孤儿核受体抗体品牌

公司抗体应用于WB、IHC、IF、ELISA等实验中，孤儿核受体抗体品牌品质保证，提供完善的售前、售中、售后服务！欢迎来电咨询或联系在线客服！我们将竭诚为您服务！
英文名称  Anti-ROR Gamma/RORC/NR1F3 
中文名称  孤儿核受体抗体品牌
别    名  NR1F3; Nuclear receptor ROR gamma; Nuclear receptor ROR-gamma; Nuclear receptor RZR gamma; Nuclear receptor RZR-gamma; Nuclear receptor subfamily 1 group F member 3; RAR related orphan receptor C; RAR related orphan receptor C, isoform a; RAR related orphan receptor gamma; Retinoic acid binding receptor gamma; Retinoid related orphan receptor gamma; Retinoid-related orphan receptor-gamma; Rorc; RORG; RZR GAMMA; RZRG; TOR. 
浓    度  1mg/1ml 
规 格  0.2ml/200μg
抗体来源  Rabbit  
克隆类型  polyclonal 
交叉反应  Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit  
产品类型  一抗    
研究领域  免疫学 信号转导 转录调节因子  
蛋白分子量  predicted molecular weight: 57kDa 
性    状  Lyophilized or Liquid 
免 疫 原  KLH conjugated synthetic peptide derived from human ROR Gamma (81-140aa) 
亚    型  IgG 
纯化方法  affinity purified by Protein A 
储 存 液  0.01M PBS, pH 7.4 with 10 mg/ml BSA and 0.1% Sodium azide 
产品应用   WB=1:100-500  ELISA=1:500-1000  IP=1:20-100  IHC-P=1:100-500  IHC-F=1:100-500  IF=1:100-500 
（石蜡切片需做抗原修复） 
 not yet tested in other applications.
 optimal dilutions/concentrations should be determined by the end user.  
保存条件  Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. 
Important Note  This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. 
产品介绍 The protein encoded by this gene is a DNA-binding transcription factor and is a member of the NR1 subfamily of nuclear hormone receptors. The specific functions of this protein are not known; however, studies of a similar gene in mice have shown that this gene may be essential for lymphoid organogenesis and may play an important regulatory role in thymopoiesis. In addition, studies in mice suggest that the protein encoded by this gene may inhibit the expression of Fas ligand and IL2. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]. 
Function : Possible nuclear receptor for hydroxycholesterols, the binding of which strongly promotes coactivators recruitment. Essential for thymopoiesis and the development of several secondary lymphoid tissues, including lymph nodes. Involved in lineage specification of uncommitted CD4(+) T helper cells into Th17 cells. Regulate the expression of several components of the circadian clock.
Subcellular Location : Nucleus (Probable).
Tissue Specificity : Isoform 1: widely expressed in many tissues, including liver and adipose, and highly expressed in skeletal muscle. Isoform 2: Primarily expressed in immature thymocytes.
Similarity : Belongs to the nuclear hormone receptor family. NR1 subfamily.
