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北京百奥莱博科技有限公司
437
多克隆抗体
YT733
多克隆
二年
Integrin β1/CD29 Rabbit Polyclonal Antibody
兔抗Integrin β1/CD29多克隆抗体抗体
兔
人,小鼠
液体
WB,FC, IHC
1mg/ml
-20℃冻存,避光
特别声明:本产品及我公司所售其他产品均为科研类试剂产品,严禁用于药物、医疗及其他非科研用途。
北京百奥莱博专注于生命科学和生物技术领域,致力于为客户提供包括YT733型兔抗Integrin β1/CD29抗体品牌在内的一系列抗体抗原产品,并提供一系列相关的技术服务。
名称:YT733型兔抗Integrin β1/CD29抗体品牌
编号:YT733
产地:国产|进口
品牌:百奥莱博
规格:50μl
英文名:Integrin β1/CD29 Rabbit Polyclonal Antibody
本品为来源于兔的抗Integrin β1/CD29的多克隆抗体。
宿主:兔
克隆性:多克隆抗体
用途:WB,FC, IHC
交叉反应性:人,小鼠
分子量:100KDa
推荐稀释比例:WB(1:500-1:1000),IHC(1:200),FC(1:100)
About this Antibody | |
Name | Integrin β1/CD29 Rabbit Polyclonal Antibody |
Category | Polyclonal antibody(pAb); Primary antibody |
Isotype | IgG |
Purification | Peptide affinity purified |
About the Immunogen | |
Immunogen | This antibody is produced by immunizing rabbits with a synthetic peptide (KLH-coupled) corresponding to CD29. |
Gene ID | 3688 |
SwissProt | P05556 |
Synonyms | CD29; FNRB; Fibronectin receptor beta subunit; ITB1; Integrin VLA-4 beta subunit; Integrin beta-1 precursor; integrin beta-1 |
Category | Adhesion/ECM |
Background | Integrins are transmembrane receptors that mediate the attachment between a cell and its surroundings, such as other cells or the extracellular matrix (ECM). Integrins are obligate heterodimers containing two distinct chains, called the α (alpha) and β (beta) subunits. The molecular mass of the integrin subunits can vary from 90 kDa to 160 kDa. Beta subunits have four cysteine-rich repeated sequences. Both α and β subunits bind several divalent cations. Integrins have two main functions: Attachment of the cell to the ECM and signal transduction from the ECM to the cell. However, they are also involved in a wide range of other biological activities, including immune patrolling, cell migration, and binding to cells by certain viruses, such as adenovirus, echovirus, hantavirus, and foot and mouth disease viruses. Research studies have implicated β1 integrin in various activities including embryonic development, blood vessel, skin, bone, and muscle formation, as well as tumor metastasis and angiogenesis. |
About this Antibody | |
Name | GRP78 Rabbit Polyclonal Antibody |
Category | Polyclonal antibody(pAb); Primary antibody |
Isotype | IgG |
Purification | Peptide affinity purified |
About the Immunogen | |
Immunogen | This antibody is produced by immunizing rabbits with a synthetic peptide (KLH-coupled) corresponding to GRP78. |
Gene ID | 3309 |
SwissProt | P11021 |
Synonyms | BIP; GLUCOSE-REGULATED PROTEIN 78-KD; HEAT-SHOCK 70-KD PROTEIN 5; IMMUNOGLOBULIN HEAVY CHAIN-BINDING PROTEIN; heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) |
Category | Protein Folding and Trafficking |
Background | Binding immunoglobulin protein (BiP) also known as 78 kDa glucose-regulated protein (GRP-78) or heat shock 70 kDa protein 5 (HSPA5) is a protein that in humans is encoded by the HSPA5 gene. BiP is a HSP70 molecular chaperone located in the lumen of the endoplasmic reticulum (ER) that binds newly synthesized proteins as they are translocated into the ER, and maintains them in a state competent for subsequent folding and oligomerization. BiP is also an essential component of the translocation machinery, as well as playing a role in retrograde transport across the ER membrane of aberrant proteins destined for degradation by the proteasome. Like many stress and heat shock proteins, BiP/GRP78 has potent immunological activity when released from the internal environment of the cell into the extracelluar space.specifically, it feeds anti-inflammatory and pro-resolutory signals into immune networks, thus helping to resolve inflammation . |
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