北京现货重组小鼠成纤维生长因子9批发

特别声明：本产品及我公司所售其他产品均为科研类试剂产品，严禁用于药物、医疗及其他非科研用途。

北京百奥莱博专业生产销*(代"售")北京现货重组小鼠成纤维生长因子9批发，我公司供应的分子生物学试剂品类齐全，且具有优势价格，欢迎新老客户垂询订购。

名称：北京现货重组小鼠成纤维生长因子9批发
品牌：百奥莱博
产地：国产|进口
英文名：Recombinant Mouse Fibroblast Growth Factor 9
规格：10μg|50μg|500μg|1mg
本品由我们的大肠杆菌表达系统制备，目的基因编码的Met1­Ser208在C端含有His标签。

FGF-9质量控制：＞95%(还原性SDS-PAGE)。

FGF-9制剂：液体

FGF-9保存：
收到后请置于-20℃，可稳定保存6个月，避免反复冻融。

关于FGF-9：
Fibroblast growth factor-9 (FGF-9) is an approximately 26 kDa secreted glycoprotein of the FGF family. Secreted mouse FGF-9 lacks the N-terminal 1-3 aa and shares >98% sequence identity with rat, human, equine, porcine and bovine FGF-9. FGF-9 plays an important role in the regulation of embryonic development, cell proliferation, cell differentiation and cell migration. In the mouse embryo the location and timing of FGF-9 expression affects development of the skeleton, cerebellum, lungs, heart, vasculature, digestive tract, and testes .It may have a role in glial cell growth and differentiation during development, gliosis during repair and regeneration of brain tissue after damage, differentiation and survival of neuronal cells, and growth stimulation of glial tumors. Deletion of mouse FGF-9 is lethal at birth due to lung hypoplasia, and causes rhizomelia, or shortening of the proximal skeleton. An unusual constitutive dimerization of FGF 9 buries receptor interaction sites which lowers its activity, and increases heparin affinity which inhibits diffusion. A spontaneous mouse mutant, Eks, interferes with dimerization, resulting monomeric, diffusible FGF-9 that causes elbow and knee synostoses (joint fusions) due to FGF-9 misexpression in developing joints.

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北京现货重组小鼠成纤维生长因子9批发关键词：重组成纤维生长因子9,Recombinant Mouse Fibroblast Growth Factor 9,重组小鼠成纤维生长因子9蛋白,百奥莱博,JN0283

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北京现货重组小鼠成纤维生长因子9批发关键词：重组成纤维生长因子9,Recombinant Mouse Fibroblast Growth Factor 9,重组小鼠成纤维生长因子9蛋白,百奥莱博,JN0283


·重组人Mesothelin(间皮蛋白)
编号：JN1581
英文名称：Recombinant Human Mesothelin
规格：10μg|50μg|500μg|1mg
本品由我们的哺乳动物细胞表达系统制备而成，目的基因编码的Glu296-Ser598在C端含有His标签。

Mesothelin质量控制：＞95%(还原性SDS-PAGE)

Mesothelin制剂：冻干品

Mesothelin保存：
冻干蛋白置于-20℃以下可长期保存，室温条件下可稳定保存3周。
复溶蛋白溶液可在4～7℃保存2～7天，可分装后置于-20℃保存三个月。

Mesothelin复溶：
打开试剂管前请先离心。
复溶浓度推荐大于100 μg/ml。
冻干蛋白请溶于ddH2O。
复溶后，请根据用量分装冻存，避免反复冻融。

关于Mesothelin：
Mesothelin is a cell surface glycoprotein whose expression is limited to mesothelial cells of the serosa (pleura, pericardium, and peritoneum) and epithelial cells of the trachea, tonsils, fallopian tube, and kidneys. Mesothelin plays an important role in cell survival, proliferation, migration, invasion, tumor progression, and resistance to chemotherapy. The overexpression of mesothelin can activate NF-κB and signal transducer and activator of transcription 3 (Stat3), inhibit apoptotic signaling and TNF-α-induced apoptosis, and accelerate the G1–S transition. Mesothelin is also found overexpressed in various cancers, including malignant mesothelioma, pancreatic or ovarian carcinoma, sarcomas and in some gastrointestinal or pulmonary carcinomas. As a result of its limited expression in normal tissues, mesothelin has been reported as an ideal tumor-associated marker for the development of targeted therapy.

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