存储溶液:0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin
参考文献:Synaptic formation in subsets of glutamatergic terminals in the mouse hippocampal formation is affected by a deficiency in the neural cell recognition molecule NB-3. Sakurai K, Toyoshima M, Takeda Y, Shimoda Y, Watanabe K. Neurosci Lett. 2010 Apr 5;473(2):102-6. PMID: 20176085
简单描述:Goat Polyclonal Contactin 6 / NB-3 (mouse aa160-172) Antibody (internal region). Validated for use in E.
详情:FunctionContactins mediate cell surface interactions during nervous system development. Participates in oligodendrocytes generation by acting as a ligand of NOTCH1. Its association with NOTCH1 promotes NOTCH1 activation through the released notch intracellular domain (NICD) and subsequent translocation to the nucleus. Involved in motor coordination (By similarity).Cellular_LocationCell membrane; Lipid-anchor, GPI-anchorTissue_LocationExpressed in nervous system. Highly expressed in cerebellum. Expressed at intermediate level in thalamus, subthalamic nucleus. Weakly expressed in corpus callosum, caudate nucleus and spinal cord