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- 详细信息
- 文献和实验
- 技术资料
- 库存:
大量
- 英文名:
B7-1 (CD80), Rat Anti-Mouse
- 保质期:
1年
- 供应商:
上海沪震实业有限公司
- 保存条件:
-20°C
- 规格:
500µg/1mg
CATALOGUE NUMBER
ANT-133
SYNONYMS
LAB7, CD28LG, CD28LG1, CD28LG1, B71.TYPE
Rat Anti Mouse Monoclonal.INTRODUCTION
The B-lymphocyte activation antigen B7-1 provides regulatory signals for T lymphocytes as a consequence of binding to the CD28 and CTLA4 ligands of T cells CD-80 is involved in the costimulatory signal essential for t- lymphocyte activation. t-cell proliferation and cytokine production is induced by the binding of cd28 or ctla-4 to this receptor.CLONE
mB7-1.IMMUNOGEN
Purified mouse LPS-activated B cells.IG SUBCLASS
Rat IgG2a.PURIFICATION METHOD
Ion exchange column.FORMULATION
1mg/ml in PBS (after reconstitution).STORAGE PROCEDURES
Lyophilized: store at 4oC. After reconstitution, if not intended for use within a month, aliquot and store at -20oC.SOLUBILITY
Reconstitute with of H20. Mix gently, wash the sides of the vial and wait 30-60 seconds before use.APPLICATIONS
Blocking and staining antibody. For staining, use 10µl/1,000,000 cells. Titer for blocking T cell activation should be determined by the investigator.AVAILABLE CONJUGATES
This antibody is only available as purified antibody.USAGE
Prospec's products are furnished for LABORATORY ESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.风险提示:丁香通仅作为第三方平台,为商家信息发布提供平台空间。用户咨询产品时请注意保护个人信息及财产安全,合理判断,谨慎选购商品,商家和用户对交易行为负责。对于医疗器械类产品,请先查证核实企业经营资质和医疗器械产品注册证情况。
文献和实验CD80 分子 CD80 常用单克隆抗体或代号: B7- 1,BB1 主要表达细胞: Ba,Mac,TStr [B] 分子质量(kDa)和结构: gp60(IgSF) 功 能: 活化B细胞抗原,CD28、CTLA- 4配体,提供T细胞共刺激信号 CD80 Aka B7-1, BB1 Ligand for T cell marker CD28 or CTLA4 (CD152
Generation of Antibody Molecules Through Antibody Engineering
been overcome to a large extent using genetic-engineering techniques to produce chimeric mouse/human and completely human antibodies. Such an approach is particularly suitable because of the domain structure of the antibody molecule ( 2 ), where functional
Non-Replicating Recombinant Vaccinia Virus Expressing CD80 to Enhance T-Cell Stimulation
The following method describes the generation of a recombinant vaccinia virus expressing a costimulatory molecule (human CD80 or B7.1). The procedure first requires the cloning, by classical methods not described here, of the gene
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