Contains 1 nuclear receptor DNA-binding domain.
Database links : UniProtKB/Swiss-Prot:
孤儿核受体抗体品牌具有高度的特异性，免疫组织化学正是利用了这一原理。先将组织或细胞中的某种化学物质提取出来，以此作为抗原或半抗原，通过免疫动物后获得特异性的抗体，再以此抗体去探测组织或细胞中的同类的抗原物质。由于抗原与抗体的复合物是无色的，因此还必须借助于组织化学的方法将抗原抗体结合的部位显示出来，以其达到对组织或细胞中的未知抗原进行定性，定位或定量的研究。
孤儿核受体抗体品牌包括以下几个步骤：
1、制备抗原。
2、选择实验动物。
3、动物免疫。
4、试取血进行测试，看看是否成功免疫。
5、如果成功免疫，杀死实验动物，采集全部血清。
6、纯化出抗体。
7、鉴定抗体。包括纯度以及特异性。
孤儿核受体抗体品牌的功能
抗体的主要功能是与抗原（包括外来的和自身的）相结合，从而有效地清除侵入机体内的微生物、寄生虫等异物，抗体（antibody）是一种应答抗原产生的、可与抗原特异性结合的蛋白质。每种抗体与特定的抗原决定基结合。这种结合可以使抗原失活，也可能无效但有时也会对机体造成病理性损害，如抗核抗体、抗双链DNA抗体、抗甲状腺球蛋白抗体等一些自身抗体的产生，对人体可造成危害。
孤儿核受体抗体品牌的优点：
①耐热、耐酸、耐碱、抗有机溶剂以及金属离子，稳定性好，室温下可以长期保存；
②制备简单，操作方便，可以进行批量；
③不必免疫动物，且可获得免疫动物所不能得到的“抗体”；
④可以反复使用；
⑤价格低廉。因此，设计、合成既具有类似生物抗体的高亲合性和高专一性，又具有耐热、耐酸、耐碱且又可以长期稳定的人工抗体，在部分领域替代生物抗体以进行仿生分子识别，或者完成一些生物抗体所不能完成的工作，具有重要的科学意义，在化学、生命科学和环境科学等方面具有广阔的应用前景
公司专业供应各种进口、国产一抗及二抗，品牌有R&D、Santa Cruz、Bipec、Millipore等国际知名品牌，品种多达7000多种，由于产品的数量众多，产品的宿主、抗原来源及应用范围(WB、IH(F/P)、FC、ELISA、IP、IF等)有所不同。
Tubb3/Tubulinbeta3微管蛋白β3抗体规格:0.1ml
BTBD1BTB/POZ结构域蛋白1（丙型肝炎病毒的NS5A反转录蛋白8）抗体规格:0.2ml
RabbitAnti-Avidin/PE-Cy5.5PE-Cy5.5标记的兔抗亲和素规格:0.1ml
DP-I桥粒斑蛋白1抗体规格:0.2ml
AP2alpha转录激活蛋白2α抗体规格:0.1ml
PDHA1/PDH-E1α丙酮酸脱酶α1抗体规格:0.2ml
phospho-MYF5(phosphoSer49)磷酸化生肌决定因子Myf5抗体规格:0.1ml
T3三碘甲狀素T3抗体规格:0.1ml
phospho-CAMK2G(Ter286)磷酸化钙/钙调素依赖蛋白激酶CAMK2G抗体规格:0.1ml
ESRRG/EstrogenRelatedReceptorgamma雌激素受体相关蛋白3抗体规格:0.2ml
[Lys0]-γ-1-MSH (41-58), amide    Lys-Tyr-Val-Met-Gly-His-Phe-Arg-Trp-Asp-Arg-Phe-Gly-NH2
[Pyr4]-MBP (4-14)    Pyr-Lys-Arg-Pro-Ser-Gln-Arg-Ser-Lys-Tyr-Leu
[Tyr27]-a-CGRP (27-37) (canine, mouse, rat)    Tyr-Val-Pro-Thr-Asn-Val-Gly-Ser-Glu-Ala-Phe-NH2
Ac-[Asn30,Tyr32]-Calcitonin (8-32) (salmon I)    Ac-Val-Leu-Gly-Lys-Leu-Ser-Gln-Glu-Leu-His-Lys-Leu-Gln-Thr-Tyr-Pro-Arg-Thr-Asn-Thr-Gly-Ser-Asn-Thr-Tyr-NH2
孤儿核受体抗体品牌ACTH (4-10), human    Met-Glu-His-Phe-Arg-Trp-Gly
Alloferon 1    His-Gly-Val-Ser-Gly-His-Gly-Gln-His-Gly-Val-His-Gly
ANP (1-30), frog    Ala-Pro-Arg-Ser-Met-Arg-Arg-Ser-Ser-Asp-Cys-Phe-Gly-Ser-Arg-Ile-Asp-Arg-Ile-Gly-Ala-Gln-Ser-Gly-Met-Gly-Cys-Gly-Arg-Phe（Disulfide bridge:Cys11-Cys27）
Bid BH3-r8    D-Arg-D-Arg-D-Arg-D-Arg-D-Arg-D-Arg-D-Arg-D-Arg-Gly-Glu-Asp-Ile-Ile-Arg-Asn-Ile-Ala-Arg- His-Leu-Ala-Gln-Val-Gly-Asp-Ser-Met-Asp-Arg
Biotin-Tyrosine Kinase Peptide 1, amide    Biotin-Lys-Val-Glu-Lys-Ile-Gly-Glu-Gly-Thr-Tyr-Gly-Val-Val-Tyr-Lys-NH2
C3a (70-77)    Ala-Ser-His-Leu-Gly-Leu-Ala-Arg
CEA, CAP-1-6-D, [Asp6]-Carcinoembryonic Antigen    Tyr-Leu-Ser-Gly-Ala-Asp-Leu-Asn-Leu
CREBtide    Gly-Glu-Ile-Leu-Ser-Arg-Arg-Pro-Ser-Tyr-Arg-Lys-NH2
Dynorphin A (1-13), porcine    Tyr-Gly-Gly-Phe-Leu-Arg-Arg-Ile-Arg-Pro-Lys-Leu-Lys