Recombinant Murine IL-36γ, 152a.a.

Recombinant Murine IL-36γ, 152

a.a.
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  • ¥1777
  • 联迈生物
  • LM5991-10μg
  • 中国/上海
  • 2025年07月13日
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    • 详细信息
    • 技术资料
    • 库存

      大量

    • 英文名

      Recombinant Murine IL-36γ, 152a.a.

    • 保质期

      一年

    • 供应商

      上海联迈生物工程有限公司

    • 保存条件

      -20℃或更低温度保存

    • 规格

      10μg

    Recombinant Murine IL-36γ, 152a.a.
    产品编号 产品名称 产品包装 产品价格
    LM5991-10μg Recombinant Murine IL-36γ, 152a.a. 10μg 1777.00
     
    Species Gene ID Accession Source Length MW Tag
    Mouse 215257 LM3U0P4 E. coli 152aa 17.3kDa
     
    About this Antibody
    Name Recombinant Murine IL-36γ, 152a.a. (Recombinant Murine Interleukin-36 gamma, 152a.a.; rMuIL-36γ, 152a.a.);Recombinant Mouse IL-36γ, 152a.a. ; 重组小鼠白细胞介素36γ,152a.a.
    Synonyms Interleukin-36 gamma; Interleukin 1 family, member 9; Il1f9
    Purity >97% by SDS-PAGE and HPLC analyses.
    Biological Activity Fully biologically active when compared to standard. The ED50 as determined by inducing IL-6 secretion in murine NIH/3T3 cells is less than 10ng/ml, corresponding to a specific activity of >1.0×105IU/mg.
    Physical Appearance Sterile Filtered White lyophilized (freeze-dried) powder.
    Formulation Lyophilized from a 0.2μm filtered solution in 1M MOPS, 10mM NaAC, pH7.6, with 2mM EDTA, 5% Trehalose, 0.02% Tween-20.
    Endotoxin Less than 0.1EU/μg of rMuIL-36γ, 152a.a. as determined by LAL method.
    Reconstitution We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1% BSA to a concentration of 0.1-1.0mg/ml. Stock solutions should be apportioned into working aliquots and stored at ≤-20℃. Further dilutions should be made in appropriate buffered solutions.
    Category Cytokine
    Background Interleukin-36 (IL-36) is a pro-inflammatory cytokine which plays an important role in the pathophysiology of several diseases. IL-36α, IL-36β, and IL-36γ (formerly IL-1F6, IL-1F8, and IL-1F9) are IL-1 family members that signal through the IL-1 receptor family members IL-1Rrp2 (IL-1RL2) and IL-1RAcP. IL-36γ is secreted when transfected into 293-T cells and it could constitute part of an independent signaling system analogous to interleukin-1 alpha (IL-1A), beta (IL-1B) receptor agonist and interleukin-1 receptor type I (IL-1R1). Furthermore, IL-36γ also can function as an agonist of NF-kappa B activation through the orphan IL-1- receptor-related protein 2. Recombinant murine IL-36γ is synthesized as a 17.3kDa, 152 amino acid (a.a.) protein that contains no signal sequence, no prosegment and no potential N-linked glycosylation site. Murine to human, IL-36γ shares 53% a.a. identity. Within the family, IL-36γ shares about 25% ~ 55% a.a. sequence identity with IL-1RA, IL-1β, IL-36RA, IL-36α, IL- 37, IL-36β and IL-1F10.
    Amino Acid Sequence GRETPDFGEV FDLDQQVWIF RNQALVTVPR SHRVTPVSVT ILPCKYPESL EQDKGIAIYL GIQNPDKCLF CKEVNGHPTL LLKEEKILDL YHHPEPMKPF LFYHTRTGGT STFESVAFPG HYIASSKTGN PIFLTSKKGE YYNINFNLDI KS
    包装清单:
    产品编号 产品名称 包装
    LM5991-2μg Recombinant Murine IL-36γ, 152a.a. 2μg
    LM5991-10μg Recombinant Murine IL-36γ, 152a.a. 10μg
    LM5991-100μg Recombinant Murine IL-36γ, 152a.a. 100μg
    LM5991-1mg Recombinant Murine IL-36γ, 152a.a. 1mg
    - 说明书 1
    保存条件:
           -20℃或更低温度保存,至少一年有效。由于蛋白的每次冻融均会引起部分失活,所以首次配制成相应浓度的储存液后(请根据产品简介中Reconstitution一栏的信息配制储存液),须分装后-20℃或更低温度冻存,以避免反复冻融。
    注意事项:
           由于有些塑料管壁对某些蛋白有较强的吸附作用,溶液中的蛋白很容易粘附在管壁上,并且粘附后的蛋白很难与管壁分离。而载体蛋白(Carrier protein,如0.1% BSA等)的主要作用是预先封闭塑料管壁上的蛋白结合位点,使细胞因子或重组蛋白不会粘附于管壁。所以一定要使用产品简介中Reconstitution一栏的信息配制储存液。
           本产品仅限于专业人员的科学研究用,不得用于临床诊断或治疗,不得用于食品或药品,不得存放于普通住宅内。
           为了您的安全和健康,请穿实验服并戴一次性手套操作。


     

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