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- 详细信息
- 技术资料
- 抗体名:
RAB3-GTP酶激活蛋白催化亚单位2抗体
- 抗体英文名:
Anti-RAB3GAP2
- 靶点:
详见说明书
- 浓度:
1mg/1ml
- 应用范围:
WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500
- 宿主:
详见说明书
- 供应商:
上海一研
- 库存:
29
- 级别:
详见说明书
- 目录编号:
详见说明书
- 抗原来源:
Rabbit
- 保质期:
详见说明书
- 适应物种:
详见说明书
- 标记物:
详见说明书
- 克隆性:
多克隆
- 保存条件:
Store at -20 °C
- 形态:
详见说明书
- 亚型:
IgG
- 免疫原:
KLH conjugated synthetic peptide derived from human RAB3GAP2
- 规格:
0.2ml/200μg
公司抗体应用于WB、IHC、IF、ELISA等实验中,RAB3-GTP酶激活蛋白催化亚单位1抗体说明书品质保证,提供完善的售前、售中、售后服务!欢迎来电咨询或联系在线客服!我们将竭诚为您服务!
英文名称 Anti-RAB3GAP2
中文名称 RAB3-GTP酶激活蛋白催化亚单位1抗体说明书
别 名 DKFZp434D245; FLJ14579; KIAA0839; p150; Rab3 GAP p150; Rab3 GAP regulatory subunit; Rab3 GAP150; Rab3 GTPase activating protein 150 kDa subunit; Rab3 GTPase activating protein non catalytic subunit; RAB3 GTPase activating protein subunit 2 (non catalytic); RAB3 GTPase activating protein subunit 2; RAB3GAP150; RGAP iso; RP11 568G11.1; RBGPR_HUMAN.
浓 度 1mg/1ml
规 格 0.2ml/200μg
抗体来源 Rabbit
克隆类型 polyclonal
交叉反应 Human, Mouse, Rat, Dog, Cow, Horse, Rabbit, Sheep
产品类型 一抗
研究领域 细胞生物 发育生物学 神经生物学 信号转导 G蛋白信号
蛋白分子量 predicted molecular weight: 156kDa
性 状 Lyophilized or Liquid
免 疫 原 KLH conjugated synthetic peptide derived from human RAB3GAP2
亚 型 IgG
纯化方法 affinity purified by Protein A
储 存 液 Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4
产品应用 WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500
(石蜡切片需做抗原修复)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Important Note This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
产品介绍 ab 3 GAP p150 is a ubiquitously expressed protein that contains 1,393 amino acids and belongs to the Rab3-GAP regulatory subunit family. Defects in Rab 3 GAP p150 are the cause of Martsolf and Warburg Micro syndrome. Both syndromes are characterized by congenital cataracts, microphthalmia, postnatal microcephaly and developmental delay, and are inherited in an autosomal recessive manner. The Rab3 GTPase-activating complex is a heterodimer composed of RAB3GAP and Rab 3 GAP p150 that interacts with DMXL2. Existing as two alternatively spliced isoforms, the Rab 3 GAP p150 gene is conserved in chimpanzee, dog, cow, rat, chicken, zebrafish, fruit fly, mosquito, A.thaliana and rice. The Rab 3 GAP p150 gene contains 36 exons and maps to human chromosome 1q41.
Function : RAB3GAP2 is a regulatory subunit of a GTPase activating protein that has specificity for Rab3 subfamily (RAB3A, RAB3B, RAB3C and RAB3D). Rab3 proteins are involved in regulated exocytosis of neurotransmitters and hormones. Rab3 GTPase-activating complex specifically converts active Rab3-GTP to the inactive form Rab3-GDP. It is required for normal eye and brain development and may participate in neurodevelopmental processes such as proliferation, migration and differentiation before synapse formation, and non-synaptic vesicular release of neurotransmitters.
Subunit : The Rab3 GTPase-activating complex is a heterodimer composed of RAB3GAP and RAB3-GAP150. The Rab3 GTPase-activating complex interacts with DMXL2
Subcellular Location : Cytoplasm. Note=In neurons, it is enriched in the synaptic soluble fraction.
