北京现货重组小鼠趋化因子CXCL12(SDF-1)优惠

特别声明：本产品及我公司所售其他产品均为科研类试剂产品，严禁用于药物、医疗及其他非科研用途。

北京百奥莱博专注于生命科学和生物技术领域，致力于为客户提供包括北京现货重组小鼠趋化因子CXCL12(SDF-1)优惠在内的一系列分子生物学试剂产品，并提供一系列相关的技术服务。

名称：北京现货重组小鼠趋化因子CXCL12(SDF-1)优惠
产地：国产|进口
英文名：Recombinant Mouse C-X-C motif chemokine 12
品牌：百奥莱博
编号：JN0321
本品由我们的大肠杆菌表达系统制备，目的基因编码的Lys22-Lys89表达纯化而来。

CXCL12/SDF-1质量控制：＞95%(还原性SDS-PAGE)。

CXCL12/SDF-1制剂：冻干品

CXCL12/SDF-1保存：
冻干蛋白可在-20℃长期保存，室温也可稳定保存3周。
复溶蛋白溶液可在4～7℃保存2～7天。
复溶后建议分装冻存在-20℃，可保存3个月，应避免反复冻融。

CXCL12/SDF-1复溶：
1、试剂开盖前请先离心。
2、复溶浓度应大于100 μg/ml.
3、冻干蛋白溶于ddH2O中
4、复溶后根据使用量分装保存，避免反复冻融。

关于CXCL12/SDF-1：
Mouse Cxcl12 is a secreted and highly conserved protein which belongs to the intercrine alpha (chemokine CxC) family.CXCL12 is widely expressed in various organs including brain, kidney, skeletal muscle, heart, liver, and lymphoid organs. Cxcl12 activates the C-X-C chemokine receptor CXCR4 to induce a rapid and transient rise in the level of intracellular calcium ions and chemotaxis. It also binds to atypical chemokine receptor ACKR3 which activates the beta-arrestin pathway and acts as a scavenger receptor for SDF-1. Cxcl12 has several critical functions during embryonic development such as B-cell lymphopoiesis, myelopoiesis in bone marrow and heart ventricular septum formation. Cxcl12 plays an important role in acting as a positive regulator of monocyte migration and a negative regulator of monocyte adhesion via the LYN kinase. It stimulates migration of monocytes and T-lymphocytes through its receptors, CXCR4 and ACKR3, and decreases monocyte adherence to surfaces coated with ICAM-1, a ligand for beta-2 integrins. SDF1A/CXCR4 signaling axis inhibits beta-2 integrin LFA-1 mediated adhesion of monocytes to ICAM-1 through LYN kinase. It also plays a protective role after myocardial infarction, induces down-regulation and internalization of ACKR3 expressed in various cells and stimulates the proliferation of bone marrow-derived b progenitor cells in the presence of IL-7 as well as growth of the stromal cell-dependent B-cell clone DW34 cells.

北京现货重组小鼠趋化因子CXCL12(SDF-1)优惠极具性价比，此外，我公司正火爆促销以下产品：

·重组小鼠B7-1(CD80)
编号：JN1445
英文名称：Recombinant Mouse Activation B7-1 antigen
规格：10μg|50μg|500μg|1mg
本品由我们的哺乳动物细胞表达系统制备而成，目的基因编码的Val38-Lys245在C端带有Fc标签。

B7-1/CD80 质量控制：＞95%(还原性SDS-PAGE)

B7-1/CD80 制剂：冻干品

B7-1/CD80 保存：
冻干蛋白置于-20℃以下可长期保存，室温条件下可稳定保存3周。
复溶蛋白溶液可在4～7℃保存2～7天，可分装后置于-20℃保存三个月。

B7-1/CD80 复溶：
打开试剂管前请先离心。
复溶浓度推荐大于100 μg/ml。
冻干蛋白请溶于ddH2O。
复溶后，请根据用量分装冻存，避免反复冻融。

关于B7-1/CD80 ：
Cluster of Differentiation 80, also called B7-1, is a member of cell surface immunoglobulin superfamily which plays key, yet distinct roles in the activation of T cells. It is the ligand for two different proteins on the T cell surface: CD28 and CTLA-4. Studies have shown that CTLA-4 binds mostly to CD80. The structure presents two extracellular domains: a membrane distal variable-like domain (IgV) and a membrane proximal Ig constant-like domain (IgC) along with an intracellular domain. Both IgV and IgC consist of anti-parallel beta sandwiches joined by a short linker region. CD80 is mostly expressed on the surface of antigen-presenting cells including activated B cells, macrophages and dendritic cells.


北京现货重组小鼠趋化因子CXCL12(SDF-1)优惠关键词：重组小鼠趋化因子CXCL12蛋白,重组小鼠SDF-1,JN0321,重组趋化因子CXCL12


·重组人ECH1
编号：JN1388
英文名称：Recombinant Human Delta(3,5)-Delta(2,4)-dienoyl-CoA isomerase, mitochondrial
规格：10μg|50μg|500μg|1mg
本品由我们的大肠杆菌表达系统制备而成，目的基因编码的Thr34-Leu328在N端含有His标签。

ECH1质量控制：＞95%(还原性SDS-PAGE)

ECH1制剂：液体

ECH1保存：收到货后请置于-20℃，可保存6个月，避免反复冻融。

关于ECH1：
Human delta(3,5)-Delta(2,4)-dienoyl-CoA isomerase(ECH1) is a member of the hydratase/isomerase superfamily and contains a C-terminal peroxisomal targeting sequence and localizes to peroxisomes. ECH1 shows high sequence similarity to enoyl-CoA hydratases of several species, particularly within a conserved domain characteristic of these proteins. The rat orthologlocalizes to the matrix of both the peroxisome and mitochondria.It can isomerize 3-trans, 5-cis-dienoyl-CoA to 2-trans,4-trans-dienoyl-CoA, indicating that it is a delta3,5-delta2,4-dienoyl-CoA isomerase. ECH1 plays an important role in the auxiliary step of the fatty acid beta-oxidation pathway.


北京现货重组小鼠趋化因子CXCL12(SDF-1)优惠关键词：重组小鼠趋化因子CXCL12蛋白,重组小鼠SDF-1,JN0321,重组趋化因子CXCL12

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我公司正在打折促销重组蛋白全系列产品，恭候您的咨询选购北京现货重组小鼠趋化因子CXCL12(SDF-1)优惠。