JN0547型重组人u-Plasminogen Activa

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JN0547型重组人u-Plasminogen Activator厂商由专业试剂供应商北京百奥莱博提供，用于生化研究，本产品质量好，且极具价格优势，深为用户称道，了解更多重组人u-Plasminogen Activator等重组蛋白产品请联*(代"系")我司咨询订购。

名称：JN0547型重组人u-Plasminogen Activator厂商
编号：JN0547
产地：国产|进口
规格：10μg|50μg|500μg|1mg
英文名：Recombinant Human Urokinase-Type Plasminogen Activator
本品由我们的哺乳动物细胞表达系统制备而成，目的基因编码的Ser21-Leu431在C端含有His标签。

u-Plasminogen Activator质量控制：＞95%(还原性SDS-PAGE)

u-Plasminogen Activator制剂：液体

u-Plasminogen Activator保存：收到货后请置于-20℃，可保存6个月，避免反复冻融。

关于u-Plasminogen Activator：
Recombinant Human Urokinase-Type Plasminogen Activator is a serine protease, which specifically cleaves the zymogen plasminogen to form the active enzyme plasmin. Urokinase-Type Plasminogen Activator is a potent marker of invasion and metastasis in many human cancers associated with breast, colon, stomach, bladder, brain, ovary and endometrium. Human Urokinase-Type Plasminogen Activator is initially synthesized as 431 amino acid precursor with a N-terminal signal peptide residues. The single chain molecule is processed into a disulfide-linked two-chain molecule. There exists two forms A chain, the long A chain contains an EGF-like domain that is responsible for binding of the uPA receptor. The B chain corresponds to the catalytic domain.


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·重组人G6PD(葡萄糖-6-磷酸1-脱*酶)
编号：JN0734
英文名称：Recombinant Human Glucose-6-Phosphate 1-Dehydrogenase
规格：10μg|50μg|500μg|1mg
本品由我们的哺乳动物细胞表达系统制备而成，目的基因编码的Ala2-Leu515在C端含有His标签。

G6PD质量控制：＞95%(还原性SDS-PAGE)

G6PD制剂：液体

G6PD保存：收到货后请置于-20℃，可保存6个月，避免反复冻融。

关于G6PD：
Glucose-6-Phosphate 1-Dehydrogenase (G6PD) is a cytosolic enzyme that belongs to the glucose-6-phosphate dehydrogenase family. G6PD participates in the pentose phosphate pathway that supplies reducing energy to cells by maintaining the level of the co-enzyme nicotinamide adenine dinucleotide phosphate (NADPH). G6PD produces pentose sugars for nucleic acid synthesis and main producer of NADPH reducing power. NADPH in turn maintains the level of glutathione in these cells that helps protect the red blood cells against oxidative damage. It is notable in humans that G6PD is remarkable for its genetic diversity. G6PD deficiency may cause neonatal jaundice, acute hemolysis, or severe chronic non-spherocytic hemolytic anemia.


JN0547型重组人u-Plasminogen Activator厂商关键词：Recombinant Human Urokinase-Type Plasminogen Activ,百奥莱博,重组人u-Plasminogen Activator蛋白,重组u-Plasminogen Activator,JN0547


·重组小鼠EDA2R(TNFRSF27)(XEDAR)
编号：JN0493
英文名称：Recombinant Mouse Ectodysplasin A2 Receptor
规格：10μg|50μg|500μg|1mg
本品由我们的哺乳动物细胞表达系统制备而成，目的基因编码的Met1-Thr138在C端含有His标签。

EDA2R/TNFRSF27/XEDAR 质量控制：＞95%(还原性SDS-PAGE)

EDA2R/TNFRSF27/XEDAR 制剂：冻干品

EDA2R/TNFRSF27/XEDAR 保存：
冻干蛋白置于-20℃以下可长期保存，室温条件下可稳定保存3周。
复溶蛋白溶液可在4～7℃保存2～7天，可分装后置于-20℃保存三个月。

EDA2R/TNFRSF27/XEDAR 复溶：
打开试剂管前请先离心。
复溶浓度推荐大于100 μg/ml。
冻干蛋白请溶于ddH2O。
复溶后，请根据用量分装冻存，避免反复冻融。

关于EDA2R/TNFRSF27/XEDAR ：
Tumor necrosis factor receptor superfamily member 27, also known as XEDAR and EDA2R, is a type III transmembrane protein of the TNFR superfamily. EDA2R consists of extracellular domain (ECD) with 3 cysteine-rich repeats and a single transmembrane domain but lacks an N-terminal signal peptide. EDA2R is widely expressed, notably in embryonic basal epidermal cells and maturing hair follicles. Even though it does not contain a cytoplasmic death domain, EDA2R can associate with Fas and induce EDA‑A2 dependent apoptosis. Its transcription is directly induced by p53, and it mediated cell death is p53 dependent. it is down‑regulated in breast, colon, and lung cancers, particularly in cases with p53 mutations. It also plays a role in EDA‑A2 induced skeletal muscle degeneration and osteoblast differentiation. Mutations in the EDA gene are associated with the X-linked form of Hypohidrotic Ectodermal Dysplasia (HED), a disease typically characterized by abnormal hair, teeth and sweat glands.


JN0547型重组人u-Plasminogen Activator厂商关键词：Recombinant Human Urokinase-Type Plasminogen Activ,百奥莱博,重组人u-Plasminogen Activator蛋白,重组u-Plasminogen Activator,JN0547

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