Tissue Specificity : Ubiquitous.
DISEASE : efects in RAB3GAP2 are the cause of Martsolf syndrome (MARTS) [MIM:212720]. Martsolf syndrome is characterized by congenital cataracts, mental retardation, and hypogonadism. Inheritance is autosomal recessive.
Defects in RAB3GAP2 are the cause of Warburg micro syndrome type 2 (WARBM2) [MIM:614225]. WARBM2 is a rare syndrome characterized by microcephaly, microphthalmia, microcornia, congenital cataracts, optic atrophy, cortical dysplasia, in particular corpus callosum hypoplasia, severe mental retardation, spastic diplegia, and hypogonadism.
Similarity : Belongs to the Rab3-GAP regulatory subunit family.
Database links : UniProtKB/Swiss-Prot: Q9H2M9.1
RAB3-GTP酶激活蛋白催化亚单位1抗体说明书具有高度的特异性,免疫组织化学正是利用了这一原理。先将组织或细胞中的某种化学物质提取出来,以此作为抗原或半抗原,通过免疫动物后获得特异性的抗体,再以此抗体去探测组织或细胞中的同类的抗原物质。由于抗原与抗体的复合物是无色的,因此还必须借助于组织化学的方法将抗原抗体结合的部位显示出来,以其达到对组织或细胞中的未知抗原进行定性,定位或定量的研究。
RAB3-GTP酶激活蛋白催化亚单位1抗体说明书包括以下几个步骤:
1、制备抗原。
2、选择实验动物。
3、动物免疫。
4、试取血进行测试,看看是否成功免疫。
5、如果成功免疫,杀死实验动物,采集全部血清。
6、纯化出抗体。
7、鉴定抗体。包括纯度以及特异性。
RAB3-GTP酶激活蛋白催化亚单位1抗体说明书的功能
抗体的主要功能是与抗原(包括外来的和自身的)相结合,从而有效地清除侵入机体内的微生物、寄生虫等异物,抗体(antibody)是一种应答抗原产生的、可与抗原特异性结合的蛋白质。每种抗体与特定的抗原决定基结合。这种结合可以使抗原失活,也可能无效但有时也会对机体造成病理性损害,如抗核抗体、抗双链DNA抗体、抗甲状腺球蛋白抗体等一些自身抗体的产生,对人体可造成危害。
RAB3-GTP酶激活蛋白催化亚单位1抗体说明书的优点:
①耐热、耐酸、耐碱、抗有机溶剂以及金属离子,稳定性好,室温下可以长期保存;
②制备简单,操作方便,可以进行批量;
③不必免疫动物,且可获得免疫动物所不能得到的“抗体”;
④可以反复使用;
⑤价格低廉。因此,设计、合成既具有类似生物抗体的高亲合性和高专一性,又具有耐热、耐酸、耐碱且又可以长期稳定的人工抗体,在部分领域替代生物抗体以进行仿生分子识别,或者完成一些生物抗体所不能完成的工作,具有重要的科学意义,在化学、生命科学和环境科学等方面具有广阔的应用前景
公司专业供应各种进口、国产一抗及二抗,品牌有R&D、Santa Cruz、Bipec、Millipore等国际知名品牌,品种多达7000多种,由于产品的数量众多,产品的宿主、抗原来源及应用范围(WB、IH(F/P)、FC、ELISA、IP、IF等)有所不同。
KCNG2心脏钾离子通道蛋白亚基2抗体 规格: 0.2ml GLP-1(7-36)胰高糖素样肽-1抗体 规格: 0.1ml
Staufen/STAU1双链RNA结合蛋白Staufen抗体 规格: 0.2ml β-Amyloid(1-42)β淀粉样肽(1-42)抗体 规格: 0.1ml
C4orf144号染色体开放阅读框14抗体 规格: 0.2ml glypican3/GPC3磷脂酰基醇蛋白聚糖-3抗体 规格: 0.1ml
Rad17/RFC细胞周期检控Rad17蛋白抗体(复制因子C) 规格: 0.1ml Tankyrase端粒调控因子抗体 规格: 0.2ml
TGFbeta2Propeptide转移生因子β2抗体 规格: 0.1ml GoatAnti-BovineIgG/APCAPC标记的羊抗牛IgG 规格: 0.1ml
ThymosinAlpha-1/PTMA胸肽α1抗体 规格: 0.1ml Cripto1monoclonal(CT)畸胎瘤衍化生因子单克隆抗体(C端) 规格: 0.1ml
TSHR促甲状素受体抗体 规格: 0.1ml MAGEA10黑色素瘤相关抗原10抗体 规格: 0.2ml
Phospho-Tuberin/TSC2(Ser939)磷酸化马铃薯球蛋白(结节性硬化)抗体 规格: 0.1ml Eukaryoticaspartylprotease天冬氨酸蛋白酶家族蛋白抗体 规格: 1ml
REEP5受体表达蛋白5/息肉相关蛋白抗体 规格: 0.2ml SKA3纺锤体和着丝粒相关蛋白3抗体 规格: 0.2ml
FactorIX凝因子9抗体 规格: 0.2ml RCC1染色体浓调控蛋白1抗体 规格: 0.2ml
