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- 详细信息
- 文献和实验
- 技术资料
- 库存:
307
- 英文名:
Recombinant Human Low Affinity Immunoglobulin Gamma Fc Region Receptor III-A
- 保质期:
长期
- 供应商:
北京百奥莱博科技有限公司
- 保存条件:
冻干蛋白置于-20℃
特别声明:本产品及我公司所售其他产品均为科研类试剂产品,严禁用于药物、医疗及其他非科研用途。
北京百奥莱博专业生产销*(代"售")重组人Fc gamma RIIIA(CD16a)(FCGR3A)北京厂家,我公司供应的分子生物学试剂品类齐全,且具有优势价格,欢迎新老客户垂询订购。
名称:重组人Fc gamma RIIIA(CD16a)(FCGR3A)北京厂家
英文名:Recombinant Human Low Affinity Immunoglobulin Gamma Fc Region Receptor III-A
品牌:百奥莱博
产地:国产|进口
规格:10μg|50μg|500μg|1mg
编号:JN1829
本品由我们的哺乳动物细胞表达系统制备而成,目的基因编码的Gly17-Gln208在C端含有His标签。
Fc gamma RIIIA/CD16a/FCGR3A质量控制:>95%(还原性SDS-PAGE)
Fc gamma RIIIA/CD16a/FCGR3A制剂:冻干品
Fc gamma RIIIA/CD16a/FCGR3A保存:
冻干蛋白置于-20℃以下可长期保存,室温条件下可稳定保存3周。
复溶蛋白溶液可在4~7℃保存2~7天,可分装后置于-20℃保存三个月。
Fc gamma RIIIA/CD16a/FCGR3A复溶:
打开试剂管前请先离心。
复溶浓度推荐大于100 μg/ml。
冻干蛋白请溶于ddH2O。
复溶后,请根据用量分装冻存,避免反复冻融。
关于Fc gamma RIIIA/CD16a/FCGR3A:
Receptors for the Fc region of immunoglobin G (FcγR) are divided into three classes and FcγRIII is a multifunctional, low/intermediate affinity receptor. In humans, FcγRIII is expressed as two distinct forms (FcγRIIIA and FcγRIIIB) that are encoded by two different but highly homologous genes in a cell type-specific manner. FcγRIIIB is a low-affinity, GPI-linked receptor expressed by neutrophils and eosinophils, whereas FcγRIIIA is an intermediate affinity polypeptide-anchored transmembrane glycoprotein expressed by a subset of T lymphocytes, natural killer (NK) cells, monocytes, and macrophages. The FcγRIIIA receptor is involved in phagocytosis, secretion of enzymes, inflammatory mediators, antibody-dependent cellular cytotoxicity (ADCC), mast cell degranulation, and clearance of immune complexes. FcγRIIIA has an immunoreceptor tyrosine-based activation motif (ITAM) in its cytoplasmic domain and delivers an activation signal in the immune responses. Aberrant expression or mutations in this gene is implicated in susceptibility to recurrent viral infections, systemic lupus erythematosus, and alloimmune neonatal neutropenia. In humans, it is a 50 -70 kD type I transmembrane activating receptor. The FcγRIIIA cDNA encodes 254 amino acid including a 16aa signal sequence, 191 amino acid ECD with two C2-type Ig-like domains, five potential N-glycosylation sites, a 22 amino acid transmembrane sequence and a 25 amino acid cytoplasmic domain.
欲咨询购买重组人Fc gamma RIIIA(CD16a)(FCGR3A)北京厂家,请致电北京百奥莱博科技有限公司,为您提供最全面周到的产品服务,除此之外,我公司正在促销以下产品:
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重组人Fc gamma RIIIA(CD16a)(FCGR3A)北京厂家关键词:重组人FCGR3A,重组人Fc gamma RIIIA,重组人CD16a,JN1829,重组人Fc gamma RIIIA蛋白
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重组人Fc gamma RIIIA(CD16a)(FCGR3A)北京厂家关键词:重组人FCGR3A,重组人Fc gamma RIIIA,重组人CD16a,JN1829,重组人Fc gamma RIIIA蛋白
·重组人白介素IL-2(白细胞介素2)
编号:JN0335
英文名称:Recombinant Human Interleukin-2
规格:10μg|50μg|500μg|1mg
本品由我们的大肠杆菌表达系统制备,目的基因编码的Ala21-Thr153表达纯化而来。
IL-2质量控制:>95%(还原性SDS-PAGE)。
IL-2制剂:冻干品
IL-2保存:
冻干蛋白可在-20℃长期保存,室温也可稳定保存3周。
复溶蛋白溶液可在4~7℃保存2~7天。
复溶后建议分装冻存在-20℃,可保存3个月,应避免反复冻融。
IL-2复溶:
1、试剂开盖前请先离心。
2、复溶浓度应大于100 μg/ml.
3、冻干蛋白溶于ddH2O中
4、复溶后根据使用量分装保存,避免反复冻融。
关于IL-2:
Recombinant Human Interleukin-2 is a highly purified protein with a molecular weight of approximately 15,300 Daltons. The chemical name is des-alanyl-1, serine-125 Human Interleukin-2. It is produced by recombinant DNA technology using a genetically engineered E.coli strain containing an analog of the human interleukin-2 gene. Genetic engineering techniques were used to modify the Human IL-2 gene, and the resulting expression clone encodes a modified Human IL-2. This recombinant form differs from native Interleukin-2 in following ways: 1) it is not glycosylated; 2) the molecule has no N-terminal alanine; 3) the molecule has serine substituted for cysteine at amino acid position 125; 4) the aggregation state of molecule is likely to be different from that of native IL-2.
我公司正在打折促销重组蛋白全系列产品,恭候您的咨询选购重组人Fc gamma RIIIA(CD16a)(FCGR3A)北京厂家。
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文献和实验Age-Related Alterations to Natural Killer Cell Function
Human natural killer (NK) cells represent a heterogeneous lymphoid population involved in the recognition and lysis of tumor and virally infected cells. NK cells are defined by the expression of the IgG Fc receptor CD16 (FcγRIIIA) and/or CD
Multiple Color Immunofluorescence for Cytokine Detection at the Single Cell Level
Upon proper stimulation (e.g., crosslinking FcγRIIIA [CD16], interaction with antibody [Ab]-nonsensitized target cells, cytokines), mature natural killer (NK) cells produce and release cytokines involved in the modulation of immune responses
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