重组人半乳糖凝集素14(Galectin-14)厂家

特别声明：本产品及我公司所售其他产品均为科研类试剂产品，严禁用于药物、医疗及其他非科研用途。

北京百奥莱博专注于生命科学和生物技术领域，致力于为客户提供包括重组人半乳糖凝集素14(Galectin-14)厂家在内的一系列分子生物学试剂产品，并提供一系列相关的技术服务。

名称：重组人半乳糖凝集素14(Galectin-14)厂家
规格：10μg|50μg|500μg|1mg
编号：JN0728
品牌：百奥莱博
产地：国产|进口
英文名：Recombinant Human Galectin-14
本品由我们的哺乳动物细胞表达系统制备而成，目的基因编码的Met1-Asp139在C端含有His标签。

Galectin-14质量控制：＞95%(还原性SDS-PAGE)

Galectin-14制剂：液体

Galectin-14保存：收到货后请置于-20℃，可保存6个月，避免反复冻融。

关于Galectin-14：
Galectin-14 is a member of the Galectin family of carbohydrate binding proteins. The members of Galectin family contain one or two carbohydrate recognition domains, which can bind β-Galactoside. LGALS14 is expressed intracellularly in placenta and eosinophils, and is released by eosinophils following allergen stimulation. LGALS14 may be involved in the development of allergic inflammation. Two alternatively spliced transcript variants encoding distinct isoforms have been observed.

欲了解更多重组人半乳糖凝集素14(Galectin-14)厂家的品牌、产地、价格及说明书等产品信息，请致电北京百奥莱博科技有限公司，我们将竭诚为您服务，另外，以下产品正在火爆促销:

·重组小鼠IL-27
编号：JN1645
英文名称：Recombinant Mouse Interleukin-27 subunit alpha and Interleukin-27 subunit beta
规格：10μg|50μg|500μg|1mg
本品由我们的哺乳动物细胞表达系统制备而成，目的基因编码的Tyr19-Pro228&Phe29-Ser234在C端含有His标签。

IL-27质量控制：＞95%(还原性SDS-PAGE)

IL-27制剂：冻干品

IL-27保存：
冻干蛋白置于-20℃以下可长期保存，室温条件下可稳定保存3周。
复溶蛋白溶液可在4～7℃保存2～7天，可分装后置于-20℃保存三个月。

IL-27复溶：
打开试剂管前请先离心。
复溶浓度推荐大于100 μg/ml。
冻干蛋白请溶于ddH2O。
复溶后，请根据用量分装冻存，避免反复冻融。

关于IL-27：
IL-27 is a heterodimeric cytokine which belongs to the IL-6/IL-12 family of long type I cytokines. It is expressed on monocytes, endothelial cells and dendritic cells. IL-27 is an early product of activated antigen-presenting cells and drives rapid clonal expansion of naive CD4(+) T cells and plays a role in the early regulation of Th1 cells initiation which drives efficient adaptive immune response. IL-27 potentiates the early phase of TH1 response and suppresses TH2 and TH17 differentiation. It induces the differentiation of TH1 cells via two distinct pathways, p38 MAPK/TBX21- and ICAM1/ITGAL/ERK-dependent pathways. It also induces STAT1, STAT3, STAT4 and STAT5 phosphorylation and activates TBX21/T-Bet via STAT1 with resulting IL12RB2 up-regulation, an event crucial to TH1 cell commitment. IL-27 has an antiproliferative activity on melanomas through WSX-1/STAT1 signaling. Thus, IL-27 protein may be an attractive candidate as an antitumor agent applicable to cancer immunotherapy. IL-27 reveals to be a potent inhibitor of TH17 cell development and of IL-17 production. Indeed IL27 alone is also able to inhibit the production of IL17 by CD4 and CD8 T-cells. IL-27 has also an effect on cytokine production. It suppresses proinflammatory cytokine production such as IL2, IL4, IL5 and IL6 and activates suppressors of cytokine signaling such as SOCS1 and SOCS3. Apart from suppression of cytokine production, IL-27 also antagonizes the effects of some cytokines such as IL6 through direct effects on T-cells. Another important role of IL-27 is its antitumor activity as well as its antiangiogenic activity with activation of production of antiangiogenic chemokines such as IP-10/CXCL10 and MIG/CXCL9.


重组人半乳糖凝集素14(Galectin-14)厂家关键词：重组半乳糖凝集素14,JN0728,重组人半乳糖凝集素14蛋白,重组人Galectin-14


·重组人MAP1LC3A(微管结合蛋白1轻链3α)(微管相关蛋白1轻链3α)
编号：JN0920
英文名称：Recombinant Human Microtubule-Associated Protein 1 Light Chain 3 alpha
规格：10μg|50μg|500μg|1mg
本品由我们的大肠杆菌表达系统制备而成，目的基因编码的Met1-Phe121在C端含有His标签。

MAP1LC3A质量控制：＞95%(还原性SDS-PAGE)

MAP1LC3A制剂：液体

MAP1LC3A保存：收到货后请置于-20℃，可保存6个月，避免反复冻融。

关于MAP1LC3A：
Microtubule-Associated Proteins 1A/1B Light Chain 3A (MAP1LC3A) belongs to the MAP1 LC3 family. MAP1LC3A is found most abundantly in the heart, brain, liver, skeletal muscle, and testis. But it is absent in the thymus and peripheral blood leukocytes. MAP1LC3A is thought to take part in the formation of autophagosomal vacuoles and is one of the light chain subunits that functions together with both MAP1A and/or MAP1B. In addition, MAP1A has an important part in neuronal development and in maintaining the balance between neuronal plasticity and rigidity.


重组人半乳糖凝集素14(Galectin-14)厂家关键词：重组半乳糖凝集素14,JN0728,重组人半乳糖凝集素14蛋白,重组人Galectin-14

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