NTF97/KPNB1亲核素β1抗体 规格: 0.1ml ATM毛细管扩张性共济失调症突变蛋白抗体 规格: 0.1ml
C20orf19520号染色体开放阅读框195抗体 规格: 0.2ml ATG16L2自噬体ATG16L2蛋白抗体 规格: 0.2ml
RabbitAnti-mouseIgG-Fc/Cy5Cy5标记的兔抗小鼠IgG-Fc 规格: 0.1ml Rabbitanti-GoatIgMwholeserum兔抗羊IgM抗清 规格: 1ml兔抗猴IgG(免疫血清) 5ml 支
RAB3-GTP酶激活蛋白催化亚单位1抗体说明书荧光抗体稀释液 10ml 瓶
1.5ml 样品瓶,蓝盖,开孔,带刻度棕色 100支 盒
ANNEXIN V-FITC-PI 凋亡检测试剂盒 100T 盒
Stigmasterol 豆甾醇 83-48-7 20mg
Magnolol 厚朴酚 528-43-8 20mg
Epimedin A 朝藿定A 110623-72-8 20mg
Benzoylmesaconine 苯甲酰新原碱 63238-67-5 20mg
L-(+)-Lactic acid L-乳酸 79-33-4 20mg
Gliclazide 格列齐特 21187-98-4 20mg
圆盖玻片 直径16mm 100片 盒
玻璃纸 100×120cm 10张/包
4-Dimethylaminopyridine 4-二甲氨基吡啶 5g 瓶
英文名称 Anti-RAB3GAP2
中文名称 RAB3-GTP酶激活蛋白催化亚单位1抗体说明书
别 名 DKFZp434D245; FLJ14579; KIAA0839; p150; Rab3 GAP p150; Rab3 GAP regulatory subunit; Rab3 GAP150; Rab3 GTPase activating protein 150 kDa subunit; Rab3 GTPase activating protein non catalytic subunit; RAB3 GTPase activating protein subunit 2 (non catalytic); RAB3 GTPase activating protein subunit 2; RAB3GAP150; RGAP iso; RP11 568G11.1; RBGPR_HUMAN.
浓 度 1mg/1ml
规 格 0.2ml/200μg
抗体来源 Rabbit
克隆类型 polyclonal
交叉反应 Human, Mouse, Rat, Dog, Cow, Horse, Rabbit, Sheep
产品类型 一抗
研究领域 细胞生物 发育生物学 神经生物学 信号转导 G蛋白信号
蛋白分子量 predicted molecular weight: 156kDa
性 状 Lyophilized or Liquid
免 疫 原 KLH conjugated synthetic peptide derived from human RAB3GAP2
亚 型 IgG
纯化方法 affinity purified by Protein A
储 存 液 Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4
产品应用 WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500
(石蜡切片需做抗原修复)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Important Note This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
产品介绍 ab 3 GAP p150 is a ubiquitously expressed protein that contains 1,393 amino acids and belongs to the Rab3-GAP regulatory subunit family. Defects in Rab 3 GAP p150 are the cause of Martsolf and Warburg Micro syndrome. Both syndromes are characterized by congenital cataracts, microphthalmia, postnatal microcephaly and developmental delay, and are inherited in an autosomal recessive manner. The Rab3 GTPase-activating complex is a heterodimer composed of RAB3GAP and Rab 3 GAP p150 that interacts with DMXL2. Existing as two alternatively spliced isoforms, the Rab 3 GAP p150 gene is conserved in chimpanzee, dog, cow, rat, chicken, zebrafish, fruit fly, mosquito, A.thaliana and rice. The Rab 3 GAP p150 gene contains 36 exons and maps to human chromosome 1q41.
