重组人白介素IL-20(白细胞介素20)厂商

特别声明：本产品及我公司所售其他产品均为科研类试剂产品，严禁用于药物、医疗及其他非科研用途。

北京百奥莱博专注于生命科学和生物技术领域，致力于为客户提供包括重组人白介素IL-20(白细胞介素20)厂商在内的一系列分子生物学试剂产品，并提供一系列相关的技术服务。

名称：重组人白介素IL-20(白细胞介素20)厂商
品牌：百奥莱博
产地：国产|进口
编号：JN0356
规格：10μg|50μg|500μg|1mg
英文名：Recombinant Human Interleukin-20
本品由我们的大肠杆菌表达系统制备，目的基因编码的Leu25-Glu176表达纯化而来。

IL-20质量控制：＞95%(还原性SDS-PAGE)。

IL-20制剂：冻干品

IL-20保存：
冻干蛋白可在-20℃长期保存，室温也可稳定保存3周。
复溶蛋白溶液可在4～7℃保存2～7天。
复溶后建议分装冻存在-20℃，可保存3个月，应避免反复冻融。

IL-20复溶：
1、试剂开盖前请先离心。
2、复溶浓度应大于100 μg/ml.
3、冻干蛋白溶于ddH2O中
4、复溶后根据使用量分装保存，避免反复冻融。

关于IL-20：
Interleukin-20 (IL-20) is a member of the IL-10 family of regulatory cytokines that includes IL-10, IL-19, IL-20, IL-22, IL-24 and IL-26. Members of this family share partial homology in their amino acid sequences but they are dissimilar in their biological functions. IL-20 exhibits approximately 28% amino acid identity with IL-10 and 76% amino acid identity with mouse IL-20. There are two heterodimeric receptor complexes for IL-20. The first is composed of IL-20 Rα and IL-20 Rβ. The second is composed of IL-22 R and IL-20 Rβ. Whereas the IL-22 R/IL-20 Rβ complex is shared with IL-24, the IL-20 Rα/IL-20 Rβ complex is shared with both IL-19 and IL-24. IL-20 has been shown to initiate transduction cascades involving STAT3 and stimulates the induction of pro-inflammatory genes including TNF-α and MCP-1. Initial functional studies using transgenic mice suggest that IL-20 has the ability to regulate skin development. The over-expression of both human and mouse forms of IL-20 results in keratinocyte hyper-proliferation, abnormal epidermal differentiation, and neonatal lethality. In humans, IL-20 and its receptors are up-regulated in psoriatic skin, and polymorphisms in the IL-20 gene have been associated with plaque-type psoriasis. IL-20 may also have a role in hematopoiesis. It enhances the proliferation of multi-potential progenitors in vitro and increases their numbers and cell cycling status in IL-20 transgenic mice. IL-20 is also shown to suppress COX-2 and PGE2 and acts as an inhibitor of angiogenesis in model systems.

除重组人白介素IL-20(白细胞介素20)厂商外，我公司正在打折促销以下产品：

·重组人NAD激酶(NADK)
编号：JN0672
英文名称：Recombinant Human NAD Kinase
规格：10μg|50μg|500μg|1mg
本品由我们的大肠杆菌表达系统制备而成，目的基因编码的Ser64-Gly446在N端含有His标签。

NADK质量控制：＞95%(还原性SDS-PAGE)

NADK制剂：液体

NADK保存：收到货后请置于-20℃，可保存6个月，避免反复冻融。

关于NADK：
NAD Kinase (NADK) is an enzyme that belongs to the NAD Kinase family. It is a widely expressed enzyme, but it is not detected in skeletal muscle. NADK converts Nicotinamide Adenine Dinucleotide (NAD+) into NADP+, through phosphorylating the NAD+ coenzyme. NADP+ is an essential coenzyme in metabolism and provides reducing power to biosynthetic processes such as fatty acid biosynthesis. The structure of the NADK from the archaean Archaeoglobus fulgidus has been determined.

