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Rat PDGF-AB ELISA Kit

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  • $455
  • innov-research
  • IRKTAH5529
  • 美国/英国
  • 2025年07月08日
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    • 详细信息
    • 文献和实验
    • 技术资料
    • 库存

      50

    • 英文名

      Rat PDGF-AB ELISA Kit

    • 保质期

      十二个月

    • 供应商

      信裕生物

    • 保存条件

      -20°C

    • 规格

      96 tests

    Rat PDGF-AB ELISA Kit

    Catalog No.: IRKTAH5529

    $455
    Category: Assay and ELISA Kits

    Product Description

    Rat PDGF-AB ELISA Kit - 1 Kit (96 Wells)

    Our Rat PDGF-AB ELISA Kit is a sandwich ELISA intended for the quantitative determination of rat PDGF-AB in cell culture supernates, serum and plasma (heparin, EDTA).

    The platelet-derived growth factor(PDGF) is a mitogen derived from human platelets consisting of two related polypeptides termed A and B chains. The genes for PDGF A chain, B chain/c-sis, and the PDGF receptor are expressed in human malignant glioma cell lines. Normal human endothelial cells in culture express the B chain of PDGF, and that endothelial-derived PDGF B chain is synthesized as a predicted precursor polypeptide of Mr 27,281. The entire B chain of PDGF is highly(96%) homologous to a portion of p28sis, the transforming protein of simian sarcoma virus(SSV). It has been suggested that p28sis exerts its transforming potential by mimicking the growth promoting activity of PDGF and stimulating the cell in an autocrine manner. PDGF A-chain precursor polypeptide is assigned to the proximal long arm of chromosome 7, band q11.23. The human homolog(PDGF B-chain/c-sis) of the transforming gene of simian sarcoma virus is assigned to chromosome 22. The standard product used in this kit is recombinant rat PDGF-AB(A chain Ser87-Arg196; B chain Ser74-Thr182) with the molecular mass of 24.8KDa.

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