Function : RAB3GAP2 is a regulatory subunit of a GTPase activating protein that has specificity for Rab3 subfamily (RAB3A, RAB3B, RAB3C and RAB3D). Rab3 proteins are involved in regulated exocytosis of neurotransmitters and hormones. Rab3 GTPase-activating complex specifically converts active Rab3-GTP to the inactive form Rab3-GDP. It is required for normal eye and brain development and may participate in neurodevelopmental processes such as proliferation, migration and differentiation before synapse formation, and non-synaptic vesicular release of neurotransmitters.
Subunit : The Rab3 GTPase-activating complex is a heterodimer composed of RAB3GAP and RAB3-GAP150. The Rab3 GTPase-activating complex interacts with DMXL2
Subcellular Location : Cytoplasm. Note=In neurons, it is enriched in the synaptic soluble fraction.
Tissue Specificity : Ubiquitous.
DISEASE : efects in RAB3GAP2 are the cause of Martsolf syndrome (MARTS) [MIM:212720]. Martsolf syndrome is characterized by congenital cataracts, mental retardation, and hypogonadism. Inheritance is autosomal recessive.
Defects in RAB3GAP2 are the cause of Warburg micro syndrome type 2 (WARBM2) [MIM:614225]. WARBM2 is a rare syndrome characterized by microcephaly, microphthalmia, microcornia, congenital cataracts, optic atrophy, cortical dysplasia, in particular corpus callosum hypoplasia, severe mental retardation, spastic diplegia, and hypogonadism.
Similarity : Belongs to the Rab3-GAP regulatory subunit family.
Database links : UniProtKB/Swiss-Prot: Q9H2M9.1
RAB3-GTP酶激活蛋白催化亚单位1抗体说明书具有高度的特异性,免疫组织化学正是利用了这一原理。先将组织或细胞中的某种化学物质提取出来,以此作为抗原或半抗原,通过免疫动物后获得特异性的抗体,再以此抗体去探测组织或细胞中的同类的抗原物质。由于抗原与抗体的复合物是无色的,因此还必须借助于组织化学的方法将抗原抗体结合的部位显示出来,以其达到对组织或细胞中的未知抗原进行定性,定位或定量的研究。
RAB3-GTP酶激活蛋白催化亚单位1抗体说明书包括以下几个步骤:
1、制备抗原。
2、选择实验动物。
3、动物免疫。
4、试取血进行测试,看看是否成功免疫。
5、如果成功免疫,杀死实验动物,采集全部血清。
6、纯化出抗体。
7、鉴定抗体。包括纯度以及特异性。
RAB3-GTP酶激活蛋白催化亚单位1抗体说明书的功能
