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- 详细信息
- 技术资料
- 库存:
413
- 英文名:
Recombinant Mouse Programmed Cell Death 1 Ligand 1
- 保质期:
长期
- 供应商:
北京百奥莱博科技有限公司
- 保存条件:
冻干蛋白置于-20℃
特别声明:本产品及我公司所售其他产品均为科研类试剂产品,严禁用于药物、医疗及其他非科研用途。
北京百奥莱博主要从事生物试剂的生产和销*(代"售"),产品线涵盖北京现货重组小鼠CD274(PD-L1)(B7-H1)(C端带Fc标签)特价优惠在内的分子生物学试剂产品,还包括PCR及荧光定量PCR、核酸提取试剂盒类、样本核酸保护试剂、核酸提取、克隆与转化、蛋白纯化、蛋白检测、免疫组化、细胞凋亡与抗体等。
名称:北京现货重组小鼠CD274(PD-L1)(B7-H1)(C端带Fc标签)特价优惠
英文名:Recombinant Mouse Programmed Cell Death 1 Ligand 1
品牌:百奥莱博
规格:10μg|50μg|500μg|1mg
编号:JN1377
产地:国产|进口
本品由我们的哺乳动物细胞表达系统制备而成,目的基因编码的Phe19-Thr238在C端带有Fc标签。
CD274/PD-L1/B7-H1质量控制:>95%(还原性SDS-PAGE)
CD274/PD-L1/B7-H1制剂:冻干品
CD274/PD-L1/B7-H1保存:
冻干蛋白置于-20℃以下可长期保存,室温条件下可稳定保存3周。
复溶蛋白溶液可在4~7℃保存2~7天,可分装后置于-20℃保存三个月。
CD274/PD-L1/B7-H1复溶:
打开试剂管前请先离心。
复溶浓度推荐大于100 μg/ml。
冻干蛋白请溶于ddH2O。
复溶后,请根据用量分装冻存,避免反复冻融。
关于CD274/PD-L1/B7-H1:
Mouse Programmed cell death 1 ligand 1(Cd274,PD-L1), is a member of the growing B7 family of immune proteins.It involved in the costimulatory signal essential for T-cell proliferation and IFNG production in a PDCD1-independent manner. Interaction with PDCD1 inhibits T-cell proliferation by blocking cell cycle progression and cytokine production.B7-H1 has been identified as one of two ligands for programmed death1 (PD1), a member of the CD28 family of immunoreceptors. B7-H1 is constitutively expressed in several organs such as heart, skeletal muscle B7-H1 expression is upregulated in a small fraction of activated T and B cells and a much larger fraction of activated monocytes. The costimulatory function of B7-H1 is critical for enhancing maturation and differentiation of T-cells in lymphoid organs.B7-H1 expression is also induced in dendritic cells and keratinocytes after IFN gamma stimulation. Interaction of B7-H1 with PD1 results in inhibition of TCR-mediated proliferation and cytokine production. The B7-H1:PD1 pathway is involved in the negative regulation of some immune responses and may play an important role in the regulation of peripheral tolerance.
更多有关北京现货重组小鼠CD274(PD-L1)(B7-H1)(C端带Fc标签)特价优惠的价格及使用说明等,请联*(代"系")我们的业务经理王欣女士咨询,我公司还销*(代"售")以下产品:
·重组人B7-H1(PD-L1)
编号:JN1525
英文名称:Recombinant Human Programmed Cell Death 1 Ligand 1
规格:10μg|50μg|500μg|1mg
本品由我们的哺乳动物细胞表达系统制备而成,目的基因编码的Phe19-Thr239在C端带有Fc标签。
B7-H1/PD-L1质量控制:>95%(还原性SDS-PAGE)
B7-H1/PD-L1制剂:冻干品
B7-H1/PD-L1保存:
冻干蛋白置于-20℃以下可长期保存,室温条件下可稳定保存3周。
复溶蛋白溶液可在4~7℃保存2~7天,可分装后置于-20℃保存三个月。
B7-H1/PD-L1复溶:
打开试剂管前请先离心。
复溶浓度推荐大于100 μg/ml。
冻干蛋白请溶于ddH2O。
复溶后,请根据用量分装冻存,避免反复冻融。
关于B7-H1/PD-L1:
CD274, also known as B7-H1 or programmed death ligand 1 (PD-L1), is a 40 kD type I transmembrane protein and a member of the B7 family within the immunoglobulin receptor superfamily. Programmed death-1 ligand-1 (PD-L1, CD274, B7-H1) has been identified as the ligand for the immunoinhibitory receptor programmed death-1(PD1/PDCD1) and has been demonstrated to play a role in the regulation of immune responses and peripheral tolerance. By binding to PD1 on activated T-cells and B-cells, PD-L1 may inhibit ongoing T-cell responses by inducing apoptosis and arresting cell-cycle progression. Accordingly, it leads to growth of immunogenic tumor growth by increasing apoptosis of antigen specific T cells and may contribute to immune evasion by cancers. PD-L1 thus is regarded as promising therapeutic target for human autoimmune disease and malignant cancers.
北京现货重组小鼠CD274(PD-L1)(B7-H1)(C端带Fc标签)特价优惠关键词:C端带Fc标签,重组小鼠PD-L1,重组小鼠CD274,重组小鼠B7-H1,JN1377
·重组人NPDC1
编号:JN1242
英文名称:Recombinant Human Neural proliferation differentiation and control protein 1
规格:10μg|50μg|500μg|1mg
本品由我们的哺乳动物细胞表达系统制备而成,目的基因编码的Gly35-Asp181在C端含有His标签。
NPDC1质量控制:>95%(还原性SDS-PAGE)
NPDC1制剂:冻干品
NPDC1保存:
冻干蛋白置于-20℃以下可长期保存,室温条件下可稳定保存3周。
复溶蛋白溶液可在4~7℃保存2~7天,可分装后置于-20℃保存三个月。
NPDC1复溶:
打开试剂管前请先离心。
复溶浓度推荐大于100 μg/ml。
冻干蛋白请溶于ddH2O。
复溶后,请根据用量分装冻存,避免反复冻融。
关于NPDC1:
Neural proliferation differentiation and control protein 1(NPDC1) is a protein that in humans is encoded by the NPDC1 gene. It is asingle-pass membrane protein and belongs to the NPDC1/cab-1 family. The protein strongly expressed in adult brain and especially in hippocampus, frontal lobe and temporal lobe. The protein suppresses oncogenic transformation in neural and non-neural cells and down-regulates neural cell proliferation and it might be involved in transcriptional regulation.
北京现货重组小鼠CD274(PD-L1)(B7-H1)(C端带Fc标签)特价优惠关键词:C端带Fc标签,重组小鼠PD-L1,重组小鼠CD274,重组小鼠B7-H1,JN1377
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