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- prospecbio
- ANT-290
- 以色列
- 2025年07月13日
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- 详细信息
- 文献和实验
- 技术资料
- 库存：
大量
- 英文名：
HTLV-1 TAX Mouse antibody
- 保质期：
1年
- 供应商：
上海沪震实业有限公司
- 保存条件：
-20°C
- 规格：
500µg/1mg
CATALOGUE NUMBER
ANT-290
TYPE
Mouse antibody Monoclonal.INTRODUCTION
HTLV-1 is the etiological agent for Adult T-Cell Leukemia which encodes a 40kDa cell-transforming oncoprotein called Tax. HTLV-1 Tax protein sensitizes cells to apoptotic cell death induced by DNA damaging agents. Constitutive Activation of TAK1 by HTLV-1 Tax-dependent Overexpression of TAB2 Induces Activation of JNK-ATF2 but Not IKK-NF-kB.CLONE
YRHTLV-1tax.IMMUNOGEN
r.HTLV TAX protein.IG SUBCLASS
mouse IgG2a.PURIFICATION METHOD
Ion exchange column.FORMULATION
1mg/ml in PBS (after reconstitution).SHIPPING CONDITIONS
Antibody is shipped lyophilized at ambient temperature.STORAGE PROCEDURES
In lyophilized form, for long periods, store at 4°C in a dry environment. After reconstitution, if not intended for use within a month, aliquot and store at -20°C.SOLUBILITY
Reconstitute with H20. Mix gently, wash the sides of the vial and wait 30-60 seconds before use.TITER
By direct ELISA (against recombinant gp24), 1:50,000 dilution will yield 0.5 O.D using alkaline phosphatase conjugated rabbit anti-mouse Ig (Jackson Laboratories).APPLICATIONS
Direct ELISA, Western Blot, Immunoprecipitation.USAGE
Prospec's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.风险提示：丁香通仅作为第三方平台，为商家信息发布提供平台空间。用户咨询产品时请注意保护个人信息及财产安全，合理判断，谨慎选购商品，商家和用户对交易行为负责。对于医疗器械类产品，请先查证核实企业经营资质和医疗器械产品注册证情况。
文献和实验transactivator Tax exerts an essential role in viral transcription as well as in cell transformation. Different experimental methods to study Tax activity on HTLV-LTR promoter and Tax subcellular distribution are described. Emphasis is given to the functional
single-plex assays for HTLV-1 tax-1 , and HTLV-2 tax-2 and pol-2 genes were designed for quantitation of HTLV-1 and HTLV-2 PVLs. The specificity of both tax-2 and pol-2 assays was verified by testing the DNA extracted from C10, a chronically HTLV
Detection of HTLV-1 Gene on Cytologic Smear Slides
in the proteinase K solution on the slides. Last, the template DNA is extracted from the solution and provided to PCR. We use two sets of primers for detection of HTLV-1 genes, and the products of amplification by PCR that correspond to the pX and tax regions
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