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Human MICA ELISA Kit

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  • $525
  • innov-research
  • IRKTAH5181
  • 美国/英国
  • 2025年07月16日
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    • 详细信息
    • 文献和实验
    • 技术资料
    • 库存

      50

    • 英文名

      Human MICA ELISA Kit

    • 保质期

      十二个月

    • 供应商

      信裕生物

    • 保存条件

      -20°C

    • 规格

      96 tests

    Human MICA ELISA Kit

    Catalog No.: IRKTAH5181

    $525
    Category: Assay and ELISA Kits

    Product Description

    Human MICA ELISA Kit - 1 Kit (96 Wells)

    Our Human MICA ELISA Kit is a sandwich ELISA intended for the quantitative determination of human MICA in cell culture supernates, cell lysates, tissue homogenates and serum.

    MHC class I polypeptide-related sequence A is a protein that in humans is encoded by the MICA gene.1 The MICA gene encodes a 383-amino acid polypeptide with a predicted mass of 43 kD.The MICA and MICB genes occur in a 200-kb region spanning the TNFA and TNFB cluster at 6p21.3.2 MICA and the closely related MICB were recognized by intestinal epithelial T cells expressing diverse V-delta-1 gamma/delta TCRs.3 The MICA protein product is expressed on the cell surface, although unlike canonical class I molecules does not seem to associate with beta-2-microglobulin. It is further distinguished by its unusual exon-intron organization and preferential expression in fibroblasts and epithelial cells. It is thought that MICA functions as a stress-induced antigen that is broadly recognized by NK cells, NKT cells, and most of the subtypes of T cells. MICA and other members of this family may have been selected for specialized functions that are either ancient or derived from those of typical MHC class I genes, in analogy to some of the nonclassic mouse H-2 genes. The standard product used in this kit is recombinant MICA, which is composed of 286 amino acids with the molecular mass of 59KDa.

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