抗体的主要功能是与抗原(包括外来的和自身的)相结合,从而有效地清除侵入机体内的微生物、寄生虫等异物,抗体(antibody)是一种应答抗原产生的、可与抗原特异性结合的蛋白质。每种抗体与特定的抗原决定基结合。这种结合可以使抗原失活,也可能无效但有时也会对机体造成病理性损害,如抗核抗体、抗双链DNA抗体、抗甲状腺球蛋白抗体等一些自身抗体的产生,对人体可造成危害。
RAB3-GTP酶激活蛋白催化亚单位1抗体说明书的优点:
①耐热、耐酸、耐碱、抗有机溶剂以及金属离子,稳定性好,室温下可以长期保存;
②制备简单,操作方便,可以进行批量;
③不必免疫动物,且可获得免疫动物所不能得到的“抗体”;
④可以反复使用;
⑤价格低廉。因此,设计、合成既具有类似生物抗体的高亲合性和高专一性,又具有耐热、耐酸、耐碱且又可以长期稳定的人工抗体,在部分领域替代生物抗体以进行仿生分子识别,或者完成一些生物抗体所不能完成的工作,具有重要的科学意义,在化学、生命科学和环境科学等方面具有广阔的应用前景
公司专业供应各种进口、国产一抗及二抗,品牌有R&D、Santa Cruz、Bipec、Millipore等国际知名品牌,品种多达7000多种,由于产品的数量众多,产品的宿主、抗原来源及应用范围(WB、IH(F/P)、FC、ELISA、IP、IF等)有所不同。
KCNG2心脏钾离子通道蛋白亚基2抗体 规格: 0.2ml GLP-1(7-36)胰高糖素样肽-1抗体 规格: 0.1ml
Staufen/STAU1双链RNA结合蛋白Staufen抗体 规格: 0.2ml β-Amyloid(1-42)β淀粉样肽(1-42)抗体 规格: 0.1ml
C4orf144号染色体开放阅读框14抗体 规格: 0.2ml glypican3/GPC3磷脂酰基醇蛋白聚糖-3抗体 规格: 0.1ml
Rad17/RFC细胞周期检控Rad17蛋白抗体(复制因子C) 规格: 0.1ml Tankyrase端粒调控因子抗体 规格: 0.2ml
TGFbeta2Propeptide转移生因子β2抗体 规格: 0.1ml GoatAnti-BovineIgG/APCAPC标记的羊抗牛IgG 规格: 0.1ml
ThymosinAlpha-1/PTMA胸肽α1抗体 规格: 0.1ml Cripto1monoclonal(CT)畸胎瘤衍化生因子单克隆抗体(C端) 规格: 0.1ml
TSHR促甲状素受体抗体 规格: 0.1ml MAGEA10黑色素瘤相关抗原10抗体 规格: 0.2ml
Phospho-Tuberin/TSC2(Ser939)磷酸化马铃薯球蛋白(结节性硬化)抗体 规格: 0.1ml Eukaryoticaspartylprotease天冬氨酸蛋白酶家族蛋白抗体 规格: 1ml
REEP5受体表达蛋白5/息肉相关蛋白抗体 规格: 0.2ml SKA3纺锤体和着丝粒相关蛋白3抗体 规格: 0.2ml
FactorIX凝因子9抗体 规格: 0.2ml RCC1染色体浓调控蛋白1抗体 规格: 0.2ml
NTF97/KPNB1亲核素β1抗体 规格: 0.1ml ATM毛细管扩张性共济失调症突变蛋白抗体 规格: 0.1ml
C20orf19520号染色体开放阅读框195抗体 规格: 0.2ml ATG16L2自噬体ATG16L2蛋白抗体 规格: 0.2ml
RabbitAnti-mouseIgG-Fc/Cy5Cy5标记的兔抗小鼠IgG-Fc 规格: 0.1ml Rabbitanti-GoatIgMwholeserum兔抗羊IgM抗清 规格: 1ml兔抗猴IgG(免疫血清) 5ml 支
RAB3-GTP酶激活蛋白催化亚单位1抗体说明书荧光抗体稀释液 10ml 瓶
1.5ml 样品瓶,蓝盖,开孔,带刻度棕色 100支 盒
ANNEXIN V-FITC-PI 凋亡检测试剂盒 100T 盒
Stigmasterol 豆甾醇 83-48-7 20mg
Magnolol 厚朴酚 528-43-8 20mg
Epimedin A 朝藿定A 110623-72-8 20mg
Benzoylmesaconine 苯甲酰新原碱 63238-67-5 20mg
L-(+)-Lactic acid L-乳酸 79-33-4 20mg
Gliclazide 格列齐特 21187-98-4 20mg
圆盖玻片 直径16mm 100片 盒
玻璃纸 100×120cm 10张/包
4-Dimethylaminopyridine 4-二甲氨基吡啶 5g 瓶
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RAB3-GTP酶激活蛋白催化亚单位2抗体价格
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