产品概述:MAN2A2 catalyzes the first committed step in the biosynthesis of complex N-glycans. It controls conversion of high mannose to complex N-glycans; the final hydrolytic step in the N-glycan maturation pathway.
靶点/蛋白:This MAN2A2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 767-796 amino acids from the Central region of human MAN2A2.
来源:Rabbit
存储溶液:Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
参考文献:Lesch, K.P., et al. J Neural Transm 115(11):1573-1585(2008)Stelzl, U., et al. Cell 122(6):957-968(2005)Hillman, R.T., et al. Genome Biol. 5 (2), R8 (2004) :Misago, M., et al. Proc. Natl. Acad. Sci. U.S.A. 92(25):11766-11770(1995)
特异性:Human, Mouse
别名:Alpha-mannosidase 2x, Alpha-mannosidase IIx, Man IIx, Mannosidase alpha class 2A member 2, Mannosyl-oligosaccharide 1, 3-1, 6-alpha-mannosidase, MAN2A2, MANA2X
应用:WB~~1:1000IHC-P~~1:10~50FC~~1:10~50
简单描述:Rabbit Polyclonal MAN2A2 Antibody (Center). Validated for use in WB, IHC-P, FC, E.
详情:FunctionCatalyzes the first committed step in the biosynthesis of complex N-glycans. It controls conversion of high mannose to complex N-glycans; the final hydrolytic step in the N-glycan maturation pathway.Cellular_LocationGolgi apparatus membrane; Single-pass type II membrane protein