重组小鼠内皮细胞特异性分子1(Endocan)打折促销

特别声明：本产品及我公司所售其他产品均为科研类试剂产品，严禁用于药物、医疗及其他非科研用途。

北京百奥莱博专业生产供应重组小鼠内皮细胞特异性分子1(Endo*(代"c")an)打折促销，我公司销*(代"售")全品类的分子生物学试剂，价格优惠，欢迎广大科研工作者垂询订购。

名称：重组小鼠内皮细胞特异性分子1(Endo*(代"c")an)打折促销
规格：10μg|50μg|500μg|1mg
编号：JN1497
产地：国产|进口
品牌：百奥莱博
英文名：Recombinant Mouse Endothelial cell-specific molecule 1
本品由我们的哺乳动物细胞表达系统制备而成，目的基因编码的Trp20-Arg184在C端含有His标签。

Endo*(代"c")an 质量控制：＞95%(还原性SDS-PAGE)

Endo*(代"c")an 制剂：冻干品

Endo*(代"c")an 保存：
冻干蛋白置于-20℃以下可长期保存，室温条件下可稳定保存3周。
复溶蛋白溶液可在4～7℃保存2～7天，可分装后置于-20℃保存三个月。

Endo*(代"c")an 复溶：
打开试剂管前请先离心。
复溶浓度推荐大于100 μg/ml。
冻干蛋白请溶于ddH2O。
复溶后，请根据用量分装冻存，避免反复冻融。

关于Endo*(代"c")an ：
Endothelial cell-specific molecule–1 (ESM-1)—so-called endo*(代"c")an—is a novel endothelium derived soluble dermatan sulfate proteoglycan (PG) that is constitutively expressed by endothelial cells in lungs and kidneys and can be detected in human blood. It is encoded by the ESM1 gene. The expression of this gene is regulated by several cytokines and growth factors, such as vascular endothelial growth factor. Inflammatory cytokines, such as interleukin (IL)-1β and tumor necrosis factor (TNF)-α, stimulate the upregulation of endo*(代"c")an mRNA and the secretion of endo*(代"c")an from endothelial cells. The binding of circulating endo*(代"c")an to leukocyte ligand for ICAM-1—Lymphocyte Function-associated Antigen-1 (LFA-1) and to leukocyte ligand for VCAM-1—Very Late Antigen-4 (VLA-4) is important in leukocyte adhesion and interaction with activated endothelium. Endo*(代"c")an is a key player in the regulation of major processes such as cell adhesion in inflammatory disorders and tumor progression.

关于重组小鼠内皮细胞特异性分子1(Endo*(代"c")an)打折促销的更详细说明，请致电我公司咨询，我们将以最饱满的热情为您提供解答，此外，我公司专业供应下列产品：

·重组人BAMBI
编号：JN0626
英文名称：Recombinant Human BMP and Activin Membrane-Bound Inhibitor Homolog/BAMBI
规格：10μg|50μg|500μg|1mg
本品由我们的哺乳动物表达系统制备而成(人类细胞)。目的蛋白包含序列(Val21-Ala152)在C端含有His标签。

BAMBI质量控制：＞95%(SEC-HPLC，还原性SDS-PAGE)


BAMBI制剂：冻干品

BAMBI保存：
冻干蛋白长期保存应置于-20℃以下，常温可稳定保存3周。
复溶蛋白溶液可在4℃保存2～7天。
复溶后的蛋白溶液应尽量避免反复冻融，可根据使用量分装冻存在-20℃以下长达3个月。

BAMBI复溶：
打开试剂管前请先离心。
复溶浓度推荐大于100 μg/ml。
Dissolve the lyophilized protein in 1X PBS.
复溶后，请根据用量分装冻存，避免反复冻融。

关于BAMBI：
BMP and Activin Membrane-Bound Inhibitor Homolog (BAMBI) is a single-pass type I membrane protein that belongs to the BAMBI family. BAMBI is highly expression in kidney medulla, placenta and spleen. BAMBI is induced by BMP signaling through the evolutionary conserved BMP-responsive elements in its promoter. BAMBI plays important roles in signal transduction in many developmental and pathological processes. BAMBI transcription is activated by Wnt/beta-catenin signaling then its expression is aberrantly elevated in most colorectal carcinomas. BAMBI stably associates with TGF-β-family receptors and inhibits BMP and activin as well as TGF-β signalling. BAMBI negatively regulates TGF-β-family signalling by a regulatory mechanism involving the interaction of signalling receptors with a pseudoreceptor.