·重组人TNFRSF1A
编号：JN0471
英文名称：Recombinant Human Tumor Necrosis Factor Receptor I
规格：10μg|50μg|500μg|1mg
本品由我们的大肠杆菌表达系统制备而成，目的基因编码的Ile22-Thr211在N端含有His标签。

TNFRSF1A质量控制：＞95%(还原性SDS-PAGE)

TNFRSF1A制剂：冻干品

TNFRSF1A保存：
冻干蛋白置于-20℃以下可长期保存，室温条件下可稳定保存3周。
复溶蛋白溶液可在4～7℃保存2～7天，可分装后置于-20℃保存三个月。

TNFRSF1A复溶：
打开试剂管前请先离心。
复溶浓度推荐大于100 μg/ml。
冻干蛋白请溶于ddH2O。
复溶后，请根据用量分装冻存，避免反复冻融。

关于TNFRSF1A：
Tumor necrosis factor receptor superfamily member 1A (Tnfrsf1a) is a member of the tumor necrosis factor receptor superfamily. Tnfrsf1a is one of the major receptors for the tumor necrosis factor-alpha. It can activate the transcription factor NF-κB, mediate apoptosis, and function as a regulator of inflammation. Antiapoptotic protein BCL2-associated athanogene 4 (BAG4/SODD) and adaptor proteins TRADD and TRAF2 have been shown to interact with this receptor, and thus play regulatory roles in the signal transduction mediated by the receptor. Germline mutations of the extracellular domains of this receptor were found to be associated with the human genetic disorder called tumor necrosis factor associated periodic syndrome (TRAPS) or periodic fever syndrome


重组人白介素IL-20(白细胞介素20)厂商关键词：JN0356,重组白介素IL-20,重组人白介素IL-20蛋白,重组人白细胞介素20


·重组人NKG2A(CD159A)(KLRC1)
编号：JN0945
英文名称：Recombinant Human NKG2-A/NKG2-B Type II Integral Membrane Protein
规格：10μg|50μg|500μg|1mg
本品由我们的哺乳动物细胞表达系统制备而成，目的基因编码的Arg100-Leu233 在N端带有His标签。

NKG2A/CD159A/KLRC1质量控制：＞95%(还原性SDS-PAGE)

NKG2A/CD159A/KLRC1制剂：冻干品

NKG2A/CD159A/KLRC1保存：
冻干蛋白置于-20℃以下可长期保存，室温条件下可稳定保存3周。
复溶蛋白溶液可在4～7℃保存2～7天，可分装后置于-20℃保存三个月。

NKG2A/CD159A/KLRC1复溶：
打开试剂管前请先离心。
复溶浓度推荐大于100 μg/ml。
冻干蛋白请溶于ddH2O。
复溶后，请根据用量分装冻存，避免反复冻融。

关于NKG2A/CD159A/KLRC1：
NKG2-A/NKG2-B Type II Integral Membrane Protein contains 1 C-type lectin domain and belongs to the killer cell lectin-like receptor family. The killer cell lectin-like receptor family is a group of transmembrane proteins preferentially expressed in NK cells. Members of this proteins is characterized by the type II membrane orientation and the presence of a C-type lectin domain. NKG2 is expressed only in NK-cells, but not in T-cells or B-cells. It has been shown that NKG2 represents a family of related cDNA clones, designated NKG2A, NKG2B, NKG2C, and NKG2D, which encode type 2 integral membrane proteins (extracellular C-terminus) containing a C-type lectin domain. NKG2 plays a role as a receptor for the recognition of MHC class I HLA-E molecules by NK cells and some cytotoxic T-cells. NKG2A and NKG2B have been given the designation CD159a in the nomenclature of CD antigens.


重组人白介素IL-20(白细胞介素20)厂商关键词：JN0356,重组白介素IL-20,重组人白介素IL-20蛋白,重组人白细胞介素20


·重组人β-Galactosidase(β半乳糖苷酶)
编号：JN1697
英文名称：Recombinant Human beta-Galactosidase
规格：10μg|50μg|500μg|1mg
本品由我们的哺乳动物细胞表达系统制备而成，目的基因编码的Leu24-Val677在C端含有His标签。

β-Galactosidase质量控制：＞95%(还原性SDS-PAGE)

β-Galactosidase制剂：液体

β-Galactosidase保存：收到货后请置于-20℃，可保存6个月，避免反复冻融。

关于β-Galactosidase：
β Galactosidase is a lysosomal β Galactosidase that hydrolyzes the terminal β Galactose from Ganglioside and Keratan sulfate. In lysosome, the mature β Galactosidase protein associates with Cathepsin A and Neuraminidase 1 to form the lysosomal multienzyme complex . An alternative splicing at the RNA level of β Galactosidase results a catalytically inactive β Galactosidase that plays an important role in vascular development. Defects of β-galactosidase (GLB1) are the cause of diseases like GM1-gangliosidosis which is a lysosomal storage disease and Morquio Syndrome B that cause patients to have abnormal elastic fibers. More than 100 mutations have been identified for β Galactosidase, which result in different residual activities of the mutant enzymes and a spectrum of symptoms in the two related diseases.

我公司正在火爆促销重组蛋白系列产品，欢迎您的垂询选购重组人白介素IL-20(白细胞介素20)厂商。