- $495
- innov-research
- IRKTAH5208
- 美国/英国
- 2025年07月16日
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- 详细信息
- 技术资料
- 库存：
50
- 英文名：
Human PCSK9 ELISA Kit
- 保质期：
十二个月
- 供应商：
信裕生物
- 保存条件：
-20°C
- 规格：
96 tests
Human PCSK9 ELISA Kit
Catalog No.: IRKTAH5208
$495
Category: Assay and ELISA Kits
Product Description
Human PCSK9 ELISA Kit - 1 Kit (96 Wells)
Our Human PCSK9 ELISA Kit is a sandwich ELISA intended for the quantitative determination of human PCSK9 in cell culture supernates, serum and plasma (heparin, EDTA).Proprotein convertase subtilisin/kexin type 9, also known as PCSK9, is an enzyme that in humans is encoded by the PCSK9 gene. This gene encodes a proprotein convertase belonging to the proteinase K subfamily of the secretory subtilase family. By genomic sequence analysis, the PCSK9 gene was mapped to chromosome 1p32. This protein plays a major regulatory role in cholesterol homeostasis. PCSK9 binds to the epidermal growth factor-like repeat A(EGF-A) domain of the low-density lipoprotein receptor(LDLR), inducing LDLR degradation. Reduced LDLR levels result in decreased metabolism of low-density lipoproteins(LDL), which could lead to hypercholesterolemia. PCSK9 may also have a role in the differentiation of cortical neurons.
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