重组小鼠内皮细胞特异性分子1(Endo*(代"c")an)打折促销关键词：重组小鼠内皮细胞特异性分子1,重组小鼠Endo*(代"c")an,重组内皮细胞特异性分子1,JN1497,重组小鼠内皮细胞特异性分子1蛋白


·重组人信号转导与转录激活因子1(STAT1)
编号：JN0935
英文名称：Recombinant Human Signal Transducer and Activator of Transcription 1
规格：10μg|50μg|500μg|1mg
本品由我们的大肠杆菌表达系统制备而成，目的基因编码的Met1-Val712表达纯化得来。

STAT1质量控制：＞95%(还原性SDS-PAGE)

STAT1制剂：冻干品

STAT1保存：
冻干蛋白置于-20℃以下可长期保存，室温条件下可稳定保存3周。
复溶蛋白溶液可在4～7℃保存2～7天，可分装后置于-20℃保存三个月。

STAT1复溶：
打开试剂管前请先离心。
复溶浓度推荐大于100 μg/ml。
冻干蛋白请溶于ddH2O。
复溶后，请根据用量分装冻存，避免反复冻融。

关于STAT1：
Signal Transducer and Activator of Transcription 1-Alpha/Beta (STAT1) contains one SH2 domain and belongs to the transcription factor STAT family. When tyrosine- and serine-phosphorylated, STAT1 can form a homodimer termed IFN-gamma-activated factor (GAF), migrate into the nucleus and bind to the IFN gamma activated sequence (GAS) to drive the expression of the target genes, inducing a cellular antiviral state. STAT1 functions as signal transducer and transcription activator that mediates cellular responses to interferons. Defects in STAT1 are the cause of STAT1 deficiency complete and familial candidiasis type 7.


重组小鼠内皮细胞特异性分子1(Endo*(代"c")an)打折促销关键词：重组小鼠内皮细胞特异性分子1,重组小鼠Endo*(代"c")an,重组内皮细胞特异性分子1,JN1497,重组小鼠内皮细胞特异性分子1蛋白


·重组小鼠VEGFD(血管内皮生长因子D)(带His标签)
编号：JN0250
英文名称：Recombinant Mouse Vascular Endothelial Growth Factor D
规格：10μg|50μg|500μg|1mg
本品由我们的哺乳动物表达系统制备，目的基因编码的Phe98-Ser206在C端含有His标签。

VEGFD质量控制：＞95%(还原性SDS-PAGE)。

VEGFD制剂：冻干品

VEGFD保存：
冻干蛋白可在-20℃长期保存，室温也可稳定保存3周。
复溶蛋白溶液可在4～7℃保存2～7天。
复溶后建议分装冻存在-20℃，可保存3个月，应避免反复冻融。

VEGFD复溶：
1、试剂开盖前请先离心。
2、复溶浓度应大于100 μg/ml.
3、冻干蛋白溶于ddH2O中
4、复溶后根据使用量分装保存，避免反复冻融。

关于VEGFD：
Mouse vascular endothelial growth factor D, (VEGFD) is a member of the platelet-derived growth factor/vascular endothelial growth factor (PDGF/VEGF) family. VEGFD is a secreted protein and highly expressed in fetal and adult lung. It undergoes a complex proteolytic maturation, generating multiple processed forms that bind and activate VEGFR-2 and VEGFR-3 receptors. The structure and function of this protein is similar to VEGFC. VEGFD is growth factor which active in angiogenesis, lymphangiogenesis, and endothelial cell growth, stimulating their proliferation and migration and also has effects on the permeability of blood vessels.

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