NKp44 Antibody

NKp44 Antibody

CATALOGUE NUMBER

ANT-401

SYNONYMS

Natural cytotoxicity triggering receptor 2, Natural killer cell p44-related protein, NK cell-activating receptor, Lymphocyte antigen 95 homolog, NK-p44, NKp44, CD336, NCR2, LY95, dJ149M18.1.

TYPE

Mouse Anti Human Monoclonal.

INTRODUCTION

NCR2 (NKp44) belongs to the natural cytotoxicity receptor (NCR) family which is expressed on activated human NK cells. NKp44 exhibits a single extracellular Ig-like V domain and a transmembrane portion containing the charged residue (Lysine), possibly involved in the association with KARAP/DAP12 molecules. The gene coding for NKp44 maps on human chromosome 6p21.1.

CLONE

P8F12AT.

IMMUNOGEN

Anti-human NKp44 mAb, is derived from hybridization of mouse SP2/0 myeloma cells with spleen cells from BALB/c mice immunized with recombinant human NKp44 amino acids 19-130 purified from E. coli.

IG SUBCLASS

Mouse IgG3 heavy chain and κ light chain.

PURIFICATION METHOD

NKp44 antibody was purified from mouse ascitic fluids by protein-G affinity chromatography.

PHYSICAL APPEARANCE

Sterile filtered colorless solution.

FORMULATION

1mg/ml containing PBS, pH-7.4, & 0.1% Sodium Azide.

STORAGE PROCEDURES

For periods up to 1 month store at 4°C, for longer periods of time, store at -20°C. Prevent freeze thaw cycles.

STABILITY / SHELF LIFE

12 months at -20°C. 1 month at 4°C.

APPLICATIONS

NKp44 antibody has been tested by ELISA and Western blot analysis to assure specificity and reactivity. Since application varies, however, each investigation should be titrated by the reagent to obtain optimal results. Recommended dilution range for Western blot analysis is 1:1,000 ~ 2,000. Recommended starting dilution is 1:1,000.

USAGE

ProSpec's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.