重组人Serpin B9(丝氨酸蛋白酶抑制剂B9)价格

特别声明：本产品及我公司所售其他产品均为科研类试剂产品，严禁用于药物、医疗及其他非科研用途。

北京百奥莱博专注于生命科学和生物技术领域，致力于为客户提供包括重组人Serpin B9(丝*酸蛋白酶抑制剂B9)价格在内的一系列分子生物学试剂产品，并提供一系列相关的技术服务。

名称：重组人Serpin B9(丝*酸蛋白酶抑制剂B9)价格
编号：JN1303
规格：10μg|50μg|500μg|1mg
英文名：Recombinant Human Serine Protease Inhibitor-clade B9
产地：国产|进口
本品由我们的哺乳动物细胞表达系统制备而成，目的基因编码的Met1-Pro376在C端含有His标签。

Serpin B9质量控制：＞95%(还原性SDS-PAGE)

Serpin B9制剂：冻干品

Serpin B9保存：
冻干蛋白置于-20℃以下可长期保存，室温条件下可稳定保存3周。
复溶蛋白溶液可在4～7℃保存2～7天，可分装后置于-20℃保存三个月。

Serpin B9复溶：
打开试剂管前请先离心。
复溶浓度推荐大于100 μg/ml。
冻干蛋白请溶于ddH2O。
复溶后，请根据用量分装冻存，避免反复冻融。

关于Serpin B9：
Serpin B9, also known as Cytoplasmic antiproteinase 3(CAP-3), is a cytoplasm protein which belongs to the large superfamily of serine proteinase inhibitors (serpins), which bind to and inactivate serine proteinases.Serpin B9 is an inhibitor of the granzyme B/perforin lytic pathway. It is expressed in normal mammary epithelial cells but not in most mammary carcinoma cell lines. These interactions are involved in many cellular processes, including coagulation, fibrinolysis, complement fixation, matrix remodeling, and apoptosis. Serpin-B9 expression in immune-privileged cells, APCs, and CTLs protects these cells against the actions of granzyme B, and when expressed in tumor cells or virally infected hepatocytes, confers resistance to killing by CTL and NK cells. Expression of increasing levels of Serpin-B9 in target cells may progressively inhibit immune surveillance by blocking NK and CTL-induced cytotoxicity through the perforin / granzyme pathway and then through the Fas / FasL pathway.

我公司的重组人Serpin B9(丝*酸蛋白酶抑制剂B9)价格，性价比高，货期短，送货上门，欢迎您来电咨询购买，另外，我公司还生产供应销*(代"售")下列产品：

·重组人BH3结构域凋亡诱导蛋白(BID)
编号：JN1912
英文名称：Recombinant Human BH3-Interacting Domain Death Agonist
规格：10μg|50μg|500μg|1mg
本品由我们的大肠杆菌表达系统制备而成，目的基因编码的Met1-Asp195表达纯化得来。

BID/BH3-interacting domain death agonist质量控制：＞95%(还原性SDS-PAGE)

BID/BH3-interacting domain death agonist制剂：液体

BID/BH3-interacting domain death agonist保存：收到货后请置于-20℃，可保存6个月，避免反复冻融。

关于BID/BH3-interacting domain death agonist：
BH3-Interacting Domain Death Agonist (BID) is a member of the Bcl-2 protein family which regulates outer mitochondrial membrane permeability. BID is a pro-apoptotic member that causes cytochrome c to be released from the mitochondria intermembrane space into the cytosol. Interaction of Bid with Bak causes altered mitochondrial membrane permeability. BID contains only the BH3 domain, which is required for its interaction with the Bcl-2 family proteins and for its pro-death activity. BID is susceptible to proteolytic cleavage by caspases, calpains, Granzyme B and cathepsins. It is an integrating key regulator of the intrinsic death pathway that amplifies caspase-dependent and caspase-independent execution of neuronal apoptosis. Therefore pharmacological inhibition of BID provides a promising therapeutic strategy in neurological diseases where programmed cell death is prominent, and also offer a new strategy for the treatment of acute renal failure associated with ischemia-reperfusion. BID receives direct inputs from a key regulator of the cell cycle arrest/DNA repair machinery (ATM), and therefore is an excellent candidate to coordinate genotoxic stress responses and apoptotic cell death. BID is a novel pro-apoptosis Bcl-2 family protein that is activated by caspase 8 in response to Fas/TNF-R1 death receptor signals. Deletion of BID inhibits carcinogenesis in the liver, although this genetic alteration promotes tumorigenesis in the myeloid cells. This is likely related to the function of BID to promote cell cycle progression into S phase. BID could be also involved in the maintenance of genomic stability by engaging at mitosis checkpoint.


重组人Serpin B9(丝*酸蛋白酶抑制剂B9)价格关键词：重组人丝*酸蛋白酶抑制剂B9,重组人Serpin B9蛋白,重组Serpin B9,JN1303


·重组人胶质细胞源性神经营养因受体α2(GFRA2)
编号：JN1301
英文名称：Recombinant Human Glial Cell line-derived Neurotrophic Factor Receptor alpha 2
规格：10μg|50μg|500μg|1mg
本品由我们的哺乳动物细胞表达系统制备而成，目的基因编码的Ser22-Ser441在C端含有Fc标签和His标签

GFRA2质量控制：＞95%(还原性SDS-PAGE)

GFRA2制剂：冻干品

GFRA2保存：
冻干蛋白置于-20℃以下可长期保存，室温条件下可稳定保存3周。
复溶蛋白溶液可在4～7℃保存2～7天，可分装后置于-20℃保存三个月。

GFRA2复溶：
打开试剂管前请先离心。
复溶浓度推荐大于100 μg/ml。
冻干蛋白请溶于ddH2O。
复溶后，请根据用量分装冻存，避免反复冻融。

关于GFRA2：
GDNF family receptor alpha-2 is a glycosylphosphatidylinosito l (GPI)-linked cell surface receptor. It is part of the GDNF receptor family. Glial cell line-derived neurotrophic factor (GDNF) and neurturin (NTN) are two structurally related, potent neurotrophic factors that play key roles in the control of neuron survival and differentiation. GFRA2 mediates the NRTN-induced autophosphorylation and activation of the RET receptor. It also able to mediate GDNF signaling through the RET tyrosine kinase receptor. It acts preferentially as a receptor for NTN comp*(代"a")red to its other family member, GDNF family receptor alpha 1.


重组人Serpin B9(丝*酸蛋白酶抑制剂B9)价格关键词：重组人丝*酸蛋白酶抑制剂B9,重组人Serpin B9蛋白,重组Serpin B9,JN1303

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我公司强烈推荐重组蛋白系列产品，热情期待您的咨询选购重组人Serpin B9(丝*酸蛋白酶抑制剂B9)价格。