产品概述:Apoptosis regulator. Has anti-apoptotic activity, both for apoptosis triggered via death-receptors and via mitochondrial factors.
靶点/蛋白:Human BFAR
来源:Rabbit
参考文献:Zhang H.,et al.Proc. Natl. Acad. Sci. U.S.A. 97:2597-2602(2000).Ota T.,et al.Nat. Genet. 36:40-45(2004).Martin J.,et al.Nature 432:988-994(2004).Mural R.J.,et al.Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.Roth W.,et al.Cell Death Differ. 10:1178-1187(2003).
特异性:Human, Mouse, Rat
别名:Bifunctional apoptosis regulator, RING finger protein 47, BFAR, BAR, RNF47
应用:IHC-P (5 μg/ml), WB (1-2 μg/ml),
简单描述:Rabbit Polyclonal BAR / BFAR Antibody (C-Terminus). Validated for use in WB, IHC-P, IF, E.
详情:FunctionApoptosis regulator. Has anti-apoptotic activity, both for apoptosis triggered via death-receptors and via mitochondrial factors.Cellular_LocationEndoplasmic reticulum membrane; Multi- pass membrane proteinTissue_LocationExpressed highly in brain, moderately in small intestine, weakly in testes and only faintly in liver and skeletal muscle. Not expressed in heart, kidney, lung and spleen