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北京百奥莱博科技有限公司
431
p44/42 MAPK
单克隆
YT821
多克隆
人
二年
anti-Phospho-p44/42 MAPK antibody
磷酸化p44/42 MAPK单克隆抗体
小鼠
人,大鼠,小鼠,仓鼠,斑马鱼
含有磷酸化Thr202/Tyr204的一段人MAPK多肽
IgG1
液体
WB,IP,IF,FCM
1mg/ml
-20℃冻存,避光
特别声明:本产品及我公司所售其他产品均为科研类试剂产品,严禁用于药物、医疗及其他非科研用途。
北京百奥莱博专业生产供应磷酸化p44/42 MAPK抗体销*(代"售"),我公司销*(代"售")全品类的抗体抗原,价格优惠,欢迎广大科研工作者垂询订购。
名称:磷酸化p44/42 MAPK抗体销*(代"售")
品牌:百奥莱博
规格:>20次
编号:YT821
产地:国产|进口
英文名:anti-Phospho-p44/42 MAPK antibody
本抗体是用经过适当修饰的含有磷酸化Thr202/Tyr204的一段human MAPK多肽为抗原制备而成的抗Phospho-p44/42 MAPK(Thr202/Tyr204)小鼠单克隆抗体。本抗体如果用于常规的Western检测,至少可以检测20次。
本Phospho-p44/42 MAPK抗体不识别磷酸化或非磷酸化的SAPK/JNK,也不识别磷酸化或非磷酸化的p38 MAP kinase。
本抗体识别Thr202和Tyr204同时被磷酸化的p44/42 MAPK,常用于检测p44/42 MAPK的激活。
p44和p42 MAP kinase(即erk1和erk2)在调节细胞的生长、分化等过程中起重要作用。p44和p42 MAP kinase可以被生长因子、神经营养因子、细胞因子、激素、神经递质等多种细胞外信号激活。p44和p42 MAP kinase的激活依赖于MAP kinase
kinase(MEK)对Thr202和Tyr204的磷酸化。上述*基酸残基的位置为相对应于human MAP kinase的*基酸位置。
产品组份:
Phospho-p44/42 MAPK抗体————20μl
Western一抗稀释液————20ml
抗体参数:
免疫原物种:人
免疫原:含有磷酸化Thr202/Tyr204的一段人MAPK多肽
克隆性:单克隆
宿主:小鼠
用途:WB,IP,IF,FCM
交叉反应性:人,大鼠,小鼠,仓鼠,斑马鱼
同种型:IgG1
p44/42 MAPK分子量:44/42kD
推荐稀释比例:WB(1:1000),IP(1:250),IF(1:100),FCM(1:500)
注意事项:
1. 在Western实验后,请注意回收稀释的抗体。回收的抗体在进行Western实验时至少可以重复使用10次。稀释后的抗体,包括已经使用过的稀释抗体,4℃保存。
2. 回收后重复使用的抗体,使用方法同新鲜稀释的抗体。如果在重复使用过程中发现抗体出现轻微混浊现象,可以10000g离心1-3分钟,取上清用于后续检测。如果回收的抗体出现明显的絮状物或长霉长菌等情况,则可以考虑废弃该抗体。
3. 对于本抗体,Western检测时一抗要4℃缓慢摇动过夜,如果仅短时间与一抗孵育检测效果较差。
储存条件:-20℃,有效期一年。
想要了解更多关于磷酸化p44/42 MAPK抗体销*(代"售")的价格、品牌、厂家、说明书、促销信息,请和我们联*(代"系")。此外我公司还销*(代"售")下面的产品:
·兔抗LDHA抗体
编号:YT736
英文名称:LDHA Rabbit Polyclonal Antibody
规格:50μl
本品为来源于兔的抗LDHA的多克隆抗体。
宿主:兔
克隆性:多克隆抗体
用途:WB,IHC,FC
交叉反应性:人,小鼠,大鼠
分子量:37KDa
推荐稀释比例:WB(1:500-1:1000),IHC(1:200),FC(1:100-1:200)
About this Antibody | |
Name | LDHA Rabbit Polyclonal Antibody |
Category | Polyclonal antibody(pAb); Primary antibody |
Isotype | IgG |
Purification | Peptide affinity purified |
About the Immunogen | |
Immunogen | This antibody is produced by immunizing rabbits with a synthetic peptide (KLH-coupled) corresponding to a region of LDHA. |
Gene ID | 3939 |
SwissProt | YT0428 |
Synonyms | LDHA; LDH-M; LDH1; PIG19 |
Category | Metabolism |
Background | Lactate dehydrogenase (LDH) is an enzyme present in a wide variety of organisms, including plants and animals. It catalyses the interconversion of pyruvate and lactate with concomitant interconversion of NADH and NAD+. In medicine, LDH is often used as a marker of tissue breakdown as LDH is abundant in red blood cells and can function as a marker for hemolysis. In mammals, three types of LDH subunits (35 kDa) are encoded by the genes Ldh-A, Ldh-B, and Ldh-C. Lactate dehydrogenase B (LDH-B, heart subunit, LDH-H) is involved in the conversion of L-lactate and NAD to pryruvate and NADH and it is predominantly localized in the heart tissue. Similar to other LDH subunit, LDH-B is considered to be an important marker for germ cell tumor. |
About this Antibody | |
Name | cMet Rabbit Polyclonal Antibody |
Category | Polyclonal antibody(pAb); Primary antibody |
Isotype | IgG |
Purification | Peptide affinity purified |
About the Immunogen | |
Immunogen | This antibody is produced by immunizing rabbits with a synthetic peptide (KLH-coupled) corresponding to a region of cMet. |
Gene ID | 4233 |
SwissProt | P08581 |
Synonyms | EC 2.7.10.1; HGF receptor; HGF-SF receptor; Hepatocyte growth factor receptor precursor; Met proto- oncogene tyrosine kinase; c-met; kinase EC 2.7.10.1; HGF receptor; HGF-SF receptor; Hepatocyte growth factor receptor precursor; Met proto- oncogene tyros |
Category | RTK |
Background | c-Met (MET or MNNG HOS Transforming gene) is a proto-oncogene that encodes a protein known as hepatocyte growth factor receptor (HGFR). MET is a membrane receptor that is essential for embryonic development and wound healing. Hepatocyte growth factor (HGF) is the only known ligand of the MET receptor. MET is normally expressed by cells of epithelial origin, while expression of HGF is restricted to cells of mesenchymal origin. Upon HGF stimulation, MET induces several biological responses that collectively give rise to a program known as invasive growth. Abnormal MET activation in cancer correlates with poor prognosis, where aberrantly active MET triggers tumor growth, formation of new blood vessels (angiogenesis) that supply the tumor with nutrients, and cancer spread to other organs (metastasis). MET is deregulated in many types of human malignancies, including cancers of kidney, liver, stomach, breast, and brain. |
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