncated CCL5/RANTES, Met-RANTES, and amino-oxypentane (AOP)-RANTES exhibit antagonist or partial agonist functions on their receptors. CCL5/RANTES attracts different subtypes of leukocytes into inflamed tissue and intervenes in a wide range of allergic and autoimmune diseases.
欲了解更多北京重组人趋化因子CCL5(RANTES)哪里卖的品牌、产地、价格及说明书等产品信息,请致电北京百奥莱博科技有限公司,我们将竭诚为您服务,另外,以下产品正在火爆促销:
·重组Ecotin
编号:JN1657
英文名称:Recombinant E. coli Ecotin
规格:10μg|50μg|500μg|1mg
本品由我们的大肠杆菌表达系统制备而成,目标蛋白包含序列(Met1-Arg162)在C端带有His标签。
Ecotin质量控制:>95%(SEC-HPLC,还原性SDS-PAGE)
Ecotin制剂:冻干品
Ecotin保存:
冻干蛋白长期保存应置于-20℃以下,常温可稳定保存3周。
复溶蛋白溶液可在4℃保存2~7天。
复溶后的蛋白溶液应尽量避免反复冻融,可根据使用量分装冻存在-20℃以下长达3个月。
Ecotin复溶:
打开试剂管前请先离心。
复溶浓度推荐大于100 μg/ml。
Dissolve the lyophilized protein in 1X PBS.
复溶后,请根据用量分装冻存,避免反复冻融。
关于Ecotin:
Ecotins are dimeric periplasmic proteins from Escherichia coli and related Gram-negative bacteria that have been shown to be potent and general inhibitors of many trypsin-fold serine proteases of widely varying substrate specificity, which belong to MEROPS peptidase family S1. Ecotin protein inhibits chymotrypsin, trypsin, elastases, factor X, kallikrein as well as a variety of other proteases and has been characterized as an extremely potent anticoagulant and reversible tight-binding inhibitor of human factor Xa (FXa). The power of inhibition is not linked to specific protease specificity. Immobilized Ecotin has been used to affinity-purify recombinant trypsinogen, indicating that it may also be used to purify additional serine protease zymogens. Comp*(代"a")red to other serine protease inhibitors such as members of the serpin family, the reactive site of ecotin is Met104 (P1). Phylogenetic analysis suggested that Ecotin has an exogenous target, possibly neutrophil elastase. Ecotin from E. coli, Yersinia pestis, and Pseudomonas aeruginosa, all species that encounter the mammalian immune system, inhibit neutrophil elastase strongly while ecotin from the plant pathogen Pantoea citrea inhibits neutrophil elastase 1000-fold less potently. Ecotins all potently inhibit pancreatic digestive peptidases trypsin and chymotrypsin, while showing more variable inhibition of the blood peptidases Factor Xa, thrombin, and urokinase-type plasminogen activator. Ecotin is synthesized as a 162 amino acid precursor with a 20 amino acid signal peptide necessary to direct it to the periplasmic space. The mature protein (residues 21 - 162) is expressed and purified.
北京重组人趋化因子CCL5(RANTES)哪里卖关键词:重组趋化因子CCL5,JN0293,重组人RANTES,重组人趋化因子CCL5,重组人趋化因子CCL5蛋白
·重组小鼠CD274(PD-L1)(B7-H1)(C端带His标签)
编号:JN1376
英文名称:Recombinant Mouse Programmed Cell Death 1 Ligand 1
规格:10μg|50μg|500μg|1mg
本品由我们的哺乳动物细胞表达系统制备而成,目的基因编码的Phe19-Thr238在C端含有His标签。
CD274/PD-L1/B7-H1质量控制:>95%(还原性SDS-PAGE)
CD274/PD-L1/B7-H1制剂:冻干品
CD274/PD-L1/B7-H1保存:
冻干蛋白置于-20℃以下可长期保存,室温条件下可稳定保存3周。
复溶蛋白溶液可在4~7℃保存2~7天,可分装后置于-20℃保存三个月。
CD274/PD-L1/B7-H1复溶:
打开试剂管前请先离心。
复溶浓度推荐大于100 μg/ml。
冻干蛋白请溶于ddH2O。
复溶后,请根据用量分装冻存,避免反复冻融。
关于CD274/PD-L1/B7-H1:
Mouse Programmed cell death 1 ligand 1(Cd274,PD-L1), is a member of the growing B7 family of immune proteins.It involved in the costimulatory signal essential for T-cell proliferation and IFNG production in a PDCD1-independent manner. Interaction with PDCD1 inhibits T-cell proliferation by blocking cell cycle progression and cytokine production.B7-H1 has been identified as one of two ligands for programmed death1 (PD1), a member of the CD28 family of immunoreceptors. B7-H1 is constitutively expressed in several organs such as heart, skeletal muscle B7-H1 expression is upregulated in a small fraction of activated T and B cells and a much larger fraction of activated monocytes. The costimulatory function of B7-H1 is critical for enhancing maturation and differentiation of T-cells in lymphoid organs.B7-H1 expression is also induced in dendritic cells and keratinocytes after IFN gamma stimulation. Interaction of B7-H1 with PD1 results in inhibition of TCR-mediated proliferation and cytokine production. The B7-H1:PD1 pathway is involved in the negative regulation of some immune responses and may play an important role in the regulation of peripheral tolerance.
北京重组人趋化因子CCL5(RANTES)哪里卖关键词:重组趋化因子CCL5,JN0293,重组人RANTES,重组人趋化因子CCL5,重组人趋化因子CCL5蛋白
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我公司生产供应销*(代"售")的重组蛋白产品正全系列现货促销,满分期待您的垂询选购北京重组人趋化因子CCL5(RANTES)哪里卖。
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文献和实验上海西唐生物科技有限公司 021-55229872, 65333639 www.westang.com 人趋化因子 (RANTES)ELISA 试剂盒 ( 用于血清、血浆、细胞培养上清液和尿液、唾液生物体液内 ) 原理 本实验采用双抗体夹心 ABC-ELISA 法。用抗人 RANTES/CCL5 单抗包被于酶标板上,标准品和样品中的 RANTES与单抗结合,加入生物
细胞表达的RANTES(CCL5)?这六种重要的诱导性趋化因子通过与相应受体的相互作用参与了大部分的炎症反应。 组成性趋化因子绝大部分与其受体一一对应,一种趋化因子专一性结合一种趋化因子受体;反之也然,趋化 因子受体也只结合相应的一种趋化因子。而诱导性趋化因子的受体则呈现共享性或多员性(redundancy),即一种趋化因子受体可结合多种诱导性趋化因子。 趋化因子及其受体的分类和靶细胞 红底标出的趋化因子为促炎症类;黄底者参与内环境稳定;蓝色者功能混杂。组成性表达的趋化因子
Th2 型细胞因子与介导体液免疫的细胞因子 Th2细胞能分泌IL-4和IL-5等细胞因子,与B细胞增殖、分化、成熟有关,能促进抗体生成,增强抗体介导的体液免疫应答。Th2细胞分泌和表达的因子或受体还包括IL-4R、IL-10、IL-13、IL-13RAl、IL-13RA2、IL-1R1、IL-1R2,以及趋化因子及其受体CCR2(MCP-1)、CCR3、CCR4、CCR9、CCL5(RANTES)、CCL7(MCP-3)、CCL-11(eotaxin
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