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应用于生物医学研究领域的哺乳动物细胞被错误鉴定和交叉污染的问题，一直是普遍存在的一个突出问题。据统计，国外实验室有20%左右的细胞株被错误鉴定和交叉污染，NIH和ATCC近两年都对此发出呼吁，要求研究者对细胞进行鉴定。一些权威杂志在作者投稿时就要求提供细胞株的STR基因型鉴定证明。
近年来，大量研究表明STR基因分型方法是进行细胞交叉污染和性质鉴定的最有效和准确的方法之一，STR基因分型应用于细胞鉴定已被ATCC等机构强烈推荐。
我公司推出了细胞STR鉴定服务并与多家研究机构、细胞中心、生产厂商等建立长期合作关系。现行技术科同时分析多个STR基因座，可以准确的判断交叉污染和细胞类型。微量样本即可满足检测需求，并且可以检测到早期污染。
1、细胞送样要求：
特别提醒：目前只针对人源细胞进行STR鉴定，非人源细胞暂不受理。
拟进行的细胞鉴定的客户首先应在ATCC等官方网站查询需要鉴定的细胞有没有被ATCC等数据库收录，不详之处可咨询公司在线客服。同时请将以下信息发给我公司在线客服：单位名称（发票抬头）、课题负责人（老板）姓名、电话及电子邮箱。公司将拟好的委托合同发送至客户，负责人在合同上签字后和细胞悬液一起快递至公司。
2、送检细胞：
将1×10的五次方以上细胞悬液置于1.5毫升EP管，用封口膜密封，管壁标记清楚细胞的名称（如HepG2），数量较多时可用编号，并附送检清单。随委托合同一起快递至我公司即可（细胞状态与STR检测无关，请放心邮寄）。
3、细胞株鉴定收费标准：
高等院校及科研机构1200元/株，其他机构或个人：1440元/株。细胞株数量大于50的机构另行议价。
4、检测时限：
正常情况下，收到样本后一个工作日完成检测，并出具正式检测报告。
5、报告形式：
针对细胞株鉴定，本公司将出具英文版报告，可直接用于外文杂志投稿。可联系公司在线客服索取报告模板及样式。
6、标注优惠政策：
如客户在发表的高水平SCI论文（IF>8）中标注细胞株鉴定由我公司完成，我们承诺为客户免费检测两株细胞株。标注格式如下：The cell lines were characterized by Genetic Testing Biotechnology Corporation (Suzhou, China) using short tandem repeat (STR) markers.
7、利用苏州鉴达生物科技细胞株鉴定服务发表的部分高水平(IF>5)论文（截止2023-12-18）
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文献和实验该产品被引用文献
1. Xiangwei Zeng et al., The SMARCA4R1157W mutation facilitates chromatin remodeling and confers PRMT1/SMARCA4 inhibitors sensitivity in colorectal cancer. NPJ Precis Oncol. 2023 Mar 15;7(1):28.
2. Xue Ding et al., NPM promotes hepatotoxin-induced fibrosis by inhibiting ROS-induced apoptosis of hepatic stellate cells and upregulating lncMIAT-induced TGF-β2. Cell Death Dis. 2023 Aug 30;14(8):575.
3. Wanzhou Wu et al., The TRPM7 channel reprograms cellular glycolysis to drive tumorigenesis and angiogenesis. Cell Death Dis. 2023 Mar 6;14(3):183.
4. Xiaoling Hong et al., UBE2E2 enhances Snail-mediated epithelial-mesenchymal transition and Nrf2-mediated antioxidant activity in ovarian cancer. Cell Death Dis . 2023 Feb 10;14(2):100.
5. Weimin Zhang et al., Multiple myeloma with high expression of SLC7A11 is sensitive to erastin-induced ferroptosis. Apoptosis. 2023 Nov 24.
6. Wei-Feng Hong et al., Coiled-coil domain-containing 154 promotes colorectal cancer proliferation and metastasis via interacting with minichromosome maintenance complex component 2. Cancer Lett. 2023 Dec 1:578:216460.
2. Xue Ding et al., NPM promotes hepatotoxin-induced fibrosis by inhibiting ROS-induced apoptosis of hepatic stellate cells and upregulating lncMIAT-induced TGF-β2. Cell Death Dis. 2023 Aug 30;14(8):575.
3. Wanzhou Wu et al., The TRPM7 channel reprograms cellular glycolysis to drive tumorigenesis and angiogenesis. Cell Death Dis. 2023 Mar 6;14(3):183.
4. Xiaoling Hong et al., UBE2E2 enhances Snail-mediated epithelial-mesenchymal transition and Nrf2-mediated antioxidant activity in ovarian cancer. Cell Death Dis . 2023 Feb 10;14(2):100.
5. Weimin Zhang et al., Multiple myeloma with high expression of SLC7A11 is sensitive to erastin-induced ferroptosis. Apoptosis. 2023 Nov 24.
6. Wei-Feng Hong et al., Coiled-coil domain-containing 154 promotes colorectal cancer proliferation and metastasis via interacting with minichromosome maintenance complex component 2. Cancer Lett. 2023 Dec 1:578:216460.
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Mouse STR Sample Report.pdf 附 (下载 0 次)
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Cell Line Authentication (sample).pdf 附 (下载 1 次)
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