产品概述:Sestrins form a small family of redox enzymes which regulate accumulation of Reactive Oxygen Species. They protect cells and their DNA against oxidative damage and regulate cell growth and viability. These genes are often deregulated in cancers and their inactivation accelerates the growth of model tumors in mice.
靶点/蛋白:This Sestrin-3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 320-347 amino acids from the Central region of human Sestrin-3.
来源:Rabbit
存储溶液:Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
参考文献:Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :Chen, C.C., et al. Dev. Cell 18(4):592-604(2010)Peeters, H., et al. Hum. Genet. 112 (5-6), 573-580 (2003) :
特异性:Human
别名:Sestrin-3, SESN3, SEST3
应用:WB~~1:1000IHC-P~~1:10~50
简单描述:Rabbit Polyclonal Sestrin-3 Antibody (Center Y335). Validated for use in WB, IHC-P, E.