重组人Nectin-4(PVRL4) 重组蛋白

特别声明：本产品及我公司所售其他产品均为科研类试剂产品，严禁用于药物、医疗及其他非科研用途。

北京百奥莱博主要从事生物试剂的生产和销*(代"售")，产品线涵盖重组人Nectin-4(PVRL4) 重组蛋白在内的分子生物学试剂产品，还包括PCR及荧光定量PCR、核酸提取试剂盒类、样本核酸保护试剂、核酸提取、克隆与转化、蛋白纯化、蛋白检测、免疫组化、细胞凋亡与抗体等。

名称：重组人Nectin-4(PVRL4) 重组蛋白
编号：JN1288
英文名：Recombinant Human Poliovirus Receptor-Related Protein 4
规格：10μg|50μg|500μg|1mg
品牌：百奥莱博
本品由我们的哺乳动物细胞表达系统制备而成，目的基因编码的Gly31-Val351在C端含有His标签。

Nectin-4/PVRL4质量控制：＞95%(还原性SDS-PAGE)

Nectin-4/PVRL4制剂：冻干品

Nectin-4/PVRL4保存：
冻干蛋白置于-20℃以下可长期保存，室温条件下可稳定保存3周。
复溶蛋白溶液可在4～7℃保存2～7天，可分装后置于-20℃保存三个月。

Nectin-4/PVRL4复溶：
打开试剂管前请先离心。
复溶浓度推荐大于100 μg/ml。
冻干蛋白请溶于ddH2O。
复溶后，请根据用量分装冻存，避免反复冻融。

关于Nectin-4/PVRL4：
Nectin-4 (PVRL4) is a type I transmembrane glycoprotein which belongs to the nectin family of Ig superfamily proteins. It contains two Ig-like C2-type domains and one Ig-like V-type domain. PVRL4 seems to be involved in cell adhesion through trans-homophilic and -heterophilic interactions, the latter including specifically interactions with nectin-1. It does not act as receptor for alpha-herpesvirus entry into cells. It is predominantly expressed in placenta, the embryo and breast carcinoma. But it is not detected in normal breast epithelium. The soluble form is produced by proteolytic cleavage at the cell surface (shedding), probably by ADAM17. Mutations in this gene are the cause of ectodermal dysplasia-syndactyly syndrome type 1, an autosomal recessive disorder.

除重组人Nectin-4(PVRL4) 重组蛋白外，我公司正在打折促销以下产品：

·重组人间皮素(MPF)
编号：JN1500
英文名称：Recombinant Human Mesothelin
规格：10μg|50μg|500μg|1mg
本品由我们的哺乳动物细胞表达系统制备而成，目的基因编码的Leu37-Arg286在C端含有His标签。

MPF/Mesothelin质量控制：＞95%(还原性SDS-PAGE)

MPF/Mesothelin制剂：冻干品

MPF/Mesothelin保存：
冻干蛋白置于-20℃以下可长期保存，室温条件下可稳定保存3周。
复溶蛋白溶液可在4～7℃保存2～7天，可分装后置于-20℃保存三个月。

MPF/Mesothelin复溶：
打开试剂管前请先离心。
复溶浓度推荐大于100 μg/ml。
冻干蛋白请溶于ddH2O。
复溶后，请根据用量分装冻存，避免反复冻融。

关于MPF/Mesothelin：
Mesothelin is a cell surface glycoprotein whose expression is limited to mesothelial cells of the serosa (pleura, pericardium, and peritoneum) and epithelial cells of the trachea, tonsils, fallopian tube, and kidneys. Mesothelin plays an important role in cell survival, proliferation, migration, invasion, tumor progression, and resistance to chemotherapy. The overexpression of mesothelin can activate NF-κB and signal transducer and activator of transcription 3 (Stat3), inhibit apoptotic signaling and TNF-α-induced apoptosis, and accelerate the G1–S transition. Mesothelin is also found overexpressed in various cancers, including malignant mesothelioma, pancreatic or ovarian carcinoma, sarcomas and in some gastrointestinal or pulmonary carcinomas. As a result of its limited expression in normal tissues, mesothelin has been reported as an ideal tumor-associated marker for the development of targeted therapy.


重组人Nectin-4(PVRL4) 重组蛋白关键词：JN1288,重组人Nectin-4蛋白,重组人PVRL4,重组Nectin-4

PY02-374  *棕三甲铵琼脂基础  250克  
ARB11245 人柯萨奇病毒IgM(Cox V-IgM)ELISA代测服务 Human coxsackie virus igm,cox v-igM ELISA KIT
ARB11890 人磷酯酰肌醇特异性磷酯酶C(PIPLC)Elisa方法检测 Human phosphoinositide-specific phospholipase c,piplc ELISA KIT
F030821 BIOTIN标记兔抗山羊IgG抗体 Rabbit Anti-Goat IgG*BIOTIN
ARB10736 人纤维连接素相关抗原(FRA)ELISA代测服务 Human fibronection related antigen,fra ELISA KIT
ARB10241 人一氧化碳血红蛋白(HbCO)检测服务 Human carboxyhemoglobin,hbco ELISA KIT
ARB13672 兔半胱*酸蛋白酶抑制剂/胱抑素C(Cys-C)代做ELISA实验 Rabbit cystatin c,cys-c ELISA KIT
ARB12310 大鼠抗髓鞘相关糖蛋白抗体(MAG Ab)elisa检测操作说明书 Rat anti-myelin associated glycoprotein antibody,mag ab ELISA KIT
107021-38-5 x-α-gal
C0201 特级新生牛血清(无菌过滤)
ARB12744 小鼠Apelin 12(AP12)ELISA代测服务 Mouse apelin 12,ap12 ELISA KIT
ARB12380 大鼠乳酸脱*酶(LDH)ELISA检测服务 Rat lactate dehydrogenase,ldh ELISA KIT
ARB13043 小鼠层连蛋白/板层素(LN)酶免分析 Mouse laminin,ln ELISA KIT
ARB13640 兔子高迁移率族蛋白B1(HMGB-1)血清中含量检测 Rabbit high mobility group protein b1,hmgb-1 ELISA KIT
PAGE非变性蛋白上样缓冲液(5×)   5ml
N-乙酰神经*酸醛缩酶 Spermidine 9027-60-5
重组人Nectin-4(PVRL4) 重组蛋白关键词：JN1288,重组人Nectin-4蛋白,重组人PVRL4,重组Nectin-4


·重组人激活转录因子1(ATF1)
编号：JN0884
英文名称：Recombinant Human Activating Transcription Factor 1
规格：10μg|50μg|500μg|1mg
本品由我们的大肠杆菌表达系统制备而成，目的基因编码的Met1-Val271在C端含有His标签。

ATF1质量控制：＞95%(还原性SDS-PAGE)

ATF1制剂：冻干品

ATF1保存：
冻干蛋白置于-20℃以下可长期保存，室温条件下可稳定保存3周。
复溶蛋白溶液可在4～7℃保存2～7天，可分装后置于-20℃保存三个月。

ATF1复溶：
打开试剂管前请先离心。
复溶浓度推荐大于100 μg/ml。
冻干蛋白请溶于ddH2O。
复溶后，请根据用量分装冻存，避免反复冻融。

关于ATF1：
Cyclic AMP-dependent transcription factor ATF-1(ATF1) which contains 1 bZIP (basic-leucine zipper) domain and 1 KID (kinase-inducible) domain, belongs to the bZIP family. It influences cellular physiologic processes by regulating the expression of downstream target genes, which are related to growth, survival, and other cellular activities. ATF1 binds the cAMP response element (CRE) (consensus: 5-GTGACGT[AC][AG]-3), a sequence present in many viral and cellular promoters. It also binds to the Tax-responsive element (TRE) of HTLV-I. ATF1 mediates PKA-induced stimulation of CRE-reporter genes, represses the expression of FTH1 and other antioxidant detoxification genes, triggers cell proliferation and transformation. ATF1 is phosphorylated at serine 63 in its kinase-inducible domain by serine/threonine kinases, cAMP-dependent protein kinase A, calmodulin-dependent protein kinase I/II, mitogen- and stress-activated protein kinase and CDK3. Its phosphorylation enhances its transactivation and transcriptional activities, and enhances cell transformation.

我公司正在火爆促销重组蛋白系列产品，欢迎您的垂询选购重组人Nectin-4(PVRL4) 重